Institute of Translational Health Sciences

翻译健康科学研究所(IIHS)一直是临床和翻译科学的中心 自2007年以来，华盛顿、怀俄明州、阿拉斯加、蒙大拿州和爱达荷州(WWAMI)。该中心汇集了美国前三大城市 作为合作伙伴的研究机构：华盛顿大学、西雅图儿童基金会和弗雷德·哈钦森 癌症研究中心。该中心的分支是学术、临床、社区和其他研究 整个地区的组织。利用几年来建立的网络和关系，ITS将 继续发展和加强我们的区域合作实验室，一个“没有围墙的中心”，以促进 改善WWAMI和其他地区人民的健康。 对于员工队伍发展，迫切需要明确的职业道路、教育和环境，以便 支持各级临床和翻译研究人员(CTR)的专业成长。ITS将扩大其 以能力为基础的TL1博士前课程有两种方式：在WWAMI大学创建一个队列，并在 在临床培训过程中培养卫生专业学生的翻译研究课程。 研究所将为研究人员建立以能力为基础的培训和职业发展途径。我们 将提供一个学习系统，可以随时按需制作定制的教育内容。 为加强协作和参与，信息与通信技术研究所将制定团队科学，作为CTR的业务标准， 同时培养一种奖励教师晋升中合作的文化。该研究所将整合社区 在翻译研究的所有阶段都有利益相关者的参与。我们将发展农村卫生实验室，将领导权交给 将一个研究项目提供给农村社区，目的是解决一个关键的社区卫生问题。 将特殊人群纳入研究是一项挑战。ITS将促进研究队伍的增长 通过外展、资金支持和嵌入公平的培训，反映所服务的社区 将实践转化为研究团队。我们将纳入计划，以增加整个研究所的劳动力多样性。 ITES将通过将远程技术整合到临床研究中来减少参与研究的障碍 并制定最佳做法，以确保“远程研究”缩小而不是扩大差距。 方法和过程是研究效率和质量的关键。ITS支持的临床试验办公室有 将关键职能整合到一个保护伞下，提供了简化研究流程的机会。 我们将支持跨区域研究网络的研究指标跟踪，使组织能够进行基准 性能以及协作测试和共享流程改进。我们将建立一个支持渠道，以支持 发现研究，以确保更多的健康创新进入临床。 信息学和大数据驱动着未来的创新。ITS将使临床数据科学更容易获得， 为数据探索、机器学习和真实世界证据开发新的方法、工具和教育 分析。我们强调使用电子健康记录在临床上实施循证指南。

The Institute of Translational Health Sciences (ITHS) has served as the clinical and translational science hub for Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI) since 2007. The hub brings together 3 top US research institutions as partners: the University of Washington, Seattle Children’s, and the Fred Hutchinson Cancer Research Center. The spokes of the hub are academic, clinical, community-based, and other research organizations across the region. Leveraging networks and relationships built over several years, ITHS will continue to grow and strengthen our regional Collaboratory, a “center without walls”, to promote research that improves the health of the people across WWAMI and beyond. For Workforce Development, there is a strong need for clear career pathways, education, and environments that support professional growth for clinical and translational researchers (CTR) at all levels. ITHS will expand its competency-based TL1 predoctoral program in 2 ways: creation of a cohort at a WWAMI university and with a translational research curriculum to train health professional students during the course of their clinical training. The Institute will establish competency-based training and career advancement pathways for research staff. We will provide a learning system that can produce tailored educational content on-demand and at any time. To enhance Collaboration and Engagement, ITHS will enact team science as an operational standard in CTR, while cultivating a culture that rewards collaboration in faculty promotion. The Institute will integrate community stakeholders at all stages of translational research. We will develop a Rural Health Lab handing the leadership of a research project to a rural community with the aim to tackle a critical community health issue. Integrating Special Populations in research is a challenge. ITHS will promote the growth of a research workforce reflective of the communities served, through outreach, funding support, and training that embeds equity practices into research teams. We will incorporate programs to increase workforce diversity across the Institute. ITHS will reduce barriers to research participation through integration of remote technologies into clinical studies and develop best practices to ensure that “teleresearch” reduces rather than amplifies disparities. Methods and Processes are key to efficiency and quality in research. ITHS supported clinical trials offices have consolidated key functions under a single umbrella, providing opportunities to streamline research processes. We will support study metric tracking across a regional research network, enabling organizations to benchmark performance and collaboratively test and share process improvements. We will develop a pipeline of support for discovery research to ensure more health innovations reach the clinic. Informatics and “big data” drive future innovation. ITHS will make clinical data science more accessible, developing new methods, tools, and education for data exploration, machine learning, and real-world evidence analysis. We emphasize use of the electronic health record to implement evidence-based guidelines in the clinic.