Institute of Translational Health Sciences

转化健康科学研究所

• 批准号: 10595094
• 负责人: Mary L. Disis
• 金额: $ 1051.44万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10595094
• 关键词: Alaska; Benchmarking; Big Data; Career Choice; Career Mobility; Child; Clinic; Clinical; Clinical Data; Clinical Research; Clinical Sciences; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Communities; Community Health; Competence; Data Science; Disparity; Education; Educational Curriculum; Electronic Health Record; Ensure; Environment; Equity; Faculty; Fostering; Fred Hutchinson Cancer Research Center; Funding; Future; Goals; Growth; Guidelines; Health; Healthcare; Idaho; Individual; Informatics; Infrastructure; Institution; Investments; Laboratories; Leadership; Learning; Location; Longevity; Machine Learning; Methods; Minority Groups; Montana; Pathway interactions; Patients; Performance; Persons; Phase; Policies; Predictive Analytics; Process; Publications; Relationship-Building; Research; Research Personnel; Research Project Grants; Resources; Rewards; Role; Rural Community; Rural Health; Rural Population; Science; Services; Special Population; System; TNFSF15 gene; Technology; Testing; Time; Training; Training and Education; Translational Research; Universities; Vision; Washington; Workforce Development; Wyoming; clinical training; cohort; collaboratory; community engagement; data exploration; data sharing; diversity and equity; doctoral student; early-career faculty; evidence based guidelines; health training; improved; informatics tool; innovation; novel; outreach; pre-doctoral; process improvement; professional students; programs; research to practice; skills; success; tool; translational health science; translational scientist

The Institute of Translational Health Sciences (ITHS) has served as the clinical and translational science hub for Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI) since 2007. The hub brings together 3 top US research institutions as partners: the University of Washington, Seattle Children’s, and the Fred Hutchinson Cancer Research Center. The spokes of the hub are academic, clinical, community-based, and other research organizations across the region. Leveraging networks and relationships built over several years, ITHS will continue to grow and strengthen our regional Collaboratory, a “center without walls”, to promote research that improves the health of the people across WWAMI and beyond. For Workforce Development, there is a strong need for clear career pathways, education, and environments that support professional growth for clinical and translational researchers (CTR) at all levels. ITHS will expand its competency-based TL1 predoctoral program in 2 ways: creation of a cohort at a WWAMI university and with a translational research curriculum to train health professional students during the course of their clinical training. The Institute will establish competency-based training and career advancement pathways for research staff. We will provide a learning system that can produce tailored educational content on-demand and at any time. To enhance Collaboration and Engagement, ITHS will enact team science as an operational standard in CTR, while cultivating a culture that rewards collaboration in faculty promotion. The Institute will integrate community stakeholders at all stages of translational research. We will develop a Rural Health Lab handing the leadership of a research project to a rural community with the aim to tackle a critical community health issue. Integrating Special Populations in research is a challenge. ITHS will promote the growth of a research workforce reflective of the communities served, through outreach, funding support, and training that embeds equity practices into research teams. We will incorporate programs to increase workforce diversity across the Institute. ITHS will reduce barriers to research participation through integration of remote technologies into clinical studies and develop best practices to ensure that “teleresearch” reduces rather than amplifies disparities. Methods and Processes are key to efficiency and quality in research. ITHS supported clinical trials offices have consolidated key functions under a single umbrella, providing opportunities to streamline research processes. We will support study metric tracking across a regional research network, enabling organizations to benchmark performance and collaboratively test and share process improvements. We will develop a pipeline of support for discovery research to ensure more health innovations reach the clinic. Informatics and “big data” drive future innovation. ITHS will make clinical data science more accessible, developing new methods, tools, and education for data exploration, machine learning, and real-world evidence analysis. We emphasize use of the electronic health record to implement evidence-based guidelines in the clinic.

转化健康科学研究所（ITHS）已成为 自2007年以来 作为合作伙伴的研究机构：华盛顿大学，西雅图儿童和弗雷德·哈钦森 癌症研究中心。枢纽的辐条是学术，临床，基于社区和其他研究 整个地区的组织。利用网络和建立的网络和关系，ITH将 继续增长和加强我们的区域合作组织，即“无墙的中心”，以促进研究 改善第二次世界大战及以后的人民的健康。 对于劳动力发展，非常需要清晰的职业道路，教育和环境 支持各级临床和翻译研究人员（CTR）的专业增长。 ITH将扩大其 以两种方式：基于能力的TL1前专业计划：在WWAMI大学创建队列 翻译研究课程在临床培训期间培训卫生专业学生。 该研究所将为研究人员建立基于能力的培训和职业发展途径。我们 将提供一个学习系统，该系统可以随时随地产生量身定制的教育内容。 为了增强协作和参与，ITHS将在CTR中颁布团队科学作为运营标准， 在培养一种奖励教师促进的文化的同时。该研究所将整合社区 转化研究的各个阶段的利益相关者。我们将开发一个农村健康实验室，递给领导 向粗糙社区进行的研究项目，目的是解决关键的社区健康问题。 将特殊人群融入研究是一个挑战。 ITHS将促进研究人员的成长 通过外展，资金支持和嵌入股权的培训来反映所服务的社区 练习研究团队。我们将合并计划以增加研究所的劳动力多样性。 ITH将通过将远程技术整合到临床研究中来减少研究参与的障碍 并开发最佳实践，以确保“ Telesearch”减少而不是放大器分布。 方法和过程是研究效率和质量的关键。 ITH支持的临床试验办公室有 在单个保护伞下合并关键功能，提供了简化研究过程的机会。 我们将支持跨区域研究网络的研究指标跟踪，使组织能够基准测试 性能和协作测试和共享过程改进。我们将建立支持的管道 发现研究以确保更多的健康创新到达诊所。 信息学和“大数据”推动了未来的创新。 ITH将使临床数据科学更容易访问， 为数据探索，机器学习和现实证据开发新的方法，工具和教育 分析。我们强调使用电子健康记录来在诊所实施基于证据的指南。