Institute of Translational Health Sciences
转化健康科学研究所
基本信息
- 批准号:10524284
- 负责人:
- 金额:$ 1048.91万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-06-01 至 2027-02-28
- 项目状态:未结题
- 来源:
- 关键词:AbbreviationsAdvisory CommitteesAlaskaAlaska NativeAmerican IndiansAppointmentBenchmarkingBig DataBiometryBody mass indexCareer ChoiceCareer MobilityChildClinicClinicalClinical DataClinical ResearchClinical SciencesClinical TrialsClinical and Translational Science AwardsCollaborationsCommunitiesCommunity HealthCompetenceData ScienceDevicesDissemination and ImplementationEducationEducational CurriculumElectronic Health RecordEnsureEnvironmentEvaluation ResearchFacultyFosteringFred Hutchinson Cancer Research CenterFundingFutureGoalsGovernmentGrowthGuidelinesHandHealthHealth ProfessionalHealthcareIdahoIndividualInformaticsInfrastructureInstitutesInstitutionInstitutional Review BoardsInvestmentsKnowledgeLaboratoriesLeadershipLearningLocationLongevityMachine LearningMethodsMinority GroupsMontanaNatural Language ProcessingParticipantPathway interactionsPatientsPerformancePersonsPharmaceutical PreparationsPhasePoliciesPredictive AnalyticsProcessPublicationsResearchResearch DesignResearch PersonnelResearch Project GrantsResourcesRewardsRoleRural CommunityRural HealthRural PopulationScienceServicesSpecial PopulationStudentsSystemTNFSF15 geneTechnologyTestingTimeTrainingTraining and EducationTranslational ResearchUnderrepresented MinorityUniversitiesVisionWashingtonWorkforce DevelopmentWyomingbasebiomedical informaticscancer carecohortcollaboratorycommercializationcommunity engagementdata explorationdata resourcedata sharingdata warehousediversity and equityearly-career facultyepidemiology studyequity diversity and inclusionevidence based guidelineshealth trainingimprovedinformatics toolinnovationnoveloutreachpre-doctoralprogramsresearch to practicescience educationskillssuccesstooltranslational health sciencetranslational scientist
项目摘要
Contact PD/PI: Disis, Mary L.
The Institute of Translational Health Sciences (ITHS) has served as the clinical and translational science hub for
Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI) since 2007. The hub brings together 3 top US
research institutions as partners: the University of Washington, Seattle Children’s, and the Fred Hutchinson
Cancer Research Center. The spokes of the hub are academic, clinical, community-based, and other research
organizations across the region. Leveraging networks and relationships built over several years, ITHS will
continue to grow and strengthen our regional Collaboratory, a “center without walls”, to promote research that
improves the health of the people across WWAMI and beyond.
For Workforce Development, there is a strong need for clear career pathways, education, and environments that
support professional growth for clinical and translational researchers (CTR) at all levels. ITHS will expand its
competency-based TL1 predoctoral program in 2 ways: creation of a cohort at a WWAMI university and with a
translational research curriculum to train health professional students during the course of their clinical training.
The Institute will establish competency-based training and career advancement pathways for research staff. We
will provide a learning system that can produce tailored educational content on-demand and at any time.
To enhance Collaboration and Engagement, ITHS will enact team science as an operational standard in CTR,
while cultivating a culture that rewards collaboration in faculty promotion. The Institute will integrate community
stakeholders at all stages of translational research. We will develop a Rural Health Lab handing the leadership
of a research project to a rural community with the aim to tackle a critical community health issue.
Integrating Special Populations in research is a challenge. ITHS will promote the growth of a research workforce
reflective of the communities served, through outreach, funding support, and training that embeds equity
practices into research teams. We will incorporate programs to increase workforce diversity across the Institute.
ITHS will reduce barriers to research participation through integration of remote technologies into clinical studies
and develop best practices to ensure that “teleresearch” reduces rather than amplifies disparities.
Methods and Processes are key to efficiency and quality in research. ITHS supported clinical trials offices have
consolidated key functions under a single umbrella, providing opportunities to streamline research processes.
We will support study metric tracking across a regional research network, enabling organizations to benchmark
performance and collaboratively test and share process improvements. We will develop a pipeline of support for
discovery research to ensure more health innovations reach the clinic.
Informatics and “big data” drive future innovation. ITHS will make clinical data science more accessible,
developing new methods, tools, and education for data exploration, machine learning, and real-world evidence
analysis. We emphasize use of the electronic health record to implement evidence-based guidelines in the clinic.
Project Summary/Abstract Page 304
Contact PD/PI: Disis, Mary L.
The Institute of Translational Health Sciences (ITHS) seeks to improve the quality and efficiency of clinical and
translational research across Washington, Wyoming, Alaska, Montana, and Idaho and beyond. The Institute will
achieve this goal through education and training, team building, community engagement, continuous process
improvement, and advanced informatics.
联系PD/PI: Disis, Mary L。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Mary L. Disis其他文献
Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop
- DOI:
10.1186/s40425-019-0640-y - 发表时间:
2019-07-04 - 期刊:
- 影响因子:10.600
- 作者:
Davide Bedognetti;Michele Ceccarelli;Lorenzo Galluzzi;Rongze Lu;Karolina Palucka;Josue Samayoa;Stefani Spranger;Sarah Warren;Kwok-Kin Wong;Elad Ziv;Diego Chowell;Lisa M. Coussens;Daniel D. De Carvalho;David G. DeNardo;Jérôme Galon;Howard L. Kaufman;Tomas Kirchhoff;Michael T. Lotze;Jason J. Luke;Andy J. Minn;Katerina Politi;Leonard D. Shultz;Richard Simon;Vésteinn Thórsson;Joanne B. Weidhaas;Maria Libera Ascierto;Paolo Antonio Ascierto;James M. Barnes;Valentin Barsan;Praveen K. Bommareddy;Adrian Bot;Sarah E. Church;Gennaro Ciliberto;Andrea De Maria;Dobrin Draganov;Winson S. Ho;Heather M. McGee;Anne Monette;Joseph F. Murphy;Paola Nisticò;Wungki Park;Maulik Patel;Michael Quigley;Laszlo Radvanyi;Harry Raftopoulos;Nils-Petter Rudqvist;Alexandra Snyder;Randy F. Sweis;Sara Valpione;Roberta Zappasodi;Lisa H. Butterfield;Mary L. Disis;Bernard A. Fox;Alessandra Cesano;Francesco M. Marincola - 通讯作者:
Francesco M. Marincola
Immunologic biomarkers as correlates of clinical response to cancer immunotherapy
- DOI:
10.1007/s00262-010-0960-8 - 发表时间:
2011-01-08 - 期刊:
- 影响因子:5.100
- 作者:
Mary L. Disis - 通讯作者:
Mary L. Disis
Tumor stromal barriers to the success of adoptive T cell therapy
- DOI:
10.1007/s00262-007-0356-6 - 发表时间:
2007-07-24 - 期刊:
- 影响因子:5.100
- 作者:
Vy Phan;Mary L. Disis - 通讯作者:
Mary L. Disis
Vaccines for breast cancer prevention: Are we there yet?
预防乳腺癌的疫苗:我们还在吗?
- DOI:
10.1016/j.mam.2024.101292 - 发表时间:
2024-08-01 - 期刊:
- 影响因子:10.300
- 作者:
Shaveta Vinayak;Denise L. Cecil;Mary L. Disis - 通讯作者:
Mary L. Disis
SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art
- DOI:
10.1186/s40425-018-0453-4 - 发表时间:
2018-12-01 - 期刊:
- 影响因子:10.600
- 作者:
Lisa H. Butterfield;Mary L. Disis;Bernard A. Fox;David R. Kaufman;Samir N. Khleif;Ena Wang - 通讯作者:
Ena Wang
Mary L. Disis的其他文献
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{{ truncateString('Mary L. Disis', 18)}}的其他基金
Developing Community-Responsive mHealth and AI/ML: Understanding Perspectives of Hispanic Community Members in Washington State
开发社区响应型移动医疗和人工智能/机器学习:了解华盛顿州西班牙裔社区成员的观点
- 批准号:
10598360 - 财政年份:2022
- 资助金额:
$ 1048.91万 - 项目类别:
CTSA INFRASTRUCTURE FOR PEDIATRIC CLINICAL TRIALS
用于儿科临床试验的 CTSA 基础设施
- 批准号:
8365201 - 财政年份:2011
- 资助金额:
$ 1048.91万 - 项目类别:
Vaccinating against IGFBP-2 to prevent ovarian cancer relapse
接种 IGFBP-2 疫苗可预防卵巢癌复发
- 批准号:
8322539 - 财政年份:2011
- 资助金额:
$ 1048.91万 - 项目类别:
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