Multibeam Healing for Laser Micromachining in Manufacturing

制造业激光微加工的多光束修复

• 批准号: 7670766
• 负责人: BIPIN SINGH
• 金额: $ 77.01万
• 依托单位: RADIATION MONITORING DEVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7670766
• 关键词: Ablation; Address; Animals; Area; Behavior; Berlin; Beryllium; Biological Process; Biomedical Engineering; California; Caregivers; Ceramics; Characteristics; Cherry - dietary; Clinic; Collaborations; Communities; Complement; Consultations; Defect; Development; Diagnosis; Diagnostic Imaging; Diagnostic radiologic examination; Diamond; Digital Libraries; Discipline of Nuclear Medicine; Drops; Economics; Elements; Eligibility Determination; Engineering; Ensure; Environment; Equipment; Evaluation; Film; Foundations; Fracture; France; Funding; Future; Future Generations; Gadolinium; Generations; Goals; Government; Grant; Growth; Healed; Health; Healthcare; Height; Human; Image; Imaging technology; Implant; Individual; Inferior; Institution; Joints; Knowledge; LSO crystal; Lasers; Lead; Letters; Lutetium; Magnetic Resonance Imaging; Manuals; Manufacturer Name; Marketing; Measures; Mechanics; Medical; Medical Imaging; Medical Technology; Methods; Modality; Modeling; Morphology; Nuclear; Optics; Orthopedics; Outcome; Paper; Patients; Pattern; Pennsylvania; Performance; Persons; Phase; Philadelphia; Physics; Positron-Emission Tomography; Probability; Procedures; Process; Production; Property; Protocols documentation; Publishing; Radiology Specialty; Reliability of Results; Reporting; Research; Research Personnel; Resolution; Rewards; Saints; Science; Shapes; Side; Solutions; Specimen; Stress; Structure; Surface; System; Systems Development; Techniques; Technology; Text; Time; Universities; Width; Work; Writing; X-Ray Computed Tomography; Yttrium; authority; base; commercial application; commercialization; cost; cost effective; density; design; detector; energy density; experience; gadolinium oxide; gadolinium oxyorthosilicate; healing; improved; innovation; interest; manufacturing process; meetings; microsystems; millimeter; novel; prevent; professor; programs; repository; research study; simulation; single photon emission computed tomography; technology development; thermal stress; yttria

DESCRIPTION (provided by applicant): There is considerable interest in new and innovative manufacturing methods for medical imaging technologies to enhance performance while reducing cost. The precision and low-force signature of lasers makes them very attractive alternatives to traditional machining methods for brittle materials, particularly scintillators such as lutetium oxyorthosilicate (LSO), gadolinium oxyorthosilciate (GSO), lutetium-yttrium oxyorthosilicate (LYSO), etc. used in high-resolution diagnostic imaging and nuclear medicine. However, material damage, especially micro-scale cracking, during laser machining is a frequently encountered problem that results in added costs, needless scrap, and reduced performance/reliability. These issues have prevented the tremendous commercial potential of laser machining from being fully utilized to manufacture large and finely pixelated scintillator arrays. The goal of the Phase I research was to demonstrate the feasibility of defect free laser machining of brittle scintillators using a novel multibeam approach. We are pleased to report that the Phase I research has not only clearly demonstrated the feasibility of our approach but has also led to a major discovery that has the potential to dramatically reduce the cost and duration of pixelation. Thus our Phase I effort has laid a firm foundation for achieving our ultimate goal of defect-free manufacturing of scintillator arrays using laser machining. With these exceptional results, the technique of laser pixelation and multibeam healing is now poised for exploitation in rapid and cost effective systems for micro-machining arrays of various sizes, shapes, and orientations in scintillators of critical importance to medical and non-medical applications. The proposed research is designed to address manufacturing issues through detailed simulation studies of the material's behavior during laser ablation, and by implementing a new laser beam delivery system based on experimental findings that confirm the simulation results. Developing such a system and a body of knowledge in scintillator micro-machining will allow fabricating large arrays of various scintillators at significantly reduced manufacturing cost, while greatly improving detector performance with reduced pixel sizes and inter-pixel gaps. Therefore, the proposed research has great commercial relevance, especially for modalities as PET where higher resolution and lower cost is critically important.

描述（由申请人提供）：对医学成像技术的新的和创新的制造方法引起了极大的兴趣，以提高性能，同时降低成本。激光器的精确和低强度特征使它们非常有吸引力的材料传统加工方法，尤其是闪烁的闪烁剂，例如氧基氧硅酸盐（LSO），高氧硅氧硅氧甲硅氧硅（GSO）（GSO），露铁 - 含氧核酸盐（lutetium-Yttrium-Yttrium-Yttrium oxyartium oxyartium），氧基硅烷酸酯（Lyso）等。但是，在激光加工期间，材料损坏，尤其是微型开裂，是一个经常遇到的问题，会导致成本增加，不必要的废料和降低性能/可靠性。这些问题阻止了激光加工的巨大商业潜力，无法完全利用用于制造大型且精细的闪烁体阵列。第一阶段研究的目的是证明使用新型的多束方法对脆性闪烁体进行无缺陷激光加工的可行性。我们很高兴地报告，I阶段研究不仅清楚地证明了我们方法的可行性，而且还导致了一个重大发现，该发现有可能大大降低像素化的成本和持续时间。因此，我们的第一阶段努力为实现了使用激光加工的闪烁阵列制造的最终目标奠定了坚定的基础。通过这些出色的结果，现在有助于在快速且具有成本效益的系统中剥削激光像素化和多束愈合的技术，用于在对医疗和非医学应用至关重要的闪烁体中的各种尺寸，形状和方向的微观阵列。拟议的研究旨在通过对激光消融过程中材料行为的详细模拟研究来解决制造问题，并通过基于确认模拟结果的实验​​发现实施新的激光束输送系统。开发这种系统和闪烁体微型处理中的知识体系，将允许以大大降低的制造成本制造大量的各种闪光灯，同时，通过降低像素尺寸和像素间差异，可以大大提高探测器性能。因此，拟议的研究具有很大的商业意义，尤其是对于较高的分辨率和较低成本至关重要的宠物而言，至关重要。