COMMUNITY CHILD HEALTH NETWORK- LOS ANGELES

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 本研究的主要目的是研究社区，家庭和个人水平的影响如何与生物影响相互作用，并导致怀孕结果的健康差异。 该研究将社会，行为和生物医学方法融合到一个连贯的社区相关研究中。 儿童保健网的总体目标是对产妇保健和儿童发展方面的差异原因有新的认识。这项多中心研究的总体目标是检查与“母体非稳态负荷”相关的因素。母体非稳态负荷是指心理社会和环境压力对身体的“磨损”。 该研究的假设是，这种“磨损”可能在不良的妊娠和儿童健康结果中发挥作用。具体目标是： (1)确定什么样的压力源对母婴结局的影响最大， (2)探索这种“磨损”与随后的出生/儿童健康结果的关系。 我们将在所有入组受试者及其配偶/伴侣入组研究后随访2年。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The principal goal of this study is to examine how community, family, and individual level influences interact with biological influences and result in health disparities in pregnancy outcomes. The research blends social, behavioral, and biomedical approaches into a coherent community-linked study. The overall goal of the CCHN is to gain new insights into the reasons for the disparities in maternal health and child development. The overall goal of this multi-site study is to examine the factors associated with "maternal allostatic load." Maternal allostatic load is a term for the "wear and tear" on the body from psychosocial and environmental stressors. The hypothesis of the study is that this kind of "wear and tear" may play a role in poor pregnancy and child health outcomes. The specific aims are to: (1) determine what kinds of stressors have the most affect on maternal-child outcomes, (2) explore the relationship of this "wear and tear" on subsequent birth/child health outcomes. We will follow all enrolled participants and their spouses/partners for two years after they enroll in the study.