CLINICAL TRIAL: TRIAL TO EVALUATE THE EFFECTIVENESS AND SAFETY OF DIFF DOSES OF
临床试验:评估不同剂量的有效性和安全性的试验
基本信息
- 批准号:8174509
- 负责人:
- 金额:$ 6.91万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-12-01 至 2010-11-30
- 项目状态:已结题
- 来源:
- 关键词:AxillaBloodClinical TrialsComputer Retrieval of Information on Scientific Projects DatabaseCutaneousDoseDrug FormulationsDrug KineticsEffectivenessFundingGelGrantHormonesHuman bodyInjection of therapeutic agentInstitutionLotionMeasuresOralOral cavityPharmaceutical PreparationsResearchResearch PersonnelResourcesSafetySkinSolutionsSourceTestosteroneTimeUnited States National Institutes of Healthmalemenskin irritationtestosterone replacement therapytreatment duration
项目摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
The purpose of this study is to determine how a new formulation of male hormone Testosterone MD-Lotion¿ (cutaneous solution) is metabolized by human body and if it is safe and well tolerated. This will be done by giving different doses of Testosterone MD-Lotion¿ applied to the skin (cutaneous solution) to hypogonadal men (men deficient in male hormone testosterone) and measuring how much of the medication remains in the blood at set time points (pharmacokinetics, PK). Testosterone MD-Lotion¿ (cutaneous solution) comes in a form of a lotion to be applied to the skin of axillae (armpits). The study will take up to 24 weeks to complete and all subjects will receive the active study medication for 120 days of the Treatment Period of the study.
Testosterone replacement therapies currently available include oral formulations (taken by mouth), injections, gel and gel patches (to be applied to skin). Testosterone MD-Lotion¿ may provide another way to apply testosterone to the skin in addition to the available gel formulations of testosterone. The testosterone lotion is applied to the axillae, has minimal skin irritation, and may decrease chances of transferring the medication to others.
这个子项目是众多研究子项目之一
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
CHRISTINA C. WANG其他文献
CHRISTINA C. WANG的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('CHRISTINA C. WANG', 18)}}的其他基金
Community Outreach and Education Core (Core B)
社区外展和教育核心(核心 B)
- 批准号:
10018081 - 财政年份:2019
- 资助金额:
$ 6.91万 - 项目类别:
Community Outreach and Education Core (Core B)
社区外展和教育核心(核心 B)
- 批准号:
10615594 - 财政年份:2019
- 资助金额:
$ 6.91万 - 项目类别:
Community Outreach and Education Core (Core B)
社区外展和教育核心(核心 B)
- 批准号:
10260437 - 财政年份:2019
- 资助金额:
$ 6.91万 - 项目类别:
HYPOPITUITARISM IN RETIRED PROFESSIONAL FOOTBALL PLAYERS
退役职业足球运动员的垂体功能低下
- 批准号:
8174513 - 财政年份:2009
- 资助金额:
$ 6.91万 - 项目类别:
CLINICAL TRIAL: A MULTIPLE DOSE, PHARMACOKINETIC STUDY
临床试验:多剂量药代动力学研究
- 批准号:
8174500 - 财政年份:2009
- 资助金额:
$ 6.91万 - 项目类别:
A MULTICENTER, RANDOMIZED COMPARATOR TRIAL OF THE SAFETY AND SPERM AND GONADOTRO
安全性与精子和促性腺激素的多中心、随机比较试验
- 批准号:
8174515 - 财政年份:2009
- 资助金额:
$ 6.91万 - 项目类别:
DEVELOPMENT AND VALIDATION OF STEROID AND OTHER ASSAYS BY LIQUID CHROMATOGRAPHY
类固醇和其他液相色谱分析方法的开发和验证
- 批准号:
8174528 - 财政年份:2009
- 资助金额:
$ 6.91万 - 项目类别:
相似海外基金
Blood & Marrow Clinical Trials Network- Hutchinson Center as Core Clinical Site
血
- 批准号:
10430215 - 财政年份:2022
- 资助金额:
$ 6.91万 - 项目类别:
Blood & Marrow Clinical Trials Network- Hutchinson Center as Core Clinical Site
血
- 批准号:
10673065 - 财政年份:2022
- 资助金额:
$ 6.91万 - 项目类别:
Blood & Marrow Clinical Trials Network- Hutchinson Center as Core Clinical Site
血
- 批准号:
10652543 - 财政年份:2022
- 资助金额:
$ 6.91万 - 项目类别:
Core Clinical Centers for the Blood and Marrow Transplant Clinical Trials Network
血液和骨髓移植临床试验网络核心临床中心
- 批准号:
10434795 - 财政年份:2017
- 资助金额:
$ 6.91万 - 项目类别:
Blood and Marrow Transplant Clinical Trials Network Data Coordinating Center
血液和骨髓移植临床试验网络数据协调中心
- 批准号:
9981802 - 财政年份:2017
- 资助金额:
$ 6.91万 - 项目类别:
Core Clinical Centers for the Blood and Marrow Transplant Clinical Trials Network
血液和骨髓移植临床试验网络核心临床中心
- 批准号:
10187640 - 财政年份:2017
- 资助金额:
$ 6.91万 - 项目类别:
Core Clinical Centers for the Blood and Marrow Transplant Clinical Trials Network
血液和骨髓移植临床试验网络核心临床中心
- 批准号:
10657476 - 财政年份:2017
- 资助金额:
$ 6.91万 - 项目类别:
Blood and Marrow Transplant Clinical Trials Network Data Coordinating Center
血液和骨髓移植临床试验网络数据协调中心
- 批准号:
10684204 - 财政年份:2017
- 资助金额:
$ 6.91万 - 项目类别:
Blood and Marrow Transplant Clinical Trials Network Data Coordinating Center
血液和骨髓移植临床试验网络数据协调中心
- 批准号:
10249236 - 财政年份:2017
- 资助金额:
$ 6.91万 - 项目类别:
Core Clinical Centers for the Blood and Marrow Transplant Clinical Trials Network
血液和骨髓移植临床试验网络核心临床中心
- 批准号:
9384841 - 财政年份:2017
- 资助金额:
$ 6.91万 - 项目类别: