Community Outreach and Education Core (Core B)

社区外展和教育核心（核心 B）

• 批准号: 10615594
• 负责人: CHRISTINA C. WANG
• 金额: $ 11.62万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-13 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10615594
• 关键词: Academia; Affect; African; African American; Awareness; Biomedical Research; Body Weight decreased; California; Cardiovascular Diseases; Child; Clinical Sciences; Collaborations; Communication; Communities; Community Health; Community Health Education; Community Outreach; Conflict of Interest; Daughter; Disease; Education; Education and Outreach; Educational workshop; Endowment; Environment; Epigenetic Process; Equity; Family; Future; Gene Expression; Gene Expression Regulation; Genomics; Glucose Intolerance; Goals; Hawaii; Health; Health Promotion and Education; High School Student; Hispanic; Hypertension; Infrastructure; Institution; Insulin Resistance; Kidney Diseases; Knowledge; Lead; Life Style; Link; Los Angeles; Medical; Medical center; Metabolic Diseases; Metabolic syndrome; Methods; Modification; Names; National Center for Advancing Translational Sciences; Native Hawaiian; Native Hawaiian or Other Pacific Islander; Needs Assessment; Nevada; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Pacific Islander; Parents; Phenotype; Procedures; Race; Reproductive Health; Research; Research Institute; Research Personnel; Role; Stroke; Structure; Surveys; Texas; Translational Research; Trust; Unhealthy Diet; Universities; Youth; cardiovascular risk factor; college; community engagement; conflict resolution; design; disease phenotype; disease transmission; egg; epigenetic regulation; epigenome; epigenomics; evidence base; experience; health disparity; high school; high school program; improved; intergenerational; male; next generation; novel; obesity management; offspring; operation; physical inactivity; programs; reproductive; sperm cell; summer program; symposium; transmission process; university student; web site; working group; young adult; young man; young woman

The Community Outreach and Education Core of the Center for Male Reproductive Epigenomics will be located and operated though Los Angeles Biomedical Research Institute (LA Biomed) at Harbor-UCLA Medical Center located in South West Los Angeles. This Core will develop outreach and education programs designed to disseminate information on the effects of life styles on the epigenetic regulation of sperm gene expression that may be transmitted to the next generation. Our theme is to promote “Healthy life style, Healthy sperm epigenome, Healthy babies”. Building on our prior collaboration and community-academic partnership, we plan to achieve our goals by engaging youths, high school and college students, and younger adults from our communities to disseminate information on reproductive epigenomics and their effects on the next generation. We have four aims: Aim 1. Promote and sustain bidirectional knowledge sharing between the community and academic institutions by providing opportunities for networking and developing a community specific dissemination plan for evidence based information on how obesity and inactivity change the sperm epigenome transmitting unhealthy phenotype and epigenotype to the next generation. Aim 2. Create educational programs, workshops and conferences to engage younger adults, college and high school students (future parents) to disseminate information on “healthy life styles, healthy reproductive epigenome; healthy babies”. With our partners we will conduct community-partnered research conferences and workshops for younger adults, and summer program for high school and college students to provide knowledge transfer on the impact of environment on epigenetics? how improvement in the environment may reverse maladaptive epigenetic changes? and how epigenetics are linked to intergenerational transmission of disease phenotype? Aim 3. Develop a community focused website for the Center for Male Reproductive Genomics. Working with our community partners, academic partners at the University of Nevada Reno and the University of Texas San Antonio, we will develop a culturally and racially sensitive website to provide information on the role of epigenomics in reproductive health in general and impact of sperm epigenomics on next generation’s health. Aim 4. Establish the governance and operation structure of the Community Core Advisory Council that strengthens existing partnerships and builds new bridges between community and academia for education and research.

男性生殖表观基因组学中心的社区外展和教育核心将找到 并在Harbour-Ucla医疗中心的洛杉矶生物医学研究所（LA BIOMED）经营 位于西南洛杉矶。该核心将制定旨在的外展和教育计划 传播有关生命方式对精子基因表达表观遗传调节的影响的信息 可能会传输到下一代。我们的主题是促进“健康的生活方式，健康的精子 表观基因组，健康的婴儿”。基于我们先前的合作和社区学术伙伴关系，我们计划 通过吸引年轻人，高中和大学生以及我们的年轻人来实现我们的目标 社区传播有关生殖表观基因组学及其对下一代的影响的信息。 我们有四个目标：目标1。促进和维持社区之间的双向知识共享 学术机构通过为网络和开发社区特定的机会提供机会 有关肥胖和不活跃如何改变精子基因组的基于证据的信息的传播计划 将不健康的表型和表观型传输到下一代。目标2。创建教育计划， 讲习班和会议，让年轻人，大学和高中生（未来的父母）与 传播有关“健康生活方式，健康生殖表观基因组；健康婴儿”的信息。与我们的 合作伙伴我们将为年轻人举办社区合作的研究会议和研讨会，以及 高中和大学生的夏季计划，以提供有关影响的知识转移 表观遗传学的环境？环境中的改善如何逆转适应不良的表观遗传学 变化？以及表观遗传学如何与疾病表型的代际传播有关？目标3。 为男性生殖基因组学中心开发一个以社区为本的网站。与我们一起工作 内华达大学里诺大学和德克萨斯大学SAN的社区合作伙伴，学术合作伙伴 安东尼奥（Antonio），我们将在文化和粗略敏感的网站上开发一个有关角色的信息 生殖健康的表观基因组学总体上以及精子表观基因组学对下一代健康的影响。 目标4。建立社区核心咨询委员会的治理和运营结构 优势现有的伙伴关系，并在社区和学术界之间建立新的桥梁，以进行教育和 研究。