NMR STUDY OF SMALL HEAT SHOCK PROTEIN (HSP12) FROM CESG

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 CESGHSP 12中小分子热休克未折叠蛋白（HSP 12）的NMR研究CESGHSP 12是一种小分子热休克蛋白，保护膜不受脱水，在常规NMR缓冲液中未折叠。初步研究表明，这种蛋白质在洗涤剂（SDS）的存在下折叠。我们计划在SDS存在的情况下确定结构。此外，我们使用HIFI快速数据方法来分配蛋白质。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. NMR study of small heat shock unfolded protein (HSP12) from CESGHSP12 is a small heat shock protein, which protects the membrane from dehydration and is unfolded in regular NMR buffer. Priliminary studies indicate this protein folds in presence of detergents (SDS). we are planning to determine the structure in presence of SDS. In addition we are using HIFI fast data method to assign the protein.