RSR1 AND THE ESTABLISHMENT OF CELL POLARITY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 细胞极化沿着单个轴发生，该轴通常响应于空间线索而确定。在芽殖酵母中，Rsr 1 GTdR及其调节因子在响应细胞类型特异性线索的适当皮层位置指导细胞极性的建立。我们有兴趣通过FRET探索Rsr 1的相互作用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cell polarization occurs along a single axis that is generally determined in response to spatial cues. In budding yeast, the Rsr1 GTPase and its regulators direct the establishment of cell polarity at the proper cortical location in response to cell-type-specific cues. We are interested in exploring the interactions of Rsr1 by FRET.