2011 US-HUPO Conference -- Proteomics: New Developments and Grand Challenges

2011年US-HUPO会议——蛋白质组学：新进展与重大挑战

• 批准号: 8128049
• 负责人: David C. Muddiman
• 金额: $ 2.5万
• 依托单位: NORTH CAROLINA STATE UNIVERSITY RALEIGH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-18 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8128049
• 关键词: Address; Affect; Animal Model; Biological; Biological Assay; Biological Markers; Biosensor; Businesses; Cardiovascular Diseases; Cells; Clinic; Clinical; Coffee; Collaborations; Communicable Diseases; Complement; Country; Development; Diabetes Mellitus; Diagnostic; Disabled Persons; Discipline; Disease; Early Diagnosis; Educational Activities; Educational workshop; Experimental Designs; Faculty; Feedback; Fostering; Foundations; Funding; Funding Applicant; Future; Goals; Growth; Health; Historically Black Colleges and Universities; Human; Institution; Intervention; Laboratories; Learning; Liquid substance; Mails; Malignant Neoplasms; Maryland; Mass Spectrum Analysis; Methods; Minority; Minority Groups; Minority-Serving Institution; Mission; North Carolina; Obesity; Oral; Participant; Persons; Postdoctoral Fellow; Protein Microchips; Proteins; Proteome; Proteomics; Published Comment; Records; Recruitment Activity; Research; Research Personnel; Scientist; Site; Societies; Solutions; South Carolina; Students; Technology; Thinking; Time; Training; Translating; Translations; Underrepresented Minority; United States; Universities; Validation; Virginia; Woman; abstracting; base; career; cell growth regulation; clinical application; clinical assay development; density; design; graduate student; handicapping condition; human disease; human tissue; improved; innovation; interest; medical schools; meetings; member; nervous system disorder; new technology; novel; operation; outcome forecast; posters; prognostic; programs; social; symposium; translational medicine; treatment strategy

DESCRIPTION (provided by applicant): We request partial funding support for operation of the 2011 Annual Meeting of the United States Human Proteome Organization (US-HUPO) entitled "Proteomics: New Developments and Grand Challenges", to be held March 20-23, 2011 in Raleigh, North Carolina. This meeting has been and continues to be a vital conference for the highly interdisciplinary scientific field of proteomics directed towards biological and clinical questions. US-HUPO is a unique meeting of scientists because it truly reflects the multiple disciplines, strategies, and technologies for which proteomics encompasses to enable this field to approach and solve sophisticated biomedical problems and provide perspective and accomplishments on how these findings can be translated into the clinic for diagnostic, prognostic and treatment purposes. The field is rich with diverse technological platforms including mass spectrometry, protein microarrays, biosensors, clinical assays, and biomarker discovery and validation. The first meeting of US-HUPO was in 2005 and what has evolved is a program that has provided the scientific foundation that has propelled the field of proteomics forward in rapid fashion. The conference is heavily attended and has always attracted first-rate speakers in this field. The 2011 Annual Meeting will again bring together an outstanding and diverse group of scientists at the forefront of proteomics. Invited speakers in the symposium will explicitly discuss applications relevant to a wide range of diseases including cardiovascular disease, cancer, and infectious diseases. The technological advances that have been made in the recent year are of critical importance to allow scientists to more effectively address biological problems and thus, this will also be a hallmark of the meeting. The topics chosen will educate participants on the latest, most effective technologies and methods, illustrate successful translation of these technologies into the clinic, and highlight new directions and grand challenges for the future of this field. Panel discussions will be held on key topics in order to encourage a robust dialogue between speakers and meeting participants to discuss critical goals for the future in proteomics, outline anticipated obstacles, and brainstorm solutions. This year US- HUPO will introduce a Business Meeting in the program to allow the participants to understand the mission and details of US-HUPO and thus allow for direct feedback from those in attendance to further improve the meeting. The poster sessions will also offer a more informal exchange of scientific ideas and advances. Ample time will be devoted to social venues for attendees to meet each other and establish new contacts and collaborations. Currently, 33% of the invited speakers are either women or members of minority groups and 33% are new investigators (Assistant/Associate Level). Attendance is expected to be 350-450 participants, including 100-150 students/post A docs. Registration is not restricted, and all interested persons may attend. A special effort will be made to recruit minority and industrial participants; the latter should be readily achievable given that Research Triangle Park is only 15 minutes from downtown Raleigh. Participants will present posters on new findings each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human disease. To emphasize this goal, over 20 poster presentations that complement the themes of the meeting will be selected for short oral presentations during the concurrent sessions. Finally, it is important to note that preceding the meeting, US-HUPO offer several Full-Day and Half-Day short courses on contemporary topics in proteomics. PUBLIC HEALTH RELEVANCE (provided by applicant): Funding is requested to support the 2011 Annual Meeting of the United States Human Proteome Organization (US-HUPO), whose mission is to promote scientific and educational activities to encourage the use of new technologies for analyzing proteins in human tissues and fluids, and model organisms, with the ultimate goal of developing critically needed methods for early diagnosis, prognosis of human diseases and new therapies for treating contemporary health problems that affect millions of people worldwide.

描述（由申请人提供）：我们请求为美国人类蛋白质组组织 (US-HUPO) 2011 年年会的运作提供部分资金支持，该年会题为“蛋白质组学：新发展和重大挑战”，该会议将于 2011 年 3 月 20 日至 23 日在北卡罗来纳州罗利举行。这次会议一直并将继续是针对生物和临床问题的蛋白质组学高度跨学科科学领域的一次重要会议。 US-HUPO 是一次独特的科学家会议，因为它真正反映了蛋白质组学所涵盖的多个学科、策略和技术，使该领域能够处理和解决复杂的生物医学问题，并就如何将这些发现转化为临床用于诊断、预后和治疗目的提供观点和成就。该领域拥有丰富的多样化技术平台，包括质谱、蛋白质微阵列、生物传感器、临床分析以及生物标志物发现和验证。 US-HUPO 的第一次会议于 2005 年举行，所发展的项目为推动蛋白质组学领域的快速发展提供了科学基础。会议出席人数众多，一直吸引着该领域的一流演讲者。 2011 年年会将再次汇聚处于蛋白质组学前沿的杰出且多元化的科学家群体。研讨会上的特邀演讲者将明确讨论与心血管疾病、癌症和传染病等多种疾病相关的应用。近年来取得的技术进步对于科学家更有效地解决生物问题至关重要，因此，这也将成为本次会议的一个标志。所选主题将向参与者介绍最新、最有效的技术和方法，展示这些技术如何成功转化为临床，并强调该领域未来的新方向和重大挑战。小组讨论将围绕关键主题进行，以鼓励演讲者和与会者之间进行强有力的对话，讨论蛋白质组学未来的关键目标，概述预期的障碍，并集思广益解决方案。今年US-HUPO将在项目中引入商务会议，让参与者了解US-HUPO的使命和细节，从而让与会人员直接反馈，进一步改进会议。海报会议还将提供更加非正式的科学思想和进展交流。将有充足的时间用于社交场所，供与会者见面并建立新的联系和合作。目前，受邀演讲者中有 33% 是女性或少数群体成员，33% 是新调查员（助理/副级别）。预计出席人数为 350-450 人，其中包括 100-150 名学生/A 博士后文档。报名不限，有兴趣者均可参加。将特别努力招募少数族裔和工业参与者；鉴于三角研究园距罗利市中心仅 15 分钟路程，后者应该很容易实现。参与者将每天下午展示新发现的海报。重要的是，这次会议为年轻研究人员提供了一个论坛，让他们了解基础科学探究与科学方法在设计人类疾病有效干预措施中的应用之间的联系。为了强调这一目标，将选择20多个与会议主题相辅相成的海报展示，在同期会议期间进行简短的口头报告。最后，值得注意的是，在会议之前，US-HUPO 提供了一些关于当代蛋白质组学主题的全日制和半日制短期课程。 公共健康相关性（由申请人提供）：请求资金支持美国人类蛋白质组组织 (US-HUPO) 2011 年年会，其使命是促进科学和教育活动，鼓励使用新技术分析人体组织和体液以及模式生物中的蛋白质，最终目标是开发人类疾病早期诊断、预后急需的方法和治疗当代健康的新疗法 影响全世界数百万人的问题。