2011 US-HUPO Conference -- Proteomics: New Developments and Grand Challenges

描述（由申请人提供）：我们要求为2011年3月20日至23日在北卡罗来纳州罗利举行的美国人类蛋白质组组织（US-HUPO）题为“蛋白质组学：新发展和重大挑战”的2011年年会提供部分资金支持。本次会议一直是并将继续是高度跨学科的蛋白质组学科学领域针对生物学和临床问题的重要会议。US-HUPO是一次独特的科学家会议，因为它真正反映了蛋白质组学所涵盖的多学科、策略和技术，使该领域能够接近和解决复杂的生物医学问题，并为如何将这些发现转化为临床诊断、预后和治疗目的提供了视角和成就。该领域拥有丰富的各种技术平台，包括质谱，蛋白质微阵列，生物传感器，临床分析和生物标志物发现和验证。US-HUPO的第一次会议是在2005年，它的发展是一个项目，它提供了科学基础，推动了蛋白质组学领域的快速发展。这次会议参加人数众多，总是能吸引这一领域的一流演讲者。2011年年会将再次汇集蛋白质组学前沿的杰出和多样化的科学家群体。研讨会的特邀演讲者将明确讨论与心血管疾病、癌症和传染病等广泛疾病相关的应用。近年来取得的技术进步对于让科学家更有效地解决生物学问题至关重要，因此，这也将是这次会议的一个标志。所选择的主题将向参与者介绍最新，最有效的技术和方法，说明这些技术成功转化为临床，并强调该领域未来的新方向和重大挑战。小组讨论将围绕关键主题举行，以鼓励演讲者和与会者之间进行强有力的对话，讨论蛋白质组学未来的关键目标，概述预期的障碍，并集思广益解决方案。今年，US-HUPO将在项目中引入商务会议，让与会者了解US-HUPO的使命和细节，从而允许与会者直接反馈，以进一步改善会议。海报会议还将提供更非正式的科学思想和进展交流。将有充足的时间用于社交场所，让与会者彼此见面并建立新的联系和合作。目前，33%的受邀演讲者是妇女或少数群体成员，33%是新的调查人员（助理/助理级）。预计出席人数为350-450人，其中包括100-150名学生/博士后。报名不受限制，所有感兴趣的人士均可参加。将作出特别努力，招募少数民族和工业参与者；后者应该很容易实现，因为三角研究公园距离罗利市中心只有15分钟的路程。参加者将于每天下午张贴有关新发现的海报。重要的是，会议为年轻的研究人员提供了一个论坛，让他们看到基础科学探究与科学方法应用于设计有效的人类疾病干预措施之间的联系。为了强调这一目标，将在同期会议期间选出20多份与会议主题相辅相成的海报报告作为简短的口头报告。最后，值得注意的是，在会议之前，US-HUPO提供了几个关于蛋白质组学当代主题的全天和半天短期课程。

DESCRIPTION (provided by applicant): We request partial funding support for operation of the 2011 Annual Meeting of the United States Human Proteome Organization (US-HUPO) entitled "Proteomics: New Developments and Grand Challenges", to be held March 20-23, 2011 in Raleigh, North Carolina. This meeting has been and continues to be a vital conference for the highly interdisciplinary scientific field of proteomics directed towards biological and clinical questions. US-HUPO is a unique meeting of scientists because it truly reflects the multiple disciplines, strategies, and technologies for which proteomics encompasses to enable this field to approach and solve sophisticated biomedical problems and provide perspective and accomplishments on how these findings can be translated into the clinic for diagnostic, prognostic and treatment purposes. The field is rich with diverse technological platforms including mass spectrometry, protein microarrays, biosensors, clinical assays, and biomarker discovery and validation. The first meeting of US-HUPO was in 2005 and what has evolved is a program that has provided the scientific foundation that has propelled the field of proteomics forward in rapid fashion. The conference is heavily attended and has always attracted first-rate speakers in this field. The 2011 Annual Meeting will again bring together an outstanding and diverse group of scientists at the forefront of proteomics. Invited speakers in the symposium will explicitly discuss applications relevant to a wide range of diseases including cardiovascular disease, cancer, and infectious diseases. The technological advances that have been made in the recent year are of critical importance to allow scientists to more effectively address biological problems and thus, this will also be a hallmark of the meeting. The topics chosen will educate participants on the latest, most effective technologies and methods, illustrate successful translation of these technologies into the clinic, and highlight new directions and grand challenges for the future of this field. Panel discussions will be held on key topics in order to encourage a robust dialogue between speakers and meeting participants to discuss critical goals for the future in proteomics, outline anticipated obstacles, and brainstorm solutions. This year US- HUPO will introduce a Business Meeting in the program to allow the participants to understand the mission and details of US-HUPO and thus allow for direct feedback from those in attendance to further improve the meeting. The poster sessions will also offer a more informal exchange of scientific ideas and advances. Ample time will be devoted to social venues for attendees to meet each other and establish new contacts and collaborations. Currently, 33% of the invited speakers are either women or members of minority groups and 33% are new investigators (Assistant/Associate Level). Attendance is expected to be 350-450 participants, including 100-150 students/post A docs. Registration is not restricted, and all interested persons may attend. A special effort will be made to recruit minority and industrial participants; the latter should be readily achievable given that Research Triangle Park is only 15 minutes from downtown Raleigh. Participants will present posters on new findings each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human disease. To emphasize this goal, over 20 poster presentations that complement the themes of the meeting will be selected for short oral presentations during the concurrent sessions. Finally, it is important to note that preceding the meeting, US-HUPO offer several Full-Day and Half-Day short courses on contemporary topics in proteomics. PUBLIC HEALTH RELEVANCE (provided by applicant): Funding is requested to support the 2011 Annual Meeting of the United States Human Proteome Organization (US-HUPO), whose mission is to promote scientific and educational activities to encourage the use of new technologies for analyzing proteins in human tissues and fluids, and model organisms, with the ultimate goal of developing critically needed methods for early diagnosis, prognosis of human diseases and new therapies for treating contemporary health problems that affect millions of people worldwide.