2011 Vascular Cell Biology Gordon Research Conference

描述(由申请者提供)：申请资助将于2011年2月20-25日在加利福尼亚州文图拉举行的“血管生物学”戈登研究会议。会议将涵盖一系列主题，包括血管系统的发育和模式、血管壁细胞之间的通讯机制、血管形态发生和疾病中的机械转导、细胞内信号以及血管的通透性和维持。会议将汇集代表各种学科、方法和系统的发言者、讨论者和与会者。会议规模小，气氛非正式，将促进讨论和互动。我们对血管生物学调节机制的理解取得了重大进展，特别是对细胞间通信和各种疾病中的血管障碍的新见解，使这次会议特别及时。 公共卫生相关性：本次会议的主要目标是加快研究血管系统在健康和疾病方面的发展、模式和调节的研究人员的进展。开发血管系统疾病的治疗方法，如心脏病发作和中风，需要了解控制其功能的细胞相互作用和调节。血管功能障碍也是癌症和免疫疾病的一个主要因素，因此，对血管系统细胞生物学的了解的进展将影响人类健康的主要领域。

DESCRIPTION (provided by applicant): Funds are requested to support the Gordon Research Conference on "Vascular Biology" to be held Feb 20-25, 2011 in Ventura, CA. The conference will cover a range of topics including development and patterning of the vascular system, mechanisms of communication between cells in the vascular wall, mechanotransduction in vascular morphogenesis and disease, intracellular signaling, and vascular permeability and maintenance. The meeting will bring together speakers, discussants and participants who represent a wide range of disciplines, approaches and systems. The small size of the conference and the informal atmosphere will facilitate discussion and interactions. Major advances in our understanding of regulatory mechanisms in vascular biology, especially new insights into cell-cell communication and vascular disturbances in various diseases make this a particularly timely meeting. PUBLIC HEALTH RELEVANCE: The main goal of this meeting is to accelerate progress by researchers who are studying the development, patterning and regulation of the vascular system, in both health and disease. Developing treatments for diseases of the vascular system such as heart attack and stroke requires understanding the cellular interactions and regulation that control its function. Vascular malfunction is also a major contributing factor in cancer and immune diseases, thus, advances in understanding the cell biology of the vascular system will impact major areas of human health.