Nutritional & Behavioral Cancer Prevention in a Multiethnic Population

营养

• 批准号: 8396589
• 负责人: GERTRAUD MASKARINEC
• 金额: $ 10.57万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-02-08 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8396589
• 关键词: Address; Advisory Committees; Applications Grants; Asians; Basic Science; Behavior; Behavior Therapy; Behavioral; Behavioral Genetics; Behavioral Sciences; Biological Markers; Biometry; Blood; Cancer Burden; Cancer Etiology; Cancer Family; Cancer Research Center of Hawaii; Cancer Research Network; Cancer Survivorship; Cancer-Predisposing Gene; Cohort Studies; Collaborations; Colorectal Cancer; Computerized Medical Record; Cooperative Family Registry; Data; Databases; Development; Development Plans; Diagnosis; Dietary Assessment; Discipline; Early Diagnosis; Eating Behavior; Education; Educational Curriculum; Endometrial Carcinoma; Environment; Epidemiology; Epigenetic Process; Exposure to; Faculty; Family-Based Registry; Food; Genetic; Genetic Research; Goals; Grant; Grant Review; Hawaii; Healthcare Systems; Human Papillomavirus; Incidence; Individual; Institution; International; Intervention; Investigation; Journals; Knowledge; Learning; Life Style; Link; Malignant Neoplasms; Malignant neoplasm of lung; Malignant neoplasm of ovary; Manuscripts; Mentors; Molecular; Monitor; NCI Center for Cancer Research; Nutritional; Nutritional Study; Pacific Island Americans; Persons; Population; Population Sciences; Population Study; Postdoctoral Fellow; Predisposition; Preparation; Prevention Research; Prevention strategy; Primary Prevention; Prognostic Marker; Recurrence; Research; Research Design; Research Personnel; Research Project Grants; Resources; Risk Behaviors; Risk Factors; Rotation; Sampling; Scientist; Screening for cancer; Series; Southwest Oncology Group; Specimen; Strategic Planning; Tissues; Training; Training Program for Cancer Prevention and Control Scientists (R25); Training Programs; Tumor Tissue; United States; Universities; Woman; Work; Writing; aging population; base; cancer prevention; cancer risk; career; career development; cohort; design; experience; gene environment interaction; innovation; meetings; member; mortality; multidisciplinary; nutrition; nutritional epidemiology; population based; post-doctoral training; programs; prospective; repository; skills; statistics; symposium; tumor; tumor registry

DESCRIPTION (provided by applicant): With an aging population, the burden of cancer in the US keeps increasing despite improvements in primary prevention, early detection, and treatment. As research in cancer prevention has grown in sophistication and complexity, the need for multidisciplinary training in the population sciences is greater than ever. The purpose of this training program is to prepare young scientists who will elucidate the causes of cancer and develop strategies to reduce cancer incidence and mortality. This Cancer Education and Career Development Program (CECDP) will focus on nutritional epidemiology and behavioral cancer prevention in a multiethnic population. The program based at the Cancer Research Center at the University of Hawaii will be led by population researchers representing the disciplines of nutrition, behavioral sciences, epidemiology, and biostatistics and actively engaged in conducting population science research. The program will build on several unique resources, such as three prospective cohorts, access to consortia, a nutritional data base designed for multiethnic populations, the Hawaii Tumor Registry, and Kaiser Permanente Hawaii. The specific aims of the proposed postdoctoral program in Hawaii are to train postdoctoral fellows to function as independent researchers in a multidisciplinary environment focusing on nutritional epidemiology and behavioral cancer prevention in a multiethnic population; to provide a specialized curriculum in biostatistics, nutrition, epidemiology, behavioral sciences, biomarkers, and genetics for research in multiethnic populations; and to offer extensive applied experience in conducting transdisciplinary cancer prevention research, designing new research projects, and writing grant proposals and manuscripts. Postdoctoral trainees will complete a two-to three-year program that will include multiple mentors, transdisciplinary research experiences, and educational opportunities. The core requirements of this CECDP consist of a specialized curriculum, rotations providing practical research experience, a seminar series addressing basic research requirements and skills, research seminars and journal clubs at CRCH, scientific meetings and conferences, formal course work including a degree option at the University of Hawaii, training courses at NCI and other institutions, and a mock grant review. Each trainee will develop individualized education and career development plans based on the prior academic preparation and career goals. The specialized curriculum will include four major components designed as preparation to work with multiethnic study populations: biostatistics, nutrition, behavioral sciences, and biomarker analysis. This research environment, together with the proposed program plan, provides an ideal opportunity to train high-quality collaborative cancer prevention scientists. With increasing ethnic diversity of the population in the United States, skills learned in our postdoctoral training will enable young researchers to explore issues in cancer etiology and survivorship in populations with diverse ethnic backgrounds and to develop interventions that are tailored to individuals with different eating behaviors and cultural norms.

描述(申请人提供)：随着人口老龄化，美国癌症的负担不断增加，尽管在初级预防、早期发现和治疗方面有所改善。随着癌症预防研究的复杂性和复杂性的增长，人口科学中的多学科培训的需求比以往任何时候都更大。该培训计划的目的是培养年轻的科学家，他们将阐明癌症的原因，并制定降低癌症发病率和死亡率的策略。这项癌症教育和职业发展计划(CECDP)将重点放在多种族人群的营养流行病学和行为癌症预防上。这项以夏威夷大学癌症研究中心为基地的项目将由代表营养、行为科学、流行病学和生物统计学学科的人口研究人员领导，并积极参与人口科学研究。该计划将建立在几个独特资源的基础上，例如三个预期队列、获得财团的机会、为多种族人口设计的营养数据库、夏威夷肿瘤登记中心和夏威夷凯撒永久医院。夏威夷拟议的博士后项目的具体目标是培养博士后研究员在多学科环境中发挥独立研究人员的作用，重点是多民族人口中的营养流行病学和行为癌症预防；为多民族人口的研究提供生物统计学、营养学、流行病学、行为科学、生物标记物和遗传学的专门课程；并在进行跨学科癌症预防研究、设计新的研究项目以及撰写拨款提案和手稿方面提供广泛的应用经验。博士后实习生将完成一个为期两到三年的计划，其中将包括多名导师、跨学科研究经验和教育机会。CECDP的核心要求包括一门专门的课程，提供实践研究经验的轮换，一系列涉及基本研究要求和技能的研讨会，研究 CRCH的研讨会和期刊俱乐部，科学会议和会议，正式课程工作，包括夏威夷大学的学位选项，NCI和其他机构的培训课程，以及模拟拨款审查。每个学员将根据先前的学业准备和职业目标制定个性化的教育和职业发展计划。专业课程将包括四个主要组成部分，旨在为多种族研究人群做准备：生物统计学、营养学、行为科学和生物标记物分析。这一研究环境与拟议的项目计划一起，为培养高素质的协作式癌症预防科学家提供了理想的机会。随着美国人口的种族多样性日益增加，我们在博士后培训中学到的技能将使年轻研究人员能够探索癌症病因和不同种族背景人口的生存问题，并开发针对不同饮食行为和文化规范的个人量身定做的干预措施。

项目成果

Diabetes and urothelial cancer risk: the Multiethnic Cohort study.

• DOI: 10.1016/j.canep.2011.02.014
• 发表时间: 2011-12
• 期刊: CANCER EPIDEMIOLOGY
• 影响因子: 2.6
• 作者: Woolcott, Christy G.;Maskarinec, Gertraud;Haiman, Christopher A.;Henderson, Brian E.;Kolonel, Laurence N.
• 通讯作者: Kolonel, Laurence N.

The reasons for betel-quid chewing scale: assessment of factor structure, reliability, and validity.

• DOI: 10.1186/1472-6831-14-62
• 发表时间: 2014-06-03
• 期刊: BMC oral health
• 影响因子: 2.9
• 作者: Little MA;Pokhrel P;Murphy KL;Kawamoto CT;Suguitan GS;Herzog TA
• 通讯作者: Herzog TA

Ethnic differences in weight gain and diabetes risk: the Multiethnic Cohort Study.

体重增加和糖尿病风险的种族差异：多种族队列研究。

• DOI: 10.1016/j.diabet.2010.10.005
• 发表时间: 2011
• 期刊: Diabetes & metabolism
• 影响因子: 7.2
• 作者: Morimoto,Y;Schembre,SM;Steinbrecher,A;Erber,E;Pagano,I;Grandinetti,A;Kolonel,LN;Maskarinec,G
• 通讯作者: Maskarinec,G

The Betel Quid Dependence Scale: replication and extension in a Guamanian sample.

• DOI: 10.1016/j.drugalcdep.2014.02.022
• 发表时间: 2014-05-01
• 期刊: DRUG AND ALCOHOL DEPENDENCE
• 影响因子: 4.2
• 作者: Herzog, Thaddeus A.;Murphy, Kelle L.;Little, Melissa A.;Suguitan, Gil S.;Pokhrel, Pallav;Kawamoto, Crissy T.
• 通讯作者: Kawamoto, Crissy T.

Psychometric properties and construct validity of the Weight-Related Eating Questionnaire in a diverse population.

• DOI: 10.1038/oby.2011.96
• 发表时间: 2011-12
• 期刊: OBESITY
• 影响因子: 6.9
• 作者: Schembre, Susan M.;Geller, Karly S.
• 通讯作者: Geller, Karly S.