Washington University Institute of Clinical and Translational Sciences

这个CTSA更新应用程序是建立在研究基础设施，培训计划和合作伙伴关系 我们在第一个资助期内，通过建立临床和转化研究所， 这给华盛顿带来了重大的文化和组织变革 圣路易斯大学及其合作机构之间前所未有的合作，包括BJC 保健，巴恩斯犹太医院，圣路易斯儿童医院，圣刘易斯大学， 密苏里州-圣路易斯，南伊利诺伊大学爱德华兹维尔，巴恩斯-犹太护理学院戈德法布 圣路易斯药学院（St. Louis College of Pharmacy）此应用程序的总体目标是促进 将科学发现转化为人类健康的改善。 我们的具体目标将改变我们的研究支持基础设施，以促进多学科的临床和 转化研究，扩大和加强临床和转化研究教育计划，以及 促进与区域和国家伙伴的交流和合作研究。新举措 包括3个新的交叉科学主题，我们的信息和通信技术资源最有可能导致 高影响力的临床研究及其随后转化为临床实践： 遗传/基因组研究纳入临床研究和实践，加速开发和评估 新疗法，并进行比较有效性和传播和实施 研究，以促进研究成果转化为实践。 为了确保ICTS的持续成功，WU在空间和环境方面做出了重大承诺。 金融支持巴恩斯犹太医院和圣路易斯儿童医院，我们的学术医院合作伙伴， 和我们的附属卫生系统BJC HealthCare也做出了实质性承诺， ICTS的临床和转化研究活动。这种机构支持，加上 我们在过去四年中开始的计划和合作，确保ICTS将继续 在临床和转化科学方面做出突出贡献。

This CTSA renewal application is built on the research infrastructure, training programs, and partnerships we established in the first grant period, through creation ofthe Institute for Clinical and Translational Sciences (ICTS), which brought about significant cultural and organizational changes at Washington University in St. Louis and unprecedented collaboration between its partner institutions, including BJC HealthCare, Barnes-Jewish Hospital, St. Louis Children's Hospital, Saint Louis University, University of Missouri - St. Louis, Southern Illinois University Edwardsville, Goldfarb School of Nursing at Barnes-Jewish College, and the St. Louis College of Pharmacy. The overall goal of this application is to promote the translation of scientific discoveries into improvements in human health. Our specific aims will transform our research support infrastructure to foster multidisciplinary clinical and translational research, expand and enhance clinical and translational research education programs, and promote communication and collaborative research with regional and national partners. New initiatives include 3 new cross-cutting scientific themes where the resources of our ICTS are most likely to result in high-impact clinical research and its subsequent translation into clinical practice: translating the findings of genetic/genomic research into clinical research and practice, accelerating the development and evaluation of new therapeutics, and conducting comparative effectiveness and dissemination and implementation research to improve the transfer of research into practice. To ensure the continued success ofthe ICTS, WU has made significant commitments of space and financial support. Barnes-Jewish Hospital and St. Louis Children's Hospital, our academic hospital partners, and BJC HealthCare, our affiliated health system, have also made substantial commitments to suppport the clinical and translational research activities ofthe ICTS. This institutional support, combined with the programs and collaborations we have started in the past four years, ensure that the ICTS will continue to make outstanding contributions in clinical and translational science.