Washington University Institute of Clinical and Translational Sciences

华盛顿大学临床与转化科学研究所

• 批准号: 9474890
• 负责人: Bradley A Evanoff
• 金额: $ 943.68万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-19 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9474890
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Contact PD/PI: Evanoff, Bradley A Overall Component 7. Project Summary/Abstract: The Washington University (WU) Institute of Clinical and Translational Sciences (ICTS) has transformed clinical and translational science and research education in our region, and fostered productive scientific collaborations with our hub partner institutions University of Missouri-Columbia, Saint Louis University, St. Louis College of Pharmacy, BJC HealthCare, Barnes Jewish Hospital, and St. Louis Children's Hospital. The ICTS now proposes innovative aims that align well with the goals of the CTSA network, and will together catalyze discovery and advance research findings into real-world implementation to improve health and health care. 1. Provide interdisciplinary programs to develop, promote, and retain highly qualified and diverse faculty, trainees, and staff who can translate scientific discoveries into action. We will tailor our efforts to the needs of individuals, promote formation of transdisciplinary, inter-institutional, and inter-hub teams, rigorously assess our programs, and draw on our institutional and regional strengths in genomics, dissemination and implementation, and entrepreneurship. WORKFORCE DEVELOPMENT 2. Facilitate research that is designed for implementation by engaging diverse communities and stakeholders in collaborative teams at all stages of the translational research process. We will partner with patient advocates, propel the science of community and stakeholder engagement, break down barriers to allow integration of research findings into clinical practice, and capitalize on our local entrepreneurial ecosystem to apply discoveries to improve community health. COLLABORATION AND ENGAGEMENT 3. Integrate research across the lifespan and promote translational science within complex populations. The ICTS will address health disparities and differences in disease manifestations across different ages and among special populations, address both urban and rural populations, catalyze formation of transdisciplinary teams, and evaluate the clinical, community, and entrepreneurial outcomes of our researchers' work. INTEGRATION 4. Drive innovation, quality, and efficiency in the translational research, by using best practices and streamlined institutional processes to support high quality multi-center clinical trials and developing new methodological approaches to facilitate translational research. METHODS AND PROCESSES 5. Apply innovative informatics solutions to improve quality and efficiency at every stage of translational research, and create an ecosystem that integrates diverse data and facilitates the interoperability, use, and reuse of digital assets. INFORMATICS Successful completion of these aims will transform regional research, dissemination, and workforce development and will apply the considerable resources of WU and its partners to national CTSA goals to advance clinical and translational science and improve human health. Project Summary/Abstract Page 375 Contact PD/PI: Evanoff, Bradley A Overall Component 8.

联系PD/PI：Evanoff，布拉德利A 总体组件 7.项目概要/摘要： 华盛顿大学（WU）临床和转化科学研究所（ICTS）已经转变为 在我们地区的临床和转化科学和研究教育，并培养了生产性的科学 与我们的中心合作伙伴机构密苏里大学-哥伦比亚大学，圣刘易斯大学，圣路易斯大学， 路易斯药学院、BJC医疗保健、巴恩斯犹太医院和圣路易斯儿童医院。的 信通技术服务现在提出了与CTSA网络的目标相一致的创新目标， 促进发现并将研究成果推进到现实世界的实施中，以改善健康和健康 在乎 1.提供跨学科课程，以发展，促进和保留高素质和多样化 教师，学员和工作人员谁可以将科学发现转化为行动。我们将调整我们的努力， 个人的需求，促进跨学科，跨机构和跨枢纽团队的形成， 严格评估我们的项目，并利用我们在基因组学方面的机构和地区优势， 传播和执行以及创业精神。劳动力发展 2.促进旨在通过吸引不同社区参与实施的研究， 在翻译研究过程的各个阶段的合作团队的利益相关者。我们将合作 与患者倡导者一起，推动社区和利益相关者参与的科学，打破障碍， 允许将研究成果融入临床实践，并利用我们当地的企业 生态系统应用新发现来改善社区健康。合作与参与 3.整合整个生命周期的研究，并在复杂的环境中促进转化科学 人口。信息和通信技术将解决健康差距和疾病表现的差异， 不同年龄和特殊人群，解决城市和农村人口， 跨学科团队，并评估我们的临床，社区和创业成果 研究人员的工作。一体化 4.通过使用最佳实践， 简化机构流程，以支持高质量的多中心临床试验，并开发新的 方法论的方法，以促进翻译研究。方法和过程 5.应用创新的信息学解决方案，提高每个阶段的质量和效率 转化研究，并创建一个生态系统，整合不同的数据，并促进 数字资产的互操作性、使用和重用。信息学 成功完成这些目标将改变区域研究、传播和劳动力 发展并将利用WU及其合作伙伴的大量资源来实现国家CTSA目标， 推进临床和转化科学，改善人类健康。 项目摘要/摘要第375页 联系PD/PI：Evanoff，布拉德利A 总体组件 8.