Proteomics, Metabolomics and Lipidomics Core

蛋白质组学、代谢组学和脂质组学核心

基本信息

  • 批准号:
    8234059
  • 负责人:
  • 金额:
    $ 49.7万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2011
  • 资助国家:
    美国
  • 起止时间:
    2011-03-01 至 2014-02-28
  • 项目状态:
    已结题

项目摘要

The PNW RCE Proteomics, Metabolomics, and Lipidomics (PML) Core provides the resources required for the parallel application of proteomic, metabolomic, and lipidomic analyses to diverse sample sets provide by the RCE collaborators. The integration of data generated by these PML Core approaches with the genomic analyses performed by individual Projects and sub-projects (Project 3 (P01) Dr. Michael Katze, Project 4 (P01) Dr. Michael Gale, and Project 5 (R01) Dr. Fred Heffron), creates a unique opportunity to model disease-related pathways (see Biostatistics and Bioinformatics Core) associated with infection by severe acute respiratory syndrome (SARS) virus, flu virus, Ebola virus, West Nile virus (WNV), Dengue virus (DENV), and Francisella novidica. The PML Core will leverage ongoing technical advances in proteomics (including phosphoproteomics), metabolomics, lipidomics, and informatics resources available at PNNL to generate unique suites of systems biology data by performing high throughput, sensitive, and reproducible protein, metabolite, and lipid abundance measurements on comparative and longitudinal samples for iterative cycles of computational modeling and experimental validation. The PML Core provides both resources and support through multiple stages of proteomics, metabolomics, and lipidomics data acquisition, from construction/augmentation of reference accurate mass and time tag (AMT) tag databases through comparative quantitative analyses. Peptide and lipid coverage in AMT tag databases will be enhanced by advanced liquid chromatography separation methods pioneered at PNNL to reduce sample complexity. In the RCE the PML Core will leverage established and ongoing technological advancements at PNNL accomplished under other support in order to perform the large-scale measurements demanded by the Center collaborations.
PNW RCE蛋白质组学、代谢组学和脂质组学(PML)核心提供了所需的资源

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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RICHARD D SMITH其他文献

RICHARD D SMITH的其他文献

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{{ truncateString('RICHARD D SMITH', 18)}}的其他基金

Experimental Core
实验核心
  • 批准号:
    10213204
  • 财政年份:
    2018
  • 资助金额:
    $ 49.7万
  • 项目类别:
Proteomics, Metabolomics and Lipidomics
蛋白质组学、代谢组学和脂质组学
  • 批准号:
    8580047
  • 财政年份:
    2013
  • 资助金额:
    $ 49.7万
  • 项目类别:
WORKSHOP AND TRAINING ACTIVITIES
研讨会和培训活动
  • 批准号:
    8365463
  • 财政年份:
    2011
  • 资助金额:
    $ 49.7万
  • 项目类别:
APPROACHES FOR PROTEIN MODIFICATIONS, INTERACTIONS, & SPATIAL & QUANTITATIVE DYN
蛋白质修饰、相互作用的方法,
  • 批准号:
    8365459
  • 财政年份:
    2011
  • 资助金额:
    $ 49.7万
  • 项目类别:
HIV PROTEOMIC CENTER FOR HOST-VIRAL RESPONSE CHARACTERIZATION
HIV 宿主病毒反应表征蛋白质组学中心
  • 批准号:
    8357610
  • 财政年份:
    2011
  • 资助金额:
    $ 49.7万
  • 项目类别:
HIV PROJECT
艾滋病项目
  • 批准号:
    8365479
  • 财政年份:
    2011
  • 资助金额:
    $ 49.7万
  • 项目类别:
HIV PROJECT
艾滋病项目
  • 批准号:
    8170720
  • 财政年份:
    2010
  • 资助金额:
    $ 49.7万
  • 项目类别:
WORKSHOP AND TRAINING ACTIVITIES
研讨会和培训活动
  • 批准号:
    8170700
  • 财政年份:
    2010
  • 资助金额:
    $ 49.7万
  • 项目类别:
HIV PROTEOMIC CENTER FOR HOST-VIRAL RESPONSE CHARACTERIZATION
HIV 宿主病毒反应表征蛋白质组学中心
  • 批准号:
    8172780
  • 财政年份:
    2010
  • 资助金额:
    $ 49.7万
  • 项目类别:
TECH R&D CORE SUPPORT FOR AIDS RESEARCH
技术研发
  • 批准号:
    8170722
  • 财政年份:
    2010
  • 资助金额:
    $ 49.7万
  • 项目类别:

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合作研究:OPUS:排列生物测定:综合生态学和进化中的数据分析
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用于学龄前儿童视力筛查的光学生物测量方法
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    17K13249
  • 财政年份:
    2017
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Whole Eye Biometry System
全眼生物测量系统
  • 批准号:
    9274928
  • 财政年份:
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全球背景下海洋缺氧事件 1a 和 1d 期间钙质超微化石的高分辨率生物测量和形态特征
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    241525448
  • 财政年份:
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    $ 49.7万
  • 项目类别:
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BIOMETRY CORE
生物测定核心
  • 批准号:
    8360347
  • 财政年份:
    2011
  • 资助金额:
    $ 49.7万
  • 项目类别:
BIOMETRY CORE FACILITY
生物测定核心设施
  • 批准号:
    8167869
  • 财政年份:
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Biometry
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  • 批准号:
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Biometry and Microarray Core
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    7659698
  • 财政年份:
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    $ 49.7万
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