Core B: Neutron Physics and Instrumentation

核心 B：中子物理与仪器

• 批准号: 8374899
• 负责人: DAVID WORCESTER
• 金额: $ 22.09万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8374899
• 关键词: Action Potentials; Cardiac Myocytes; Cell membrane; Defect; Disease; Elements; Grant; Heart Diseases; Individual; Ion Channel Gating; Ions; Laboratories; Lipid Bilayers; Maryland; Measurement; Membrane; Methods; National Center for Research Resources; Nerve; Neuromuscular Diseases; Neutron Diffraction; Neutrons; Physics; Potassium Channel; Production; Reporting; Research; Research Support; Scientist; Solutions; Source; Students; Time; Training Support; Wages; Work; experience; instrument; instrumentation; member; novel; programs; research study; response; sensor; success; voltage

Core B provides support for the use by Program Project scientists of neutron scattering instruments at the NIST Center for Neutron Research (NCNR) in Gaithersburg, Maryland. The success of the Program Project, entitled Making Sense of Voltage Sensors, depends almost entirely on the use of neutron diffraction and reflectivity measurements to determine the disposition of potassium channels and their voltage sensors in lipid bilayer membranes. The specific aim of Core B is to provide technical and training support at the NCNR for Program scientists using neutron scattering instruments, particularly the Advanced Neutron Diffractometer/Reflectometer (AND/R). Technical and training support will be provided by Dr. David Worcester, who is one of the early pioneers of membrane neutron diffraction. Serving as the senior neutron scientist, he will be stationed full-time at the NCNR to work closely with Project scientists to help them plan, execute, and analyze neutron scattering experiments. He will report to and work closely with the Program Director to assure the timely planning and execution of the neutron scattering work proposed in Projects 2 and 3.

核心B为项目科学家使用中子散射仪器提供了支持