Core B: Neutron Physics and Instrumentation

核心 B：中子物理与仪器

• 批准号: 8435420
• 负责人: DAVID WORCESTER
• 金额: $ 21.36万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2015-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8435420
• 关键词: Action Potentials; Cardiac Myocytes; Cell membrane; Defect; Disease; Elements; Grant; Heart Diseases; Individual; Ion Channel Gating; Ions; Laboratories; Lipid Bilayers; Maryland; Measurement; Membrane; Methods; National Center for Research Resources; Nerve; Neuromuscular Diseases; Neutron Diffraction; Neutrons; Physics; Potassium Channel; Production; Reporting; Research; Research Support; Scientist; Solutions; Source; Students; Time; Training Support; Wages; Work; experience; instrument; instrumentation; member; novel; programs; research study; response; sensor; success; voltage

Core B provides support for the use by Program Project scientists of neutron scattering instruments at the NIST Center for Neutron Research (NCNR) in Gaithersburg, Maryland. The success of the Program Project, entitled Making Sense of Voltage Sensors, depends almost entirely on the use of neutron diffraction and reflectivity measurements to determine the disposition of potassium channels and their voltage sensors in lipid bilayer membranes. The specific aim of Core B is to provide technical and training support at the NCNR for Program scientists using neutron scattering instruments, particularly the Advanced Neutron Diffractometer/Reflectometer (AND/R). Technical and training support will be provided by Dr. David Worcester, who is one of the early pioneers of membrane neutron diffraction. Serving as the senior neutron scientist, he will be stationed full-time at the NCNR to work closely with Project scientists to help them plan, execute, and analyze neutron scattering experiments. He will report to and work closely with the Program Director to assure the timely planning and execution of the neutron scattering work proposed in Projects 2 and 3.

核心B为计划项目科学家使用中子散射仪器提供支持， 位于马里兰州盖瑟斯堡的NIST中子研究中心（NCNR）。项目的成功， 题为“电压传感器的意义”的论文，几乎完全依赖于中子衍射的使用， 反射率测量，以确定钾通道及其电压传感器在 脂双层膜核心项目B的具体目标是为全国核裁军委员会提供技术和培训支持 对于使用中子散射仪器的计划科学家，特别是高级中子 衍射仪/反射仪（AND/R）。大卫博士将提供技术和培训支持 他是膜中子衍射的早期开拓者之一。作为高级中子 作为一名科学家，他将全职驻扎在NCNR，与项目科学家密切合作，帮助他们计划， 执行和分析中子散射实验。他将向该计划汇报并与该计划密切合作 主任确保及时规划和执行项目2中建议的中子散射工作 和3.