North Dakota INBRE: Health and the Environment

北达科他州 INBRE：健康与环境

• 批准号: 8075420
• 负责人: Donald A. Sens
• 金额: $ 315.21万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-24 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8075420
• 关键词: North; Dakota; INBRE; Health; Environment

DESCRIPTION (provided by applicant): The North Dakota INBRE has succeeded beyond all reasonable expectations in fulfilling the IDeA program's goal of establishing an undergraduate research culture in the state's primarily undergraduate institutions (PUIs). Furthermore, each of the four PUIs in North Dakota have developed a culture capable of sustaining and enhancing these INBRE-sponsored undergraduate research programs. The ND INBRE has also advanced these efforts into the Native American community with the successful establishment of a genetics based, undergraduate-driven research program on pre-eclampsia at Turtle Mountain Community College. An introduction to research course has recently been developed by Native American faculty for the Cankdeska Cikana Community College, the ND INBRE has taken the lead in funding and stabilizing the K-12 portion of the Indians into Medicine Program. This program produces over 25% of the Nation's Native American physicians. Evidence is accumulating that the ND INBRE undergraduate research programs are having an impact on the pipeline of undergraduates entering biomedical research. A focused goal of ND INBRE in the coming year will be to develop bioinformatics beyond wire and library resources. Aim 1: To Continue to Support and Enhance the Outstanding Undergraduate Research Programs. Aim 2: To Continue to Support and Expand Efforts to Engage Native American Students in Undergraduate Research. Aim 3: To Continue to Support the INMED Summer Academy and Pathways Program. Aim 4: To Continue Support for a Previously Established Proteomics Core Facility and Continue Development of a Metal Analysis Core. To Initiate a Cutting-Edge Bioinformatics Program. Aim 5: To Establish a Community-Based Participatory Research Core. Aim 6: The Development of a Network that Encourages Scientific and Professional Interactions Among the Partners and Enhances the Pipeline of Students Entering Biomedical and Behavioral Research. PUBLIC HEALTH RELEVANCE (provided by applicant): The partners of the ND INBRE can state that all undergraduates in the State's PUIs, that were qualified and desired an undergraduate research experience in science, have been afforded this career-building opportunity. Furthermore, each of the four PUIs in North Dakota have developed a culture capable of sustaining and enhancing these INBRE-sponsored undergraduate research programs, all of which offer year-long, in-institution, participation in the undergraduate research enterprise.

描述（由申请人提供）：北达科他州INBRE已经成功地超越了所有合理的期望，实现了IDEA计划的目标，即在该州主要的本科院校（PUI）建立本科研究文化。此外，北达科他州的四个PUI都已经形成了一种能够维持和加强这些INBRE-sponsored本科研究计划的文化。ND INBRE还将这些努力推进到美洲原住民社区，成功建立了一个基于遗传学的，本科生驱动的关于海龟山社区学院先兆子痫的研究计划。最近，美国土著教师为Cankdeska Cikana社区学院开发了一个研究课程介绍，ND INBRE在资助和稳定K-12部分的印第安人进入医学计划方面发挥了带头作用。该计划产生了全国25%以上的美洲原住民医生。越来越多的证据表明，ND INBRE的本科研究项目正在对进入生物医学研究的本科生的管道产生影响。ND INBRE在未来一年的一个重点目标将是开发超越电线和图书馆资源的生物信息学。 目标1：继续支持和加强优秀的本科生研究计划。 目标2：继续支持和扩大努力，让美国原住民学生参与本科研究。 目标3：继续支持INMED暑期学院和途径方案。 目标4：继续支持先前建立的蛋白质组学核心设施， 开发金属分析核心。启动前沿生物信息学项目。 目标5：建立以社区为基础的前瞻性研究核心。 目标六：网络的发展，鼓励合作伙伴之间的科学和专业互动，并加强学生进入生物医学和行为研究的管道。 公共卫生相关性（由申请人提供）：ND INBRE的合作伙伴可以声明，该州PUI的所有本科生都有资格并希望获得科学本科生研究经验，已经获得了这个职业建设机会。此外，北达科他州的四个PUI都已经形成了一种能够维持和加强这些INBRE-sponsored本科研究项目的文化，所有这些项目都提供为期一年的，在机构内，参与本科研究企业。

项目成果

Comparative analysis of de novo transcriptome assembly.

从头转录组组件的比较分析。

• DOI: 10.1007/s11427-013-4444-x
• 发表时间: 2013-03
• 期刊: Science China. Life sciences
• 作者: Clarke K;Yang Y;Marsh R;Xie L;Zhang KK
• 通讯作者: Zhang KK

MINERALS IN THE HUMAN BODY: Erionite and offretite from the Killdeer Mountains, Dunn County, North Dakota, U.S.A.

人体中的矿物质：来自美国北达科他州邓恩县 Killdeer 山脉的毛沸石和菱沸石

• DOI: 10.2138/am.2014.4567
• 发表时间: 2014
• 期刊: The American mineralogist
• 作者: Saini-Eidukat,Bernhardt;Triplett,JasonW
• 通讯作者: Triplett,JasonW

Metallothionein isoform 3 expression in human skin, related cancers and human skin derived cell cultures.

金属硫蛋白亚型 3 在人类皮肤、相关癌症和人类皮肤衍生细胞培养物中的表达。

• DOI: 10.1016/j.toxlet.2014.09.028
• 发表时间: 2015
• 期刊: Toxicology letters
• 影响因子: 3.5
• 作者: Slusser,Andrea;Zheng,Yun;Zhou,XuDong;Somji,Seema;Sens,DonaldA;Sens,MaryAnn;Garrett,ScottH
• 通讯作者: Garrett,ScottH

Brain changes associated with thromboxane receptor antagonist SQ 29,548 treatment in a mouse model.

小鼠模型中与血栓素受体拮抗剂 SQ 29,548 治疗相关的大脑变化。

• DOI: 10.1002/jnr.23578
• 发表时间: 2015
• 期刊: Journal of neuroscience research
• 影响因子: 4.2
• 作者: Rebel,AndrewA;Urquhart,SiriA;Puig,KendraL;Ghatak,Atreyi;Brose,StephenA;Golovko,MikhailY;Combs,ColinK
• 通讯作者: Combs,ColinK

AMBYSTOMA MAVORTIUM (Barred Tiger Salamander). BEHAVIOR UNDERNEATH THE ICE.

AMBYSTOMA MAVORTIUM（横纹虎蝾螈）。

• 发表时间: 2013
• 期刊: Herpetological review
• 作者: Radi,Alexander;Beachy,ChristopherK
• 通讯作者: Beachy,ChristopherK