Nano Material Initiative

纳米材料倡议

• 批准号: 8544370
• 负责人: STEVEN GRAVES
• 金额: $ 23.96万
• 依托单位: BATTELLE MEMORIAL INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2015-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8544370
• 关键词: Adverse effects; Biological; Blood; Chemicals; Contracts; Development; Dose; Ensure; Environmental Exposure; Evaluation; Exposure to; Goals; Hazard Identification; Hazardous Chemicals; Health; Heightened Cancer Risk; Human; Nanotechnology; National Toxicology Program; Outcome; Risk Assessment; Risk Factors; Sampling; Specific qualifier value; Testing; Toxic effect; Toxicity Tests; Work; animal tissue; disorder prevention; fullerene C60; method development; nano; nanomaterials; public health research; sound

The National Toxicology Program (NTP) is developing a broad-based research program to address potential human health hazards associated with the manufacture and use of nanomaterials. This initiative is driven by the intense current and anticipated future research and development focus on nanotechnology. The goal of these studies is to provide sufficient dose response information on a defined set of nanomaterials with characterized lengths and diameters to allow the development of quantitative hazard assessments for inhalation exposures of these materials. It was proposed to develop a broad based research project to evaluate the comparative inhalation toxicity after subchronic and chronic exposure of different nano materials. In support of NTPs goal following various chemistry tests are performed on different test articles (multiwalled carbon nanotubes, fullerene C60, titanium dioxide). The tasks includes, bulk material procurement and analysis, method development & chemical analysis, dose formulation development, biological sample method development & analysis, etc.

国家毒理学计划（NTP）正在制定一项基础广泛的研究计划，以解决与纳米材料的制造和使用相关的潜在人类健康危害。这项倡议是由当前和预期的未来纳米技术研究和发展的强烈关注推动的。这些研究的目的是提供一组具有特征长度和直径的纳米材料的充分剂量反应信息，以便对这些材料的吸入暴露进行定量危害评估。建议开展一个基础广泛的研究项目来评估比较