Breast Oncology

乳腺肿瘤学

• 批准号: 8388296
• 负责人: FRANK PATRICK MCCORMICK
• 金额: $ 0.01万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-05 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8388296
• 关键词: Area; Basic Science; Bioinformatics; Biological; Biology; Breast; Budgets; California; Cancer Center Support Grant; Clinical Research; Clinical Trials; Communities; Companions; Diagnostic; Discipline; Disease; Early Diagnosis; Environment; Epidemiology; Etiology; Funding; Genetic; Goals; Grant; Health; Individual; Intervention; Joints; Laboratories; Malignant Neoplasms; Methods; Modeling; Morbidity - disease rate; Outcome; Patients; Peer Review; Physicians; Population Research; Publications; Radiation Oncology; Research; Research Infrastructure; Research Personnel; Risk; Science; Series; Site; System; Testing; Therapy Clinical Trials; Translations; Universities; Work; base; cancer prevention; care delivery; clinical care; improved; innovation; malignant breast neoplasm; meetings; member; mortality; multidisciplinary; new therapeutic target; novel; oncology; oncology program; outreach; programs; tumor; tumor progression

The Breast Oncology Program (Program) is comprised of 39 Program Members from 13 different UCSF departments. The Program supports and stimulates basic, clinical, and population research in breast cancer and facilitates the translation of these findings into improved cancer management and control. The Program's themes are as follows: (1) epidemiology and etiology; (2) cancer prevention, risk models, and early detection; (3) genetics and biology of cancer progression; (4) new therapeutic targets and approaches; and (5) outreach, clinical care delivery, and outcomes. Research in the Program is supported by the Bay Area Breast Cancer SPORE, eight large multi-disciplinary, multi-institutional projects that support work in one or more themes, a multi-campus University of California Office of the President sponsored ATHENA Breast Health Network integrating clinical care and research by numerous individual investigator-initiated grants. Since the last competitive renewal much effort has been dedicated towards investigator initiated therapeutic trials, innovative companion diagnostic clinical trials, testing new radiation oncology treatment delivery systems including correlative science, as well as establishing a CLIA-compliant testing laboratory and an integrative bioinformatics and IT infrastructure. The Program has become more cohesive, has a high level of interaction that has led to new grant funding with joint program and project leaders and co-investigators across disciplines. Interactions between Program members are encouraged in several discussion forums, including a weekly multidisciplinary seminar, an annual retreat, a weekly tumor board, a bi-weekly breast site study review meeting, a monthly community forum, and a patient-physician management discussion series. The Program has $22,189,900 total peer-reviewed support for the last budget year. The Program has 17% intra-programmatic and 17% inter-programmatic publications.

乳腺肿瘤学项目（项目）由来自 UCSF 13 个不同科室的 39 名项目成员组成。该计划支持和促进乳腺癌的基础、临床和人群研究，并促进将这些研究结果转化为改进的癌症管理和控制。该计划的主题如下：（1）流行病学和病因学； (2) 癌症预防、风险模型和早期发现； (3) 癌症进展的遗传学和生物学； (4)新的治疗靶点和方法； (5) 外展、临床护理服务和结果。该计划的研究得到湾区乳腺癌 SPORE 的支持，这是八个大型多学科、多机构项目，支持一个或多个主题的工作，加州大学总统办公室赞助的多校区雅典娜乳腺健康网络整合了临床护理和由众多个人​​研究者发起的资助的研究。 自上次竞争性更新以来，我们一直致力于研究者发起的治疗试验、创新的伴随诊断临床试验、测试新的放射肿瘤治疗交付系统（包括相关科学），以及建立符合 CLIA 标准的测试实验室以及综合生物信息学和 IT 基础设施。该计划变得更有凝聚力，具有高水平的互动，从而为联合计划和项目领导者以及跨学科的联合研究人员提供了新的赠款资金。鼓励计划成员在多个讨论论坛上进行互动，包括每周一次的多学科研讨会、年度静修会、每周一次的肿瘤委员会、每两周一次的乳腺部位研究审查会议、每月一次的社区论坛以及患者-医生管理讨论系列。该计划在上一个预算年度获得的同行评审支持总额为 22,189,900 美元。该计划有 17% 的计划内出版物和 17% 的计划间出版物。