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RARC- RESEARCH ANIMAL RESOURCE CENTER

RARC-研究动物资源中心

基本信息

批准号：
8375220
负责人：
NEIL SCOTT LIPMAN
金额：
$ 136.82万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至 2013-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8375220
关键词：
Accreditation Analgesics Anatomy Anesthesia procedures Anesthetic Gases Anesthetics Animal Euthanasia Animal Experimentation Animal Model Animal Sources Animal Welfare Act Animals Applied Research Area Autopsy Basic Science Beds Biocompatible Materials Biological Body Fluids Cancer Center Support Grant Canis familiaris Caring Clinical Comparative Pathology Consultations Containment Decontamination Development Diagnosis Diagnostic Procedure Diagnostics Research Diet Disease Education Effectiveness Ensure Environment Equipment Evaluation Exclusion Exercise Fluoroscope Genetically Engineered Mouse Glass Hazardous Chemicals Health Health Services Health Status Housing Human IACUC Image Immunocompromised Host Individual Infectious Agent International Investigation Isoflurane Laboratories Laboratory Animal Medicine Laboratory Animals Laboratory Research Maintenance Malignant Neoplasms Medical center Memorial Sloan-Kettering Cancer Center Methods Microscope Modality Monitor Mycoplasma Neoplasms New York Operating Rooms Operative Surgical Procedures Oral Oryctolagus cuniculus Parasites Pathology Pharmacy facility Phenotype Physiology Play Policies Postoperative Period Preparation Procedures Process Quality Control Quarantine Radioisotopes Recovery Room Regulation Research Research Activity Research Personnel Research Support Resources Rodent Role Safety Sampling Science Sentinel Serologic tests Services Slice Source Sterilization Surgeon Surveys System Techniques Tissues Toxic effect Training United States National Institutes of Health United States Public Health Service Universities Vaporizer Vendor Veterinarians Virus Water Writing Xenograft procedure animal care animal facility animal model development animal resource arm cancer therapy clinical care computerized digital feeding feral guide for the care and use of laboratory animals imaging modality improved in vivo instrument medical schools microbial nonhuman primate nutrition operation pathogen programs quality assurance square foot treatment planning tumor wasting

项目摘要

The Research Animal Resource Center (RARC) supports animal model development and use at MSKCC. At MSKCC, animal models are used in basic and applied investigational studies. Animals are employed in diverse areas including the development of new methods for diagnosis and treatment of cancer, and the elucidation of the basic biological mechanisms resulting in neoplasia. RARC is comprised of six sections: 1.) Husbandry and Operations; 2.) Animal Health Service (AHS); 3.) Education and Quality Assurance (EQA); 4.) Laboratory of Comparative Pathology (LCP); 5.) Genetically Engineered Mouse Phenotyping (GEM) Core; and, 6.) Administration and Finance, which provide housing for and humane care to over 90,000 animals daily utilized by 99 research laboratories. RARC's oversight of MSKCC's AAALACaccredited, centrally managed, animal care and use program ensures the efficient use of available space and staff resources and allows for close professional monitoring of the in vivo (animal) research program. RARC operates three specialized state-of-the-art facilities encompassing over 66,000 net square feet of space which provide critical environments and the specialized equipment necessary for the maintenance and use of a variety of animal models. RARC's board-certified professional and paraprofessional staff (83 FTE) serve as a consultative and technical resource for MSKCC investigators on all matters related to animal research, The AHS's veterinary and veterinary technical staff ensure that all animals' receive appropriate clinical care and ensure that MSKCC's rodent colonies remain pathogen free by routinely surveying colony health and quarantining all incoming rodents from atypical vendors. Additionally, AHS staff perform technical procedures for research staff in support of their animal research programs. The LCP and the GEM core provide clinical and anatomic pathology services which ensure the health of the resident colonies but are also used extensively in support of individual laboratory's research programs. RARC's extensive educational program is administered by the EQA section which provides training to research staff via didactic and hands-on sessions as well as various written instructional materials. RARC also provides post-graduate training to veterinarians in both Laboratory Animal Medicine and Science, and Comparative Pathology in conjunction with the Weil Medical College of Cornell University, the Rockefeller University, and the Animal Medical Center.

研究动物资源中心（RARC）支持MSKCC动物模型的开发和使用。