Tri-Institutional Training Program in Laboratory Animal Medicine and Science

实验动物医学和科学三机构培训计划

• 批准号: 8272075
• 负责人: NEIL SCOTT LIPMAN
• 金额: $ 9.02万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8272075
• 关键词: American; Americas; Anatomy; Animals; Area; Award; Basic Science; Biomedical Research; Censuses; Clinical; Clinical Management; Clinical Pathology; Clinical Research; Comparative Pathology; Core Facility; Discipline; Educational Curriculum; Ensure; Environment; Faculty; Funding; Gene Targeting; Government; Health; Home environment; Human; Institution; Journals; Laboratories; Laboratory Animal Medicine; Laboratory Animal Science; Laboratory Animals; Length; Memorial Sloan-Kettering Cancer Center; Mentors; Methods; Pathologist; Personal Satisfaction; Pharmacologic Substance; Process; Regulatory Affairs; Research; Research Activity; Research Project Grants; Research Support; Research Training; Resources; Rotation; Schools; Science; Series; Services; Social Welfare; Specialist; Structure; Time; Training; Training Programs; United States; United States National Academy of Sciences; United States National Institutes of Health; Universities; Veterinarians; Veterinary Medicine; animal resource; bioimaging; biomedical scientist; biosecurity; clinical care; college; comparative; experience; medical schools; medical specialties; member; monoclonal antibody production; operation; programs; symposium

DESCRIPTION (provided by applicant): The Memorial Sloan-Kettering Cancer Center, The Rockefeller University, and the Weill Cornell Medical College are seeking federal funding to support three trainees in their Tri-Institutional Training Program in Laboratory Animal Medicine and Science (TTP-LAMS). The training program structure and the research environment and facilities utilized for training are unique and unparalleled. Trainees are mentored by highly experienced TTP-LAMS program faculty including board-certified laboratory animal veterinarians (6) and comparative pathologists (3), as well as specialists in biomedical imaging, vivarium operations and administration, regulatory affairs, monoclonal antibody production, and gene-targeting. Trainees are exposed to world-class faculty conducting biomedical research in diverse scientific disciplines. The tri-institutional faculty is among the most distinguished medicl and biomedical scientists in the world. The three institutions are the home for more than 37 members of the National Academy of Sciences and 8 Nobel laureates receiving more than 900 NIH awards totalling ~$ 300 M annually. Training is conducted within 14 state-of-the-art tri- institutional vivaria in which an average daily census of greater than 300,000 animals representing 14 species is maintained. The multi-disciplinary Laboratory of Comparative Pathology, providing anatomic and clinical pathology services, and various research core facilities are at the disposal of the trainee. The 3-year TTP- LAMS program is divided into two principal components: experiential and didactic. The experiential component is divided into two principal areas: Clinical, Management, and Administrative Training (CMAT) and independent Research Training. CMAT introduces trainees to all aspects of academic animal resource program management and operations as well as the clinical care and research utilization of laboratory animal species. There are nine CMAT rotations of varying lengths completed during 93 weeks. Research training (63 weeks) provides trainees the opportunity to apply the scientific method to a basic or clinical research project and to develop an appreciation for the process of scientific discovery. Didactic training includes the completion of graduate level courses offered by the Weill Cornell Graduate School of Medical Sciences, attending various program sessions including weekly a clinical and pathology conference and a laboratory animal medicine and science seminar series (providing ~ 230 h total contact time), as well as biweekly biosecurity case conferences and journal club. PUBLIC HEALTH RELEVANCE: Laboratory animals are vital to basic and translational biomedical research activities in the United States. The discoveries made utilizing laboratory animals in numerous scientific disciplines have resulted in countless and far-reaching improvements to human as well as animal health and welfare. Laboratory animal veterinarians serve as stewards for this critical resource providing the necessary expertise to ensure the animals' health and well-being. Training in laboratory animal medicine is cursory, at best, in America's colleges and schools of veterinary medicine. Veterinarians seeking expertise in this discipline generally complete post- graduate specialty training at an academic, government or pharmaceutical biomedical research center in which laboratory animals are used in support of the research enterprise. This award will allow the tri-institutional consortium, consisting of the Memorial Sloan-Kettering Cancer Center, The Rockefeller University, and the Weill Cornell Medical College to provide post- graduate specialty training in laboratory animal medicine to three veterinarians.

描述（由申请人提供）：纪念斯隆-凯特琳癌症中心、洛克菲勒大学和威尔康奈尔医学院正在寻求联邦资助，以支持他们的实验动物医学和科学三机构培训计划（TTP-LAMS）的三名学员。培训项目结构、研究环境和培训设施都是独一无二的。学员由经验丰富的TTP-LAMS项目教师指导，包括委员会认证的实验动物兽医和比较病理学家，以及生物医学成像、动物手术和管理、监管事务、单克隆抗体生产和基因靶向方面的专家。学员将接触到世界一流的教师，在不同的科学学科中进行生物医学研究。这三所大学的教员是世界上最杰出的医学和生物医学科学家之一。这三个机构是超过37名美国国家科学院成员和8名诺贝尔奖获得者的家园，他们每年获得900多个NIH奖项，总额约为3亿美元。训练是在14个最先进的三机构舍内进行的，其中平均每天有超过30万只动物，代表14个物种。提供解剖学和临床病理学服务的多学科比较病理学实验室以及各种研究核心设施可供学员使用。为期3年的TTP- LAMS项目分为两个主要部分：体验式和教学式。经验部分分为两个主要领域：临床，管理和行政培训（CMAT）和独立研究培训。CMAT向学员介绍学术动物资源项目管理和运作的各个方面，以及实验动物物种的临床护理和研究利用。在93周内完成了9个不同长度的CMAT轮转。研究培训（63周）为受训者提供了将科学方法应用于基础或临床研究项目的机会，并培养了对科学发现过程的欣赏。教学培训包括完成威尔康奈尔医学科学研究生院提供的研究生课程，参加各种项目会议，包括每周一次临床和病理学会议和实验动物医学和科学系列研讨会（提供约230小时的总接触时间），以及每两周的生物安全案例会议和期刊俱乐部。