CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8365042
• 负责人: ROBERT S SHERWIN
• 金额: $ 41.71万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365042
• 关键词: Acquired Immunodeficiency Syndrome; Award; Clinical Sciences; Research; Research Infrastructure; Translational Research; Universities; programs

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. DESCRIPTION (provided by applicant): The Yale Center for Clinical Investigation (YCCI) was created to provide a "home" for training the next generation of clinical investigators. Key programmatic goals are to 1) attract highly talented students and junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering; and train them in the use of state-of-the-art research tools; give them the skills to work within complex research teams; and support their professional development; and 2) foster the translation of disease-related discoveries from the laboratory into the clinic and then the community by: stimulating the creation of interdisciplinary teams; making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources; establishing organizational and regulatory infrastructure for clinical studies; and forging new partnerships that will integrate community leaders, physicians, and health centers and encourage participation in research. Participating institutions include the Schools of Medicine, Nursing, and Public Health, the department of Biomedical Engineering and the Graduate Programs in Biological and Biomedical Sciences. The Junior Faculty Scholars award program and the Investigative Medicine program (IMP) are central to YCCI's education and training efforts. IMP is a unique doctoral program that offers Ph.D. degrees in Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical research and the junior faculty scholars program is a career development program. YCCI has also created a Society of Mentors who participates actively in the training and nurturing of the YCCI Scholars. Pilot and feasibility (P&F) grants will be awarded for: 1) interdisciplinary translational team research; 2) development of novel methodologies; 3) Use of Core (incl imaging) technologies; and 4) community-based research. YCCI will cluster research cores around common themes, including: imaging; genomics and proteomics; cell and tissue based tech; Integrated metabolics; cognition and biobehavior; and animal models. The Office of Research Services will provide robust facilities and resources for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have an office to coordinate the University's efforts to address health issues facing our community and our national community. PUBLIC HEALTH RELEVANCE (provided by applicant): This research has direct relevance to public health in that its goals are to facilitate clinical research, including by training the next generation of clinical researchers that will lead to better treatments for human disease and better health outcomes.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 描述（由申请人提供）：耶鲁临床研究中心 (YCCI) 的创建是为了提供培训下一代临床研究人员的“家”。主要计划目标是：1）吸引医学、护理、公共卫生、生物科学和生物医学工程领域的高素质学生和初级教师；并培训他们使用最先进的研究工具；赋予他们在复杂的研究团队中工作的技能；并支持他们的职业发展； 2) 通过以下方式促进与疾病相关的发现从实验室转化为临床，然后转化为社区： 刺激跨学科团队的创建；提供最先进的核心设施和扩大的生物统计和生物信息学资源；建立临床研究的组织和监管基础设施；建立新的伙伴关系，将社区领袖、医生和卫生中心结合起来，并鼓励参与研究。参与机构包括医学院、护理学院和公共卫生学院、生物医学工程系以及生物和生物医学科学研究生项目。青年教师学者奖励计划和研究医学计划（IMP）是 YCCI 教育和培训工作的核心。 IMP 是一个独特的博士项目，提供博士学位。为从事转化或临床研究职业的高素质医学博士研究员提供健康科学研究学位，而初级教师学者计划是一项职业发展计划。 YCCI还成立了导师协会，积极参与YCCI学者的培训和培养。试点和可行性 (P&F) 资助将授予： 1) 跨学科转化团队研究； 2）开发新方法； 3) 核心（包括成像）技术的使用； 4) 以社区为基础的研究。 YCCI 将围绕共同主题聚集研究核心，包括：成像；基因组学和蛋白质组学；基于细胞和组织的技术；综合代谢；认知和生物行为；和动物模型。研究服务办公室将为监管、生物统计、生物信息学、招聘和其他支持服务提供强大的设施和资源。 YCCI 将设立一个办公室来协调大学的工作，解决我们社区和国家社区面临的健康问题。 公共健康相关性（由申请人提供）：这项研究与公共健康直接相关，因为其目标是促进临床研究，包括培训下一代临床研究人员，从而为人类疾病提供更好的治疗方法和更好的健康结果。