YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAM

耶鲁大学临床与转化科学奖励计划

• 批准号: 8365039
• 负责人: ROBERT S SHERWIN
• 金额: $ 260.82万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365039
• 关键词: Award; Clinical Sciences; Translational Research; Universities; programs

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. DESCRIPTION (provided by applicant): The Yale Center for Clinical Investigation (YCCI) was created to provide a "home" for training the next generation of clinical investigators. Key programmatic goals are to 1) attract highly talented students and junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering; and train them in the use of state-of-the-art research tools; give them the skills to work within complex research teams; and support their professional development; and 2) foster the translation of disease-related discoveries from the laboratory into the clinic and then the community by: stimulating the creation of interdisciplinary teams; making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources; establishing organizational and regulatory infrastructure for clinical studies; and forging new partnerships that will integrate community leaders, physicians, and health centers and encourage participation in research. Participating institutions include the Schools of Medicine, Nursing, and Public Health, the department of Biomedical Engineering and the Graduate Programs in Biological and Biomedical Sciences. The Junior Faculty Scholars award program and the Investigative Medicine program (IMP) are central to YCCI's education and training efforts. IMP is a unique doctoral program that offers Ph.D. degrees in Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical research and the junior faculty scholars program is a career development program. YCCI has also created a Society of Mentors who participates actively in the training and nurturing of the YCCI Scholars. Pilot and feasibility (P&F) grants will be awarded for: 1) interdisciplinary translational team research; 2) development of novel methodologies; 3) Use of Core (incl imaging) technologies; and 4) community-based research. YCCI will cluster research cores around common themes, including: imaging; genomics and proteomics; cell and tissue based tech; Integrated metabolics; cognition and biobehavior; and animal models. The Office of Research Services will provide robust facilities and resources for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have an office to coordinate the University's efforts to address health issues facing our community and our national community. PUBLIC HEALTH RELEVANCE (provided by applicant): This research has direct relevance to public health in that its goals are to facilitate clinical research, including by training the next generation of clinical researchers that will lead to better treatments for human disease and better health outcomes.

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 描述（由申请人提供）：耶鲁大学临床研究中心（YCCI）的创建是为了为培训下一代临床研究者提供一个“家”。主要计划目标是1）吸引医学，护理，公共卫生，生物科学和生物医学工程领域的优秀学生和初级教师;并培训他们使用最先进的研究工具;让他们掌握在复杂的研究团队中工作的技能;并支持他们的专业发展;（2）通过鼓励跨学科团队的创建，促进将与疾病相关的发现从实验室转化为临床，然后转化为社区;提供最先进的核心设施和扩大的生物统计和生物信息学资源;建立临床研究的组织和监管基础设施;建立新的伙伴关系，将社区领导人，医生和健康中心整合在一起，并鼓励参与研究。参与机构包括医学，护理和公共卫生学院，生物医学工程系和生物和生物医学科学研究生课程。青年教师学者奖计划和调查医学计划（IMP）是YCCI教育和培训工作的核心。IMP是一个独特的博士课程，提供博士学位。从健康科学研究到高质量医学博士研究员从事翻译或临床研究的职业生涯和初级教师学者计划是一个职业发展计划。YCCI还创建了一个导师协会，他们积极参与YCCI学者的培训和培养。试点和可行性（P&F）赠款将授予：1）跨学科翻译团队研究; 2）开发新方法; 3）使用核心（包括成像）技术;和4）基于社区的研究。YCCI将围绕共同主题聚集研究核心，包括：成像;基因组学和蛋白质组学;基于细胞和组织的技术;综合代谢;认知和生物行为;和动物模型。研究服务办公室将为监管、生物统计、生物信息学、招聘和其他支持服务提供强大的设施和资源。YCCI将有一个办公室来协调大学的努力，以解决我们的社区和我们的国家社区面临的健康问题。 公共卫生相关性（由申请人提供）：本研究与公共卫生直接相关，因为其目标是促进临床研究，包括培训下一代临床研究人员，从而为人类疾病提供更好的治疗方法和更好的健康结果。