CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

CTSA 儿科研究基础设施

• 批准号: 8365041
• 负责人: ROBERT S SHERWIN
• 金额: $ 237.11万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365041
• 关键词: Award; Clinical Sciences; Pediatric Research; Research Infrastructure; Translational Research; Universities; programs

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. DESCRIPTION (provided by applicant): The Yale Center for Clinical Investigation (YCCI) was created to provide a "home" for training the next generation of clinical investigators. Key programmatic goals are to 1) attract highly talented students and junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering; and train them in the use of state-of-the-art research tools; give them the skills to work within complex research teams; and support their professional development; and 2) foster the translation of disease-related discoveries from the laboratory into the clinic and then the community by: stimulating the creation of interdisciplinary teams; making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources; establishing organizational and regulatory infrastructure for clinical studies; and forging new partnerships that will integrate community leaders, physicians, and health centers and encourage participation in research. Participating institutions include the Schools of Medicine, Nursing, and Public Health, the department of Biomedical Engineering and the Graduate Programs in Biological and Biomedical Sciences. The Junior Faculty Scholars award program and the Investigative Medicine program (IMP) are central to YCCI's education and training efforts. IMP is a unique doctoral program that offers Ph.D. degrees in Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical research and the junior faculty scholars program is a career development program. YCCI has also created a Society of Mentors who participates actively in the training and nurturing of the YCCI Scholars. Pilot and feasibility (P&F) grants will be awarded for: 1) interdisciplinary translational team research; 2) development of novel methodologies; 3) Use of Core (incl imaging) technologies; and 4) community-based research. YCCI will cluster research cores around common themes, including: imaging; genomics and proteomics; cell and tissue based tech; Integrated metabolics; cognition and biobehavior; and animal models. The Office of Research Services will provide robust facilities and resources for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have an office to coordinate the University's efforts to address health issues facing our community and our national community. PUBLIC HEALTH RELEVANCE (provided by applicant): This research has direct relevance to public health in that its goals are to facilitate clinical research, including by training the next generation of clinical researchers that will lead to better treatments for human disease and better health outcomes.

该子项目代表CTSA资金百分比的估计值 被用于广泛的研究领域（艾滋病研究，儿科研究或 临床试验）。 列出的总成本只是CTSA数量的估计值 基础设施朝向这一研究领域，而不是直接提供的资金 NCRR授予subproject或subproject人员。 描述（由申请人提供）：创建了耶鲁大学临床调查中心（YCCI），以提供一个“家”，用于培训下一代临床研究者。关键的程序化目标是1）吸引跨医学，护理，公共卫生，生物科学和生物医学工程的高度才华的学生和初级教师；并培训他们使用最先进的研究工具；给他们在复杂的研究团队中工作的技能；并支持他们的专业发展； 2）通过以下方式促进了从实验室转化为诊所，然后促进社区的转化：刺激跨学科团队的创建；提供最先进的核心设施，并扩大生物统计学和生物信息学资源；建立临床研究的组织和监管基础设施；并建立新的伙伴关系，以整合社区领导者，医师和卫生中心并鼓励参与研究。参与的机构包括医学，护理和公共卫生，生物医学工程系以及生物学和生物医学科学的研究生计划。初级学者奖和调查医学计划（IMP）是YCCI的教育和培训工作的核心。 IMP是提供博士学位的独特博士课程。卫生科学研究学士学位是高素质的医学博士研究员，从事转化或临床研究的职业和初级教师学者计划是一项职业发展计划。 YCCI还建立了一个导师会，他们积极参与YCCI学者的培训和培养。飞行员和可行性（P＆F）赠款将获得：1）跨学科翻译团队研究； 2）开发新方法； 3）使用核心（包括成像）技术； 4）基于社区的研究。 YCCI将研究核心研究核心，包括：成像；基因组学和蛋白质组学；基于细胞和组织的技术；综合代谢；认知和生物行为；和动物模型。研究服务办公室将为监管，生物统计，生物信息学，招聘和其他支持服务提供强大的设施和资源。 YCCI将设有一个办公室来协调大学为解决我们社区和国家社区面临的健康问题所做的努力。 公共卫生相关性（由申请人提供）：这项研究与公共卫生的直接相关，因为其目标是促进临床研究，包括培训下一代临床研究人员，这将为人类疾病和更好的健康结果提供更好的治疗。