The 2nd Biennial Science of Global Prostate Cancer Disparities in Black Men of Af

描述(申请人提供)：尽管前列腺癌(CAP)在美国总人口中的发病率近年来有所下降，但黑人男性的前列腺癌死亡率是白人男性的两到三倍。到目前为止，人们对美国黑人男性与高加索男性之间的CAP发病率差异还知之甚少。令人进一步关切的是，关于加勒比、联合王国和西非其他黑人男子戴帽子负担的文献越来越多。尽管黑人男性可能共享一个共同的基因风险基因，导致CAP的发病率较高，但在生活在不同环境和文化中的黑人男性中观察到的风险变异性的病因学突出了对可能改变这些生物风险因素的行为因素的贡献的强烈和不断发展的认识。我们和其他人的初步观察表明，使用共同的方法和统一的工具研究黑人男性CAP的行为、环境和遗传决定因素对我们来说很重要。因此，CAP科学家、临床医生和倡导者之间的全球合作对于理解CAP病因学和开发有效解决CAP差异的干预措施非常重要。2010年，第一届两年一度的“全球黑人前列腺癌差异科学”会议于2010年8月27-29日在佛罗里达州杰克逊维尔举行。在国家癌症研究所(R13 CA144439)的支持下，首届会议取得了压倒性的成功。为了继续发展和维护我们的全球实践社区，本次会议赠款申请的目标是 将CAP科学家、临床医生、幸存者和倡导者聚集在一起，分享贯穿CAP的研究问题，并制定下一步的研究重点，以实现全球前列腺健康公平。第二届两年一度的会议将于2012年11月1日至4日在巴哈马举行。2012年会议的主题是“前列腺癌的全球负担：经济、临床和人文结果”。 与公共卫生相关：第二届“全球黑人前列腺癌差异的科学”双年度会议被提议将CAP科学家、临床医生、幸存者和倡导者聚集在一起，分享贯穿CAP的研究问题，并制定下一步的研究重点，以实现全球前列腺健康公平。

DESCRIPTION (provided by applicant): Although the prostate cancer (CaP) incidence rates in the overall US population has declined in recent years, mortality from CaP is two to three times greater among Black men compared to White men. To date the disparate incidence of CaP in Black men in the US compared to their Caucasian counterparts is poorly understood. Of further concern is the growing literature on the burden of CaP among other Black men in the Caribbean, the United Kingdom and West Africa. Although Black men may share a common genetic risk locus contributing to the higher incidence of CaP, the etiology of the variability in risk observed among Black men living in varying environments and cultures highlights the strong and evolving knowledge of the contribution of behavioral factors that may modify these biological risk factors. Our preliminary observations and that of others point to the fact that it s important for us to study the behavioral, environmental and genetic determinants of CaP among Black men using common methodologies and uniform instruments. Global collaborations among CaP scientists, clinicians and advocates are thus important to understand CaP etiology and develop interventions that will effectively address CaP disparities. In 2010, the 1st biennial conference on "The Science of Global Prostate Cancer Disparities in Black Men" was held in Jacksonville Florida, August 27 -29, 2010. Supported by the National Cancer Institute (R13 CA144439), the first conference was an overwhelming success. To continue to develop and maintain our global community of practice, the objective of this conference grant application is to bring CaP scientists, clinicians, survivors, and advocates together to share cross cutting CaP research issues and develop the next research priorities to achieve prostate health equity globally. The 2nd biennial conference will be held in The Bahamas from Nov 1 - 4, 2012. The theme for the 2012 conference is "The Global Burden of Prostate Cancer: Economic, Clinical and Humanistic Outcomes". PUBLIC HEALTH RELEVANCE: The 2nd Biennial conference on "The Science of Global Prostate Cancer Disparities in Black Men" is proposed to bring CaP scientists, clinicians, survivors, and advocates together to share cross cutting CaP research issues and develop the next research priorities to achieve prostate health equity globally.