Administrative Core

项目摘要（参见说明）： 拉什艾滋病毒和老龄化差异卓越中心 (Rush CEDHA) 的总体目标是提供基础设施来支持协作、多学科流行病学研究，重点是了解和消除艾滋病毒老龄化相关后果中的种族差异。行政核心将对 Rush CEDHA 进行全面的科学领导，以设定中心的总体方向，确保 Rush CEDHA 资源的最佳利用，并作为国家和地方层面健康差异相关活动的资源。全面科学的责任 领导权将由担任 CEDHA 主任的 Barnes 博士承担，并与执行委员会共同行使领导权，该执行委员会由两名副主任、核心领导、统计学家和数据经理、一名管理员以及代表 Rush CEDHA 资源用户的 CEDHA 外部成员组成。其他三个委员会将履行具体职能，以帮助拟议的中心实现其目标。内部顾问委员会由来自三个合作机构的六名代表组成 - 拉什大学、库克县小约翰·H·斯特罗格医院（露丝·M·罗斯坦核心中心）和伊利诺伊大学芝加哥分校将就 Rush CEDHA 的工作方向和 sen/e 提供建议，作为就重大决策达成共识的机制。外部咨询委员会由来自机构外部、在健康差异、艾滋病毒或老龄化研究方面在全国享有盛誉的杰出成员组成，将评估 Rush CEDHA 的进展，并就 CEDHA 的努力方向提供建议。临床数据和生物样本分配委员会将评估所有 请求数据、接触研究参与者以及在研究核心中评估的人员的生物样本。最后，管理员将管理中心的财务，以确保中心资源的有效利用。

PROJECT SUMMARY (See instructions): The overall goal of the Rush Center of Excellence on Disparities in HIV and Aging (Rush CEDHA) is to provide an infrastructure to support collaborative, multidisciplinary epidemiologic research focused on understanding and eliminating racial disparities in the aging-related consequences of HIV. The Administrative Core will exercise overall scientific leadership of the Rush CEDHA in order to set the overall direction of the Center, ensure optimal utilization of Rush CEDHA resources, and serve as a resource for health disparities related activities at the national and local level. The responsibility for overall scientific leadership will rest with Dr. Barnes as CEDHA Director and is shared with and exercised through the Executive Committee composed of the two Associate Directors, the Core Leaders, the statistician and data manager, and an administrator, and members outside the CEDHA representing users ofthe Rush CEDHA resources. Three other committees will carry out specific functions to aid the proposed Center in achieving its goals. The Internal Advisory Board, composed of six representatives from the three partnering institutions - Rush University, John H. Stroger, Jr. Hospital of Cook County (Ruth M. Rothstein CORE Center), and University of Illinois at Chicago, will provide advice concerning the directions of Rush CEDHA efforts and sen/e as a mechanism for reaching consensus on major decisions. The External Advisory Board, composed of distinguished members from outside the institution with national prominence in research on health disparities, HIV, or aging will assess Rush CEDHA progress and provide advice concerning the direction CEDHA efforts should take. The Clinical Data and Biospecimen Distribution Committee will evaluate all requests for data, access to participants for research studies, and biospecimens from persons evaluated in the Research Core. Finally, the Administrator will manage Center finances to ensure the efficient use of Center resources.