MRI catheter design and fabrication
MRI catheter design and fabrication
批准号:
8344989
负责人:
Robert J Lederman
金额:
$80.79万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AnatomyArteriesBypassCathetersChronicClinicalDevelopmentDevicesFrequenciesGoalsHeart DiseasesHeatingImaging DeviceImaging TechniquesImplantLocationMagnetic Resonance ImagingMechanicsMitral Valve InsufficiencyNational Heart, Lung, and Blood InstituteNeedlesPatientsPeripheralPolymersProceduresPropertyProtocols documentationRadioSafetyShunt DeviceSolutionsSystemTestingTimeTransjugular intrahepatic portosystemic shunt procedureVentricular Septal DefectsWorkbasedesignimprovednitinolnovelrepairedsafety testingtool
中文摘要
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英文摘要
During the past year we have continued our work developing magnetic resonance imaging (MRI) compatible and visible devices to perform endoluminal interventional procedures that are planned to perform under MRI. We have developed first MRI compatible guidewire that provides both tip and shaft visibility under MRI at the same time. We have also developed the first polymer catheter shaft that can be visualized during the procedure without effecting its mechanical properties.
We are developing clinical-grade catheter and compatible guidewire system to perform simple endoluminal interventional procedures in peripheral arteries to recanalize chronic total occlusion of peripheral arteries.
We are developing MRI compatible and visible active needle to perform Transjugular Intrahepatic Portosystemic Shunt (TIPS) procedure under MRI. We are also improving our catheter-based solution to treat functional mitral valve regurgitation. We are beginning development of clinical grade tools using MRI compatible materials to perform these investigational procedures in patients.
We continue to develop nitinol based implants like extra anatomic bypass shunt and resonant staple. We also continue to develop deflectable active guiding catheter that is required to deliver these implants to target anatomical location.
We continue to work on radio frequency heating safety tests of interventional MRI devices. We currently work on to develop a new general protocole to test heating safety of active intravascular devices during real time MRI procedures.
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Diagnostic and interventional cardiovascular catheterization
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批准号:8940179
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项目类别:
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资助金额:$120.51万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Real-time MRI guided cardiovascular intervention
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批准号:8939792
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项目类别:
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资助金额:$144.51万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Biological and mechanical therapies enabled by cardiovascular interventional MRI
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批准号:7594421
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项目类别:
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资助金额:$315.56万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
MRI and X-ray catheter design and prototyping
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批准号:10929117
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项目类别:
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资助金额:$92.17万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Diagnostic and interventional cardiovascular catheterization
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批准号:9353171
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项目类别:
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资助金额:$103.61万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Biological and mechanical therapies enabled by cardiovas
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批准号:7321629
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Biological and mechanical therapies enabled by cardiovas
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批准号:6822883
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Real-time MRI guided cardiovascular intervention
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批准号:8557942
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项目类别:
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资助金额:$121.14万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Real-time cardiovascular MRI and co-registration technical development
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批准号:8557994
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项目类别:
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资助金额:$80.76万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
MRI catheter design and fabrication
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批准号:8746879
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项目类别:
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资助金额:$79.84万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Novel catheter treatment of valve disease
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批准号:8939827
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项目类别:
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资助金额:$28.92万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
MRI cardiovascular catheterization applications
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批准号:10685872
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项目类别:
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资助金额:$125.58万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Biological and mechanical therapies enabled by cardiovascular interventional MRI
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批准号:7735004
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项目类别:
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资助金额:$284.43万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
MRI cardiovascular catheterization technology development
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批准号:10929115
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项目类别:
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资助金额:$61.45万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
MRI and X-ray catheter design and prototyping
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批准号:10003774
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项目类别:
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资助金额:$97.96万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Diagnostic and interventional cardiovascular catheterization
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批准号:10003804
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项目类别:
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资助金额:$129.54万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
MRI cardiovascular catheterization technology development
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批准号:10003772
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项目类别:
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资助金额:$66.38万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
MRI and X-ray catheter design and prototyping
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批准号:10253833
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项目类别:
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资助金额:$99.52万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Real-time cardiovascular MRI and co-registration technical development
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批准号:8149559
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项目类别:
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资助金额:$80.42万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
Gene transfer for Duchenne Muscular Dystrophy
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批准号:8158036
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项目类别:
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资助金额:$60.31万
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财政年份:--
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负责人:Robert J Lederman
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依托单位:
海外基金