IMPROVING AUTOMATION AND KINETICS CAPABILITIES AT BIOCAT

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Automation is essential for increasing the thoughput of the BioCAT SAXS beamline. We proposed to implement automated SAXS measurements in both equilibrium and kinetic modes at BioCAT. Test applications were on protein folding. We integrated the control of syringe pumps with shutters and data acquisition.