COMPARATIVE PROTEOMICS AND GLYCOPROTEOMICS OF PROTEINS SECRETED FROM B CINEREA

灰霉病菌分泌蛋白质的比较蛋白质组学和糖蛋白质组学

基本信息

  • 批准号:
    8363013
  • 负责人:
  • 金额:
    $ 6.02万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2011
  • 资助国家:
    美国
  • 起止时间:
    2011-06-01 至 2012-05-31
  • 项目状态:
    已结题

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The fungus Botrytis cinerea is a widespread plant pathogen that affects many vegetables and fruits, as well as a large number of shrubs, trees, flowers, and weeds by causing grey mold or soft rot on the host tissues. B. cinerea mainly infects dicotyledons and non-graminaceous monocotyledons, and the infection not only occurs during the growth phase of crops but also during storage of the harvested products. Thus, it is responsible for significant economic losses. A great deal of research has focused on understanding the B. cinerea infection process, which in turn directs the development of effective prevention strategies. B. cinerea must breach the cell wall during the infection process and accordingly secretes a great number of enzymes that can degrade cell walls. Little is known concerning the identity of these enzymes. The majority of these cell wall degrading enzymes are glycosylated. Although the glycosylation on several recombinant proteins have been characterized, very little is known on the native enzymes, despite the importance of glycosylation on protein structure and activity. To this end, we have started to characterize the secreted proteome and glycoproteome of this fungus.
这个子项目是利用这些资源的众多研究子项目之一

项目成果

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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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RON ORLANDO其他文献

RON ORLANDO的其他文献

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{{ truncateString('RON ORLANDO', 18)}}的其他基金

Isotopically Labeled Heparan Sulfate Glycosaminoglycan Disaccharides for use as Internal Standards
用作内标的同位素标记硫酸乙酰肝素糖胺聚糖二糖
  • 批准号:
    10080563
  • 财政年份:
    2020
  • 资助金额:
    $ 6.02万
  • 项目类别:
CREATING ANTIBODIES TO ENABLE THE STUDY OF MYCOBACTERIUM TUBERCULOSIS INFECTIONS IN GUINEA PIGS
创造抗体以研究豚鼠结核分枝杆菌感染
  • 批准号:
    10027950
  • 财政年份:
    2019
  • 资助金额:
    $ 6.02万
  • 项目类别:
Generation of antibodies to monitor Notch O-fucosylation in vivo
生成用于监测体内 Notch O-岩藻糖基化的抗体
  • 批准号:
    9200115
  • 财政年份:
    2016
  • 资助金额:
    $ 6.02万
  • 项目类别:
Development of Isotopically Labeled Glycoproteins for use as Internal Standards
开发用作内标的同位素标记糖蛋白
  • 批准号:
    9908593
  • 财政年份:
    2015
  • 资助金额:
    $ 6.02万
  • 项目类别:
Development of Isotopically Labeled Glycoproteins for use as Internal Standards
开发用作内标的同位素标记糖蛋白
  • 批准号:
    8834650
  • 财政年份:
    2015
  • 资助金额:
    $ 6.02万
  • 项目类别:
Site-specific O-GlcNAc MAbs: New Tools for Glycoproteomics
位点特异性 O-GlcNAc MAb:糖蛋白组学的新工具
  • 批准号:
    8395145
  • 财政年份:
    2012
  • 资助金额:
    $ 6.02万
  • 项目类别:
Site-specific O-GlcNAc MAbs: New Tools for Glycoproteomics
位点特异性 O-GlcNAc MAb:糖蛋白组学的新工具
  • 批准号:
    8546432
  • 财政年份:
    2012
  • 资助金额:
    $ 6.02万
  • 项目类别:
GLYCOPROTEIN GLYCOMICS: EXPRESSION IN MOUSE ES CELLS & PROGENY
糖蛋白糖组学:小鼠 ES 细胞中的表达
  • 批准号:
    8363005
  • 财政年份:
    2011
  • 资助金额:
    $ 6.02万
  • 项目类别:
DEVELOPMENT OF TECHNIQUES FOR QUANTITATIVE GLYCOMICS
定量糖组学技术的发展
  • 批准号:
    8363021
  • 财政年份:
    2011
  • 资助金额:
    $ 6.02万
  • 项目类别:
PORCINE REPRODUCTIVE & RESPIRATORY SYNDROME VIRUS-ASSOCIATED GLYCANS
猪繁殖
  • 批准号:
    8363119
  • 财政年份:
    2011
  • 资助金额:
    $ 6.02万
  • 项目类别:

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