JOINT ANALYSIS OF ESR LINESHAPES AND PROTON NMR DISPERSION PROFILES

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 Acert在运动动力学研究中的一个长期目标是将从线形的多频ESR研究中获得的互补弛豫信息与核磁共振自旋弛豫相结合，特别是与频率相关的核磁共振弥散方法NMRD。该项目由波兰和瑞典的研究小组组成，是对过渡金属离子络合物溶液的ESR和NMRD的联合研究。为了更好地了解Gd(III)络合物的性质，并验证常用的瞬时零场分裂(ZFS)赝旋模型的适用性，对Gd(III)络合物作为磁共振造影剂进行了初步研究。根据该模型，瞬时零位移场由定义在其自身主轴系统中的恒定幅度张量来描述，该张量根据各向同性扩散方程改变其相对于实验室坐标系的方向，该各向同性扩散方程具有反映扭曲运动的时间尺度的特征时间常数(相关时间)。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. A long-term objective of ACERT in the study of motional dynamics has been to combine the complementary relaxation information obtained from multi-frequency ESR studies of lineshapes and NMR spin-relaxation, in particular the frequency-dependent NMR Dispersion method NMRD. This project, with groups in Poland and Sweden, is to a combined study on ESR and NMRD on solutions of transition metal ion complexes. Initial work is on Gd(III) complexes used as contrast agents in MRI in order to better understand their properties, and to verify the applicability of the commonly used pseudorotational model of transient zero field splitting (ZFS). According to this model the transient ZFS is described by a tensor of a constant amplitude, defined in its own principal axes systems, which changes its orientation with respect to the laboratory frame according to an isotropic diffusion equation with a characteristic time constant (correlation time) reflecting the time scale of the distortional motion.