IDENTIFICATION OF HUMAN PROTEINS IN A MOUSE XENOGRAPH MODEL

小鼠异种模型中人类蛋白质的鉴定

• 批准号: 8365848
• 负责人: Christine Wu Nordahl
• 金额: $ 0.65万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365848
• 关键词: A Mouse; Biology; Collaborations; Fatty acid glycerol esters; Funding; Fungal Genome; Genes; Grant; Harvest; Human; Human Genome; Human Identifications; Modeling; Mus; National Center for Research Resources; Plasma; Principal Investigator; Proteins; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; cost; tumor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Identification of proteins that are secreted from a tumor into plasma is a daunting analytical challenge. In collaboration with the Lewis lab, human tumors were placed into the fat pad of mice. Plasma was harvested from mice and we hope to analyze the plasma to identify proteins that originate from genes encoded by the human genome.

这个子项目是利用这些资源的众多研究子项目之一