Characterization and Treatment of Sensory Intolerance in Childhood

儿童期感觉不耐受的特征和治疗

• 批准号: 8308123
• 负责人: Christine A Conelea
• 金额: $ 5.14万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8308123
• 关键词: Address; Adult; Anxiety; Attention deficit hyperactivity disorder; Auditory; Autistic Disorder; Behavioral; Categories; Characteristics; Child; Childhood; Chronic; Clinic; Clinical; Data; Development; Developmental Therapeutics Program; Diagnosis; Diagnostic; Dimensions; Disease; Distress; Emotional; Epidemiology; Esthesia; Family Leave; Funding; Future; Gilles de la Tourette syndrome; Goals; Grant; High Prevalence; Impairment; Intervention; Life; Maintenance; Manuscripts; Medicaid; Mental disorders; Mentorship; National Institute of Child Health and Human Development; National Research Service Awards; Obsessive-Compulsive Disorder; Preparation; Prevalence; Primary Health Care; Psychopathology; Recruitment Activity; Research; Research Personnel; Research Technics; Research Training; Sampling; School-Age Population; Sensory; Staging; Stimulus; Structure; Symptoms; Tactile; Testing; Time; Training; Writing; base; career; cost; design; experience; functional disability; novel; psychologic; research and development; response; sensory integration; sensory stimulus; skills; social; statistics; theories; therapy development

DESCRIPTION (provided by applicant): This F32 National Research Service Award is designed to help the PI achieve her long-term career goal of becoming an independent investigator with lines of research focused on understanding the phenomenology and treatment of obsessive-compulsive spectrum disorders. Consistent with this goal, the proposed study will focus on extending the PI's research to the characterization and treatment of sensory intolerance (SI) in childhood. SI is an exaggerated, intense, and/or prolonged behavioral response toward certain sensations, such as tactile or auditory input. SI is a chronic condition associated with significant distress and functional impairment that may set the stage for the development of psychopathology later in life. Despite the high prevalence rate of SI, there are large gaps in the understanding of SI phenomenology and treatment that could be addressed by psychiatric research. Although SI is thought to cut across current diagnostic categories, little is known about the relationship of SI to other psychiatric disorders and symptom dimensions, information that is critical for future treatment development. In addition, there is a lack of available empirically- based treatment for SI. Thus, the overall aims of the current study are to 1) recruit 46 children from primary care clinics with SI complaints and conduct a comprehensive, clinician-administered assessment to better characterize and define SI and 2) pilot-test an exposure-based treatment in six children with primary SI symptoms using a multiple baseline design. The long term goal of the proposed study is designed to generate preliminary data necessary to begin a line of research focused on a) understanding the phenomenology, development, and maintenance of SI and b) developing an empirically supported intervention for SI. The highly structured training plan in the current application is ideally suited to allow the I to conduct the proposed research plan and to move towards her long-term career goals. The PI will receive training in 1) assessment, characterization, and clinical presentation of SI, 2) treatment development research techniques, 3) exposure-based therapy, 4) advanced statistics, and 5) manuscript preparation and grant writing skills. Training will be guided by an expert mentorship team with expertise in SI, exposure therapy, developmental psychopathology, and treatment development. Therefore, the proposed training and research plans will provide the PI with experiences necessary to accomplish her ultimate goal of becoming an independent investigator. PUBLIC HEALTH RELEVANCE: Sensory Intolerance (SI) is a chronic condition associated with significant distress and impairment that may set the stage for the development of psychopathology later in life. Despite the high prevalence rate of SI, there are large gaps in the understanding of SI characteristics and treatment that could be addressed by psychiatric research. The current study proposes to examine the relationship of SI to other psychiatric disorders and to pilot-test a novel psychological treatment for SI.

描述（由申请人提供）：该F32国家研究服务奖旨在帮助PI实现她的长期职业目标，即成为一名独立研究者，研究人员专注于了解强迫症的现象学和治疗。与这个目标一致，拟议的研究将集中于将PI的研究扩展到儿童期感官不耐受（SI）的表征和治疗。 SI是对某些感觉（例如触觉或听觉输入）的夸张，强烈和/或延长行为反应。 SI是一种与严重困扰和功能障碍相关的慢性病，​​可能为以后的生活中的心理病理学奠定了基础。尽管SI的患病率很高，但对SI现象学和治疗的理解仍有很大的差距，可以通过精神病研究来解决。尽管认为SI跨越了当前的诊断类别，但很少 知道SI与其他精神疾病和症状维度的关系，这对于未来的治疗发展至关重要。此外，缺乏针对SI的可用基于经验的治疗方法。因此，当前研究的总体目的是1）招募46名来自SI投诉的初级保健诊所的儿童，并进行全面的，临床医生的管理评估，以更好地表征和定义SI和2）在六个使用多个基线设计的初级SI症状的儿童中，基于暴露的治疗方法。拟议的研究的长期目标旨在生成必要的初步数据，以开始一系列研究，重点是a）了解SI和B）了解SI的现象学，开发和维护。 当前申请中高度结构化的培训计划非常适合允许I执行拟议的研究计划并朝着她的长期职业目标迈进。 PI将接受1）评估，表征和临床表现的培训，2）治疗开发研究技术，3）基于暴露的治疗，4）高级统计和5）手稿准备和赠款写作技巧。培训将由具有SI，曝光疗法，发育心理病理学和治疗发展的专业知识的专业知识的专业指导团队指导。因此，拟议的培训和研究计划将为PI提供必要的经验，以实现成为独立研究者的最终目标。 公共卫生相关性：感官不宽容（SI）是一种与严重困扰和障碍相关的慢性病，​​可能为后期的心理病理学发展奠定了基础。尽管SI的患病率很高，但对SI特征和治疗的理解仍有很大的差距，可以通过精神病研究来解决。当前的研究建议检查SI与其他精神疾病的关系，并试用SI的新型心理治疗。