Research Training for Medical Geneticists at Mount Sinai School of Medicine

描述：这是一项名为“西奈山医学院医学遗传学家研究培训计划”的培训补助金的新申请。该项目的总体目标是培养一批医学遗传学家，使其成为医学遗传学研究的学术领袖。研究培训的重点将是基因组学、蛋白质组学、药物遗传学、复杂特征、单基因疾病以及基于分子的疗法的开发方面的转化研究。该计划内的所有内科科学家将得到至少两年的支持，以提供足够的时间让他们获得有意义的基础科学实验室经验，我们计划每年招募三名实习生。该方案将建立在大量资源的基础上，包括：1)对内科科学家的培训作出强有力的机构承诺；2)生物科学研究生院在#年提供广泛的教育。 基础科学、转化医学和以患者为导向的研究；2)在西奈山存在了几十年的医学遗传学及其所有子专业的强大和全面的培训计划；3)在遗传学、基因组学和蛋白质组学方面存在资金充足的多学科研究计划；以及4)研究所的广泛的转换研究基础设施。西奈山医学遗传学研究金计划的具体目标是：1)针对每个受训者的具体需要，提供研究生水平的教学培训；2)指导研究培训，为研究员提供竞争研究资金所需的技能；以及3)在拨款撰写、职业建设和获得研究资金方面的实践指导，以及研究伦理方面的指导。除了正式的教学课程外，所有研究员都将参加每两周一次的遗传学和基因组学研究系列活动，以及每年一次的遗传学和基因组学研究日，每个日都是为本培训计划专门创建的，以提供专门的课程，供学员和教职员工互动，并促进 这群人的凝聚力。已经制定了详细的方案评估计划、对研究员进行负责任的研究的培训以及招聘代表人数不足的少数族裔候选人的计划。该计划将由一个执行学院委员会和一个外部咨询委员会提供建议。

DESCRIPTION: This is a new application for a training grant entitled "Research Training Program for Medical Geneticists at the Mount Sinai School of Medicine." The overall goal of the program is to prepare a cadre of medical geneticists to become academic leaders in medical genetics research. The emphasis of the research training will be on translational research in genomics, proteomics, pharmacogenetics, complex traits, single gene disorders, and the development of molecular-based therapies. All physician scientists within this program will be supported for a period of at least two years to provide sufficient time for them to attain a meaningful basic science laboratory experience, and we plan to recruit three trainees per year. The program will build upon considerable resources including: 1) a strong institutional commitment to the training of physician scientists; 2) extensive educational offerings of the Graduate School of Biological Sciences in basic science, translational medicine and patient oriented research; 2) robust and comprehensive training programs in medical genetics and all its subspecialties that have existed at Mount Sinai for decades, 3) the existence of well funded, multidisciplinary research programs in genetics, genomics, and proteomics; and 4) extensive translational research infrastructure of the institution. The specific objectives of the Mount Sinai Fellowship Program in Medical Genetics are to provide: 1) graduate-level didactic training specific to the needs of each individual trainee; 2) mentored research training that will provide the fellows with the skills necessary to compete for research funding; and 3) practical instruction in grant writing, career building and obtaining research funding, and instruction in the ethical conduct of research. In addition to formal didactic courses, all fellows will participate in a bi-weekly Genetics and Genomics Research series and an annual Genetics and Genomics Research Day each of which have been specifically created for this training program to provide dedicated sessions for interaction among trainees and faculty and to promote cohesiveness of this group of fellows. Detailed plans for program evaluation, training of fellows in the responsible conduct of research and a plan for the recruitment of underrepresented minority candidates have been formulated. The program will be advised by an Executive Faculty Committee and an External Advisory Board.