Bioinformatics and Computational Biology Training Program

描述(由申请人提供)：本提案是杜克大学计算生物学和生物信息学(CBB)项目培训补助金申请的重新提交。CBB是一个研究生项目。它招收自己的学生，并授予博士学位。它的使命是培养下一代科学家，他们将在生命科学和定量科学之间工作。CBB在头两年为学生提供支持，之后他们将转向教职员工的支持。该项目的目标是每年招收大约10名新生。这项提案需要10个名额，这将支持一半的学生。该项目通常需要五年时间来完成，它包含了广泛的学术活动，包括三门核心课程和三次研究轮换，都是在第一年进行的，一系列必修研讨会，仔细的RCR培训，以及跨学科的指导和监督。该项目得到了一个异常广泛但融合良好的教职员工群体的支持。该学院的研究领域相当广泛，分为六个领域：系统生物学、基因组分析、计算结构生物学、基因组医学、进化基因组学和生物系统数学与统计模型。学生们准备好在合作研究小组中工作，在那里，生物学家和计算科学家为解决真正的生物学问题做出共同的智力贡献。CBB即将完成其从NIH获得的初始资金的第五个年头。在这五年里，杜克大学的计算生物学取得了显著的增长，该项目目前包括来自三所学校和一个研究所的15个系的57名教员(量化系24人，生物系33人)。该项目录取了优秀的学生，自项目开始以来录取的49名学生中，有43名完成了博士学位或在攻读学位方面取得了很好的进步，保留率非常高。毕业生表现非常出色，其中6人在著名机构担任博士后职位，4人在工业领域占据重要职位。

DESCRIPTION (provided by applicant): This proposal is a resubmission of an application for a training grant for the Duke University Program in Computational Biology and Bioinformatics (CBB). CBB is a graduate program. It admits its own students and grants the PhD. Its mission is to educate the next generation of scientists who will work at the interface between the life sciences and the quantitative sciences. CBB supports students for their first two years, after which they move onto support from the faculty. The program aims to admit around ten new students each year. This proposal requests ten slots, which would support half the students. The program typically takes five years to complete, and it embodies a wide range of academic activities, including three core courses and three research rotations, all taken in the first year, a required seminar series, careful RCR training, and interdisciplinary mentoring and supervision. The program is supported by an unusually broad, but well integrated group of faculty. Research areas of the faculty are quite broad, and are grouped into six areas: Systems Biology, Genome Analysis, Computational Structural Biology, Genomic Medicine, Evolutionary Genomics and Mathematical and Statistical Modeling of Biological Systems. Students emerge well prepared to work in collaborative research groups where biologists and computational scientists make joint intellectual contributions to solving real biological problems. CBB is completing its fifth year of initial funding from the NIH. These five years have seen significant growth of computational biology at Duke University, the program now includes 57 faculty (24 in quantitative departments and 33 in biological ones) from 15 departments in three schools and one Institute. Excellent students have bee recruited into the Program and retention is excellent with 43 of the 49 students that have been admitted since the program began having finished their PhD or making good progress towards their degree. Graduates have done extremely well, 6 have taken postdoctoral positions at prestigious institutions and 4 have taken strong industrial positions.