Advances in Plasmodium Vivax Malaria Research

间日疟原虫疟疾研究进展

• 批准号: 8529293
• 负责人: JANE M CARLTON
• 金额: $ 0.6万
• 依托单位: NEW YORK ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-10 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8529293
• 关键词: Academia; Academy; Accounting; Address; Age; Asia; Asian Americans; Award; Awareness; Biology; Cessation of life; Child; Child Care; Clinical; Clinical Research; Clinical Trials; Collaborations; Communication; Communities; Congresses; Consensus; Country; Data; Development; Diagnosis; Disabled Persons; Disease; Doctor of Philosophy; Drug Industry; Drug resistance; Electronics; Ensure; Europe; Fellowship; Fostering; Foundations; Future; Generations; Genetic; Genomics; Goals; Government; Health Policy; In Vitro; Individual; Infection; International; Knowledge; Latin America; Life; Literature; Malaria; Mentors; Minority; Minority Groups; Mission; Molecular Biology; Molecular Genetics; Multimedia; Museums; National Institute of Child Health and Human Development; New York; Online Systems; Oral; Parasites; Participant; Plasmodium vivax; Prevention; Prevention Research; Prevention strategy; Printing; Process; Public Health; Publications; Reporting; Research; Research Personnel; Research Technics; Science; Severities; Spain; Technical Expertise; Technology; Translations; Travel; United States; Vivax Malaria; Woman; abstracting; career; data exchange; design; disability; drug discovery; economic impact; improved; in vivo; international center; lectures; meetings; neglect; novel; posters; prevent; public health relevance; symposium

DESCRIPTION (provided by applicant): Plasmodium vivax is the most widely distributed malaria parasite. There has been growing evidence that P. vivax is responsible for a significant proportion of global disease, and half of all malaria cases in Latin America and Asia. Despite recent recognition that the overall burden, economic impact, and severity of P. vivax disease have been underestimated, this species remains underrepresented in the scientific literature and fora. To address this unmet need, the New York Academy of Sciences, "la Caxia" Foundation, and International Center for Scientific Debate will jointly present a 2.5-day scientifi conference, Advances in Plasmodium Vivax Malaria Research, to be held at the CosmoCaixa science museum in Barcelona, Spain on June 5-7, 2013. The main objectives of the conference are to: (i) Provide a neutral forum for exchange of novel scientific knowledge and expertise among P. vivax investigators; (ii) Foster collaborations between complementary research groups and implementation teams, to enhance and leverage knowledge and technical expertise, and to prevent experimental redundancy; (iii) Showcase early career and underrepresented investigators (i.e. women, ethnic/racial minorities, and persons with disabilities) in P. vivax research via short talks, poster sessions, travel fellowships, and career mentoring; (iv) Disseminate the conference proceedings; and (v) Foster partnerships among academia, clinicians, government and regulatory agencies, to promote the global imperative of malaria control and eradication through the discussion and design of existing and future strategies. The conference is anticipated to attract approximately 150 international attendees from the United States and Europe, as well as Latin American and Asian countries in which P. vivax is endemic. Sessions will explore P. vivax molecular biology and genomics, host-parasite interactions, novel research techniques ('omics) to overcome barriers to in vitro, in vivo, and clinical study of P. vivax; drug resistance and drug discovery; and recent clinical trial and in-field efforts in P. vivx prevention, treatment, and control. Thematically, the conference goals align well with the NIAID's mission to find effective means by which to control and ultimately eliminate malaria. The majority of life-threatening P. vivax infections occur in children under the age of five years, consistent with the imperative of the NICHD to ensure the ability of children to live healthy, productive, disease-free lives. Lectures, interactive discussions, networking breaks, and a conference reception will provide a neutral forum for interaction of an international community who may not otherwise regularly interact at a single scientific meeting, ensuring that recent advances in P. vivax biology and public health strategies are disseminated among those at the forefront of vivax research. The dissemination of knowledge originating from the conference via an open-access, online multimedia report and additional print publication will ultimately foster advancement in the diagnosis, prevention, and treatment of this neglected parasite.

描述（申请人提供）：间日疟原虫是分布最广泛的疟疾寄生虫。越来越多的证据表明，间日疟原虫是全球很大一部分疾病的罪魁祸首，占拉丁美洲和亚洲所有疟疾病例的一半。尽管最近认识到间日疟原虫疾病的总体负担、经济影响和严重程度被低估，但该物种在科学文献和论坛中的代表性仍然不足。为了解决这一未满足的需求，纽约科学院、“la Caxia”基金会和国际科学辩论中心将于2013年6月5日至7日在西班牙巴塞罗那的CosmoCaixa科学博物馆联合举办一次为期2.5天的科学会议，题为“间日疟原虫疟疾研究进展”。会议的主要目标是：(i)为间日疟研究人员之间交流新的科学知识和专门知识提供一个中立的论坛；（ii）促进互补性研究小组和实施小组之间的合作，加强和利用知识和技术专长，并防止实验冗余；（三）通过简短谈话、海报会议、旅行奖学金和职业指导，展示间日疟研究的早期职业和代表性不足的调查人员（即妇女、少数民族/种族和残疾人）；散发会议记录；（五）促进学术界、临床医生、政府和管理机构之间的伙伴关系，通过讨论和设计现有和未来战略，促进控制和消灭疟疾的全球必要性。这次会议预计将吸引来自美国和欧洲以及间日疟流行的拉丁美洲和亚洲国家的大约150名国际与会者。会议将探讨间日疟原虫分子生物学和基因组学、宿主-寄生虫相互作用、新的研究技术（组学），以克服间日疟原虫体外、体内和临床研究的障碍；耐药性和药物发现；以及最近在间日疟原虫预防、治疗和控制方面的临床试验和现场工作。从主题上讲，会议的目标与NIAID寻找控制并最终消除疟疾的有效手段的使命非常一致。危及生命的间日疟原虫感染大多数发生在五岁以下儿童中，这符合联合国儿童健康与发展中心确保儿童能够过上健康、有生产力和无疾病生活的要求。讲座、互动讨论、联谊休息和会议招待会将为国际社会的互动提供一个中立的论坛，否则他们可能不会定期在一次科学会议上互动，确保在间日疟原虫生物学和公共卫生战略方面的最新进展在间日疟原虫研究的前沿人员中传播。通过开放获取的在线多媒体报告和额外的印刷出版物传播来自会议的知识，最终将促进对这种被忽视的寄生虫的诊断、预防和治疗方面的进展。