Structurally Diverse Encoded Peptide Sets

结构多样化的编码肽组

• 批准号: 8515689
• 负责人: Igor A. Kozlov
• 金额: $ 34.19万
• 依托单位: PROGNOSYS BIOSCIENCES, INC.
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8515689
• 关键词: Amino Acids; Amino Acyl Transfer RNA; Amino Acyl-tRNA Synthetases; Biological Assay; Chemistry; Codon Nucleotides; Custom; DNA; Development; Diagnosis; Diagnostic; Diagnostic Imaging; Disease; Drug Delivery Systems; Drug Targeting; Elements; Evaluation; Gelatinase A; Gelatinase B; Generations; Goals; Government; Imaging Device; In Vitro; Indium; Individual; Length; Libraries; Ligands; MMP14 gene; Matrix Metalloproteinases; Medical; Methods; Modeling; Molecular Biology; Nucleic Acids; Oligonucleotides; Peptide Hydrolases; Peptide Library; Peptide Synthesis; Peptides; Performance; Persons; Pharmaceutical Preparations; Phase; Production; Proteomics; Protocols documentation; RNA, Transfer, Amino Acid-Specific; Reagent; Research; Services; Specificity; System; Techniques; Technology; Therapeutic; Translating; Translations; Work; base; cDNA Library; cost; cost effective; design; drug development; improved; inhibitor/antagonist; member; new technology; novel diagnostics; programs; public health relevance; screening; tool

DESCRIPTION: There is a need for new proteomics technologies to enable production and screening of large structurally diverse peptide sets. We propose to develop a novel technology for synthesis and assaying of highly multiplexed sets of encoded peptides at low cost.

描述：需要新的蛋白质组学技术来生产和筛选结构多样的大肽组。我们建议开发一种新的技术，用于以低成本合成和测定高度多路复用的编码肽。