Mutant Mouse Regional Resource Center Annual Meeting.

突变小鼠区域资源中心年会。

• 批准号: 8546461
• 负责人: TERRY R MAGNUSON
• 金额: $ 1.72万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-18 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8546461
• 关键词: Address; Advisory Committees; Archives; Atlases; Beta Cell; Biological Preservation; Biomedical Research; California; Cellular biology; Collection; Communication; Communities; Country; Defect; Development; Disease susceptibility; ES Cell Line; Electronic Mail; Ensure; Equipment and supply inventories; Funding; Gene Expression; Genes; Genetic; Genetic Models; Genetically Engineered Mouse; Genomics; Goals; Growth; Health; Human; Human Resources; Individual; Informatics; Institution; Life; Link; Medicine; Metric; MicroRNAs; Missouri; Modeling; Monitor; Mouse Strains; Mus; Mutagenesis; Mutant Strains Mice; National Center for Research Resources; Nature; Nervous system structure; Neurosciences; North Carolina; Pathway interactions; Performance; Persons; Pharmacologic Substance; Pigmentation physiologic function; Policies; Principal Investigator; Production; Request for Proposals; Research; Research Infrastructure; Research Personnel; Research Support; Resource Sharing; Resources; Services; Strategic Planning; Subgroup; Technology; Teleconferences; The Jackson Laboratory; Time; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; comparative; cost; human disease; improved; meetings; member; model development; mouse model; mutant; mutant mouse model; operation; organizational structure; programs; promoter; repository; success; symposium; tool

DESCRIPTION (provided by applicant): The Mutant Mouse Regional Resource Centers (MMRRC) were created in 1999 to meet the increasing demand for a centralized resource for archiving and distributing genetically modified mouse strains to the research community. The Centers are part of a multi-institutional, nationally distributed resource program with four repositories located strategically in the Western (University of California-Davis), Central (University of Missouri), and Eastern (University of North Carolina-Chapel Hill and The Jackson Laboratory) USA, and a single, centralized Informatics, Coordination and Service Center (ICSC at University of California- Davis) that provides a single interface to the scientific user community. The common goal is to provide mouse model resources and research support services to the research community. In addition, the centers use their expertise to research and implement new related technologies. As the production of genetically engineered mice has increased dramatically, the centers have expanded to include an inventory of over 32,527 mutant and genetically engineered mouse strains maintained as live colonies, cryopreserved germplasm, and embryonic stem (ES) cell lines and have filled ~4,080 orders from ~3550 investigators at over 2000 institutions worldwide. In a nationally distributed, multi-institutional program with a common goal, there is a critical need for high level of coordinated communication. Day-to day operations, management and development of short term strategies are discussed by email as well as in monthly teleconferences between key personnel at all of the Centers and NIH program staff and periodic teleconferences for subgroups addressing specific Center needs. However, there is no real substitute for regular in-person meetings; therefore, this proposal requests funding for the MMRRC to organize and plan annual meetings over the coming five year period. Such annual meetings are critical to 1) provide sufficient time and face-to-face interactions to review progress and discuss short- and long-term planning strategies to ensure that the MMRRC Program continues to evolve to serve the rapidly evolving needs of the scientific community and 2) provides a venue for showcasing the MMRRC program to NIH officers and other relevant members of the scientific community and inviting their input.

描述（由申请人提供）：突变小鼠区域资源中心 (MMRRC) 成立于 1999 年，旨在满足研究界对集中资源存档和分发转基因小鼠品系日益增长的需求。这些中心是多机构、全国性分布的资源计划的一部分，四个存储库战略性地分布在美国西部（加州大学戴维斯分校）、中部（密苏里大学）和东部（北卡罗来纳大学教堂山分校和杰克逊实验室），以及一个单一的集中信息学、协调和服务中心（加州大学戴维斯分校的 ICSC），为科学用户社区提供单一界面。共同目标是为研究界提供小鼠模型资源和研究支持服务。此外，这些中心还利用其专业知识来研究和实施新的相关技术。随着基因工程小鼠产量的急剧增加，这些中心已扩大到包括超过 32,527 个突变体和基因工程小鼠品系的库存，这些小鼠品系以活菌落、冷冻种质和胚胎干 (ES) 细胞系的形式保存，并已满足全球 2000 多个机构的约 3550 名研究人员的约 4,080 个订单。在全国分布的、多机构的 具有共同目标的计划，迫切需要高水平的协调沟通。日常运营、管理和短期战略的制定通过电子邮件以及所有中心关键人员和 NIH 项目工作人员之间的每月电话会议以及满足特定中心需求的小组定期电话会议进行讨论。然而，定期的面对面会议并没有真正的替代品。因此，该提案要求为 MMRRC 提供资金，以便在未来五年内组织和规划年度会议。此类年会对于以下方面至关重要：1) 提供充足的时间和面对面的互动，以审查进展情况并讨论短期和长期规划策略，以确保 MMRRC 计划继续发展，以满足科学界快速变化的需求；2) 提供一个向 NIH 官员和科学界其他相关成员展示 MMRRC 计划并邀请他们提出意见的场所。