Duke CTSA (Composite)

杜克 CTSA（复合）

• 批准号: 8721512
• 负责人: ROBERT M CALIFF
• 金额: $ 541.66万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-26 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8721512
• 关键词: Biometry; Clinical Research; Clinical Trials; Communities; Development; Discipline; Disease; Education; Electronic Health Record; Ensure; Environment; Ethics; Fostering; Funding; Goals; Health Sciences; Health Services; Health system; Home environment; Human; Information Technology; Instruction; Learning; Link; Mentors; Outcome; Patients; Process; Productivity; Registries; Research; Research Infrastructure; Research Personnel; Resources; Safety; Schools; Science; Site; System; Training; Training Programs; Translational Research; Translations; Update; Vision; base; bench to bedside; biobank; cost; cost effectiveness; implementation science; improved; innovation; medical specialties; multi-site trial; new technology; next generation; population based; systems research; tool

To fulfill tlie new NCATS vision for the CTSA Consortium and accelerate scientific discoveries into improved outcomes for patients, academic health and science systems must invest, transform, and innovate to optimize their unique strengths. Our vision, aligned with that of NCATS, is to create a research environment at Duke that stimulates the translation of scientific discovery from bench to bedside by 1) linking discovery science to a creative engine that efficiently accelerates development of new technologies; and 2) integrating clinical trials, registries, and electronic health records in a learning health system where research and practice form a continuum. Our research environment will be driven by scientific merit and societal need, "agnostic" to disease or specialty discipline, aligned with our updated institutional framework for research oversight and quality, and continually evaluated for academic productivity, efficiency, and cost. To achieve these goals, we will create an Integrated Home for clinical and translational research by providing infrastructure and resources to serve investigators and trainees across the research spectrum. We will offer resources based upon common needs among our researchers, including education, biostatistics, biobanking, regulatory expertise, ethics, pilot funding and recruitment assistance. We will also tailor our offerings to specialized needs across research communities that include early translation, proof of concept, site-based research and population based research, which includes multi-site trials, outcomes, health services, implementation science and community engaged research. Integrating these resources will require a new tool, a portal for all trainees and investigators, MyResearchHome@Duke, and its human counterpart, MyResearchTeam@Duke. These tools will provide a single point of entry for all clinical and translational research at Duke, regardless of their department or school. Thus, we will enhance our Integrated Home for clinical and translational research with a combination of sophisticated information technology and mentoring and navigation; provide access to common and specialized resources for all of our translational research communities and train the next generation of researchers in our educational and training programs. RELEVANCE (See instructions): The CTSA will foster the translational research process, ensuring that new discoveries are developed and evaluated more quickly and that clinical research is done with high quality, efficiency, safety and cost- effectiveness.

实现 CTSA 联盟的新 NCATS 愿景并加速科学发现以改进 患者的结果、学术健康和科学系统必须投资、转型和创新 优化他们的独特优势。我们的愿景与 NCATS 一致，是创造一个研究环境 杜克大学通过以下方式促进科学发现从实验室到临床的转化：1）将发现联系起来 科学成为有效加速新技术开发的创新引擎； 2）整合 学习健康系统中的临床试验、登记和电子健康记录，其中研究和 实践形成一个连续体。我们的研究环境将由科学价值和社会需求驱动， 对疾病或专业学科“不可知”，与我们更新的研究机构框架保持一致 监督和质量，并不断评估学术生产力、效率和成本。达到 为了实现这些目标，我们将通过提供以下服务来创建临床和转化研究的综合之家： 为整个研究领域的研究人员和受训人员提供服务的基础设施和资源。我们将提供 基于我们研究人员共同需求的资源，包括教育、生物统计学、生物样本库、 监管专业知识、道德、试点资金和招聘援助。我们还将定制我们的产品 研究社区的特殊需求，包括早期翻译、概念验证、基于站点的 研究和基于人群的研究，包括多地点试验、结果、卫生服务、 实施科学和社区参与的研究。整合这些资源需要新的 工具，所有学员和研究人员的门户网站，MyResearchHome@Duke 及其人类对应物， 我的研究团队@杜克大学。这些工具将为所有临床和转化提供单一入口点 在杜克大学进行研究，无论其院系或学校如何。因此，我们将加强我们的综合家居 结合先进信息技术和指导的临床和转化研究 和导航；为我们所有的转化研究提供通用和专业资源的访问 社区并在我们的教育和培训计划中培训下一代研究人员。 相关性（参见说明）： CTSA 将促进转化研究进程，确保新发现的开发和应用 评估速度更快，临床研究高质量、高效、安全、低成本地完成 效力。