The Use of LC/MS, GC/MS, ICP/MS and ELISA Techniques for the screening and identi

项目概要/摘要 该提案的目的是继续我们实验室参与 蕨帽。这将使我们能够继续对食品和食品进行分析 发生化学食品污染事件时的产品 可能危及我国食品供应的安全。我们将会 根据需要参与所设计方法的开发和扩展 筛选各种食品基质中的各种潜在有害化学物质， 使用 GC/MS、LC/MS、ICP/MS 和 ELISA 分析包括未知化合物 方法论。实验室人员将参加培训演练 旨在评估 FERN 应对各种污染的能力 情景，参加国家和地区培训会议，并协助 现有 FERN 方法的验证和扩展。实验室将 参与对我们现有质量保证/质量控制的评估 制定计划并解决所发现的任何缺陷。我们的质量计划将是 通过我们参加 FERN 熟练程度练习进行测试。 具体而言，将要实现的目标包括： ¿ 对实验室人员进行 FERN 分析方法培训 ¿ 参与国家和地区 FERN 培训机会 ¿ 提供分析专业知识以改进、扩展和 现有 FERN 方法的验证 ¿ 根据需要协助开发新的 FERN 方法 出现 ¿ 参加 FERN 能力测试项目 ¿ 现有 FERN 设备的维护 ¿ 与其他 FERN 实验室合作，确保有效性 FERN计划 ¿ 根据需要参与响应或监视演习 ¿ 通过使用与其他 FERN 实验室进行有效沟通 电子信息网

Project Summary/Abstract The objective of this proposal is to continue our laboratory's involvement in the FERN CAP. This will enable us to continue with the analyses of foods and food products in the event that there is a chemical food contamination incident that potentially compromises the safety of our nation's food supply. We will be participating, as needed, in the development and expansion of methods designed to screen a variety of food matrices for diverse and potentially harmful chemicals, including unknown compounds, using GC/MS, LC/MS, ICP/MS and ELISA methodologies. Laboratory personnel will participate in training exercises designed to assess the ability of FERN to respond to various contamination scenarios, participate in national and regional training conferences, and assist with the validation and expansion of existing FERN methods. The laboratory will participate in an evaluation of our existing quality assurance/quality control program and address any deficiencies identified. Our quality program will be tested via our participation in FERN proficiency exercises. Specifically, the objectives that will be met include: ¿ Training of laboratory personnel in FERN analytical methodologies ¿ Participation in national and regional FERN training opportunities ¿ Provision of analytical expertise to the improvement, expansion and validation of existing FERN methods ¿ Assistance with the development of new FERN methods as the need arises ¿ Participation in FERN proficiency test programs ¿ Maintenance of existing FERN equipment ¿ Collaboration with other FERN laboratories to ensure the effectiveness of the FERN program ¿ Participation in response or surveillance exercises as the need arises ¿ Effectively communicate with other FERN laboratories via the use of eLEXNET