Training in Dengue Prevention and Control

摘要/摘要 这是对Fogarty培训赠款提案的修订，该提案名为“登革热预防和管理培训” 2009年9月提交《控制》建设国际传染病培训 在科罗拉多州立大学为墨西哥博士后和博士后学生开设的课程。这个 拟议的GIDRTP的重点是提供现代方法的关键培训，以控制 登革病毒(DENV1-4)蚊媒埃及伊蚊及其后续预防 流行登革热(DF)和登革出血热(DHF)。这两种疾病都有 在美洲出现了主要的公共卫生问题。这项建议最初是 去年与国际合作组织的申请一起提交的 传染病研究(ICIDR)拨款“可持续控制埃及伊蚊和疫情” 与合作调查员Dra A.Flores-Suarez合作 蒙特雷的UANL和来自梅里达UADY的Farfan-Ale博士获奖并于#年开始 2010年9月。因此，如果Fogerty申请获得资金，我们将继续培训 来自墨西哥的博士后和博士后以最新的方法控制Ae。 埃及伊蚊和随后的DF和DHF的预防。拟议的培训计划将是 灵活，并将允许在以下四个项目之一中进行专门的课程作业和实验室或现场项目 跟踪：1)蚊子监测和控制，2)抗药性管理，3)效应器 分子发育或4)遗传控制。尽管有这种灵活性，所有的学生都将成为 直接参与填充登革热决策支持系统，该系统正在 在CSU积极开发有关登革热患者、实验室诊断、蚊子的数据 丰度，以及实时收集的抗药性。DDSS旨在支持 通过增加其能力来实施病媒/疾病控制计划：1)收集、存储、 管理和分析与蚊子媒介和疾病相关的数据，2)提供信息 分析输出(图表、图形、地图、表格)以支持决策，以及3)实施 适合当地情况的病媒/疾病控制规划战略和方法。最终 学生也可以自己负责建立和维护DDSS 在他们返回墨西哥后，他们将被送往其他国家。

Abstract / Summary This is a revision of a Fogarty training grant proposal "Training in Dengue Prevention and Control" submitted in September of 2009 to build an international infectious disease training program for Mexican predoctoral and postdoctoral students at Colorado State University. The focus of the proposed GIDRTP is to provide critical training in modern approaches for control of the dengue virus (DENV1-4) mosquito vector Aedes aegypti and subsequent prevention of epidemic dengue fever (DF) and Dengue Hemorrhagic Fever (DHF). Both diseases have emerged as major public health problems in the Americas. This proposal was originally submitted last year in conjunction with an application for an International Collaborations in Infectious Disease Research (ICIDR) grant "Sustainable control of Aedes aegypti and epidemic dengue." That ICIDR grant, a collaboration with coinvestigators Dra A. Flores-Suarez from UANL in Monterrey, and Dr. Farfan-Ale from UADY in Merida was awarded and began in September 2010. Thus, if this Fogerty application is funded, we are poised to continue to train pre- and postdoctoral student from Mexico in the most up to date methods to control the Ae. aegypti and subsequent prevention of DF and DHF. The proposed training program will be flexible and will permit specialized coursework and laboratory or field projects in one of four tracks: 1) mosquito monitoring and control, 2) insecticide resistance management, 3) effector molecule development or 4) genetic control. Despite this flexibility all students will become directly involved in populating the Dengue Decision Support System (DDSS) which is being actively developed at CSU with data on dengue patients, laboratory diagnostics, mosquito abundance, and insecticide resistance collected in real time. The DDSS aims to support operational vector/disease control programs by increasing their capacity to: 1) collect, store, manage, and analyze mosquito vector- and disease-related data, 2) produce informative analysis outputs (charts, graphs, maps, tables) to support decision-making, and 3) implement locally appropriate vector/disease control program strategies and methodologies. Ultimately students may also become responsible for establishing and maintaining the DDSS in their own states upon their return to Mexico.