Electro-optic adaptive eyeglass for correction of presbyopia

矫正老花眼的电光自适应眼镜

• 批准号: 8549251
• 负责人: Guoqiang Li
• 金额: $ 33.88万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2015-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8549251
• 关键词: Adopted; Area; Astigmatism; Automobile Driving; Boxing; Caliber; Caring; Clinical Research; Computers; Contact Lenses; Contrast Sensitivity; Devices; Distant; Dizziness; Electronics; Elements; Eye; Eyeglasses; Feedback; Goals; Human; Intraocular lens implant device; Light; Manuals; Measures; Methods; Mono-S; Myopia; Ophthalmologist; Optics; Patients; Performance; Phase; Population; Presbyopia; Quality of life; Reaction Time; Reading; Refractive Errors; Research; Scanning; System; Techniques; Time; Vision; Visual Acuity; Visual impairment; abstracting; adaptive optics; age related; bioimaging; cost; cost effective; design; gaze; improved; lens; light weight; liquid crystal; meetings; novel; novel strategies; operation; practical application; prototype; simulation; visual performance; voltage

Electro-optic adaptive eyeglass for correction of presbyopia Abstract Presbyopia is an age-related loss of accommodation of the human eye that manifests itself as inability to shift focus from distant to near objects. More than 90% of the people over 45 need correction of presbyopia. The conventional corrective lenses (bifocal, trifocal) have been around for more than 200 years and have some drawbacks. They have a limited field of view for each vision task, requiring user to gaze down to accomplish near vision and in some cases causing dizziness and discomfort. Some users need three different eyeglasses for reading, computer, and driving. Progressive lenses cause some distortion. Recently we have demonstrated switchable diffractive liquid crystal (LC) lens with binary ON and OFF states. In the proposed project, our goal is to develop a tunable, low-cost electro-optic lens with continuous focusing powers and high optical performance for near-, intermediate-, and distance vision. The whole aperture with the same power is used for each vision task. Such a device may have revolutionary impact on the field of vision care. Existing LC lenses have an aperture of 10-15 mm, and the power can only be switched between plano and 1 diopter (D) (or 2D). The driver box is 4¿4¿2 cm3, which is bulky. They are not suitable for practical ophthalmic applications. In this study, we will develop a novel, high performance, cost-effective varifocal LC lens with a compact electronic driver and controller. The focusing power of the lens can be continuously tuned from plano to +4D by applied voltages. This range covers the typical add powers needed for presbyopes, and it allows almost all patients to use the same lens. We will fabricate lenses with an aperture around 40mm, which satisfies the requirement for practical applications. The light efficiency will be close to 100%. These three specifications have not been met before. We will design a novel closed-loop driver circuit with good reliability and high power efficiency. In addition, we will develop a minicontroller that allows change of the focus power by simply pressing a button, which is practical and reliable; in the second phase of this project, we will develop a prototype of the eyeglass that allows autofocus function. The size of the driver will be only 5¿5¿2 mm3. Clinical studies will be performed to assess how the wearers function and perceive the new spectacles. This kind of lens is promising to become an alternative of conventional area division multi-focal spectacle lenses used by presbyopes. They may have the potential of revolutionizing the field of presbyopia correction. The new eyeglass will significantly improve the quality of life for a large population. Applications can be extended to fields where varifocal lens elements with low operation voltages, relatively large diameters and fast response time are desirable. For example, a single lens of this kind can be used as a new phoropter to measure the refractive errors and visual acuity and for rapid depth scanning in three-dimensional biomedical imaging. Correction of low vision with high quality optics in the periphery will also have high impact. This would be our next focus of research.

电光自适应调节器矫正老视 摘要 老花眼是与年龄相关的人眼调节丧失，其表现为 不能将焦点从远处转移到近处。超过90%的45岁以上的人需要 矫正老花眼传统的矫正镜片（双焦点、三焦点）已经被 已经存在了200多年，也有一些缺点。它们的视野有限 对于每个视觉任务，需要用户向下凝视以实现近视力，并且在某些情况下， 引起头晕和不适。有些用户需要三种不同的眼镜来进行阅读， 电脑，驾驶。渐进镜片会引起一些变形。最近我们 展示了具有二元开和关状态的可切换衍射液晶（LC）透镜。在 我们的目标是开发一种可调的、低成本的电光透镜， 连续聚焦能力和高光学性能，适用于近、中、 远距离视觉。具有相同功率的整个光圈用于每个视觉任务。这样的 该设备可能对视力保健领域产生革命性的影响。 现有的LC镜头光圈为10-15 mm，功率只能切换 在平光和1屈光度（D）（或2D）之间。驱动器箱为4 <$4 <$2 cm 3，体积庞大。他们 不适用于实际的眼科应用。在这项研究中，我们将开发一种新的， 具有紧凑型电子驱动器的高性能、高性价比变焦LC透镜， controller.透镜的聚焦能力可以通过以下方式从平焦连续调谐到+4D 外加电压这个范围涵盖了老花眼所需的典型附加功率， 允许几乎所有患者使用相同的透镜。我们将制造带有光圈的透镜 40 mm左右，满足实际应用的要求。光效率 将接近100%。这三个规格以前都没有达到。我们将设计一 可靠性好、功率效率高的新型闭环驱动电路。另外我们 将开发一种微型控制器，只需按下一个按钮， 按钮，这是实用和可靠的;在这个项目的第二阶段，我们将开发一个 允许自动对焦功能的相机原型。驱动程序的大小将仅为 5 <$5 <$2 mm3。将进行临床研究，以评估佩戴者的功能， 看到了新的眼镜。 这种透镜有希望成为传统区域分割的替代品 老花眼使用的多焦点眼镜片。它们可能有潜力 彻底改变了老花眼矫正领域。新的机器人将大大改善 大量人口的生活质量。应用可以扩展到变焦的领域， 具有低操作电压、相对大直径和快速响应时间的透镜元件 是可取的。例如，这种类型的单个透镜可以用作新的综合屈光检查仪， 测量屈光不正和视力，并进行快速深度扫描， 三维生物医学成像。高质量光学矫正低视力 周边地区也将产生很大影响。这将是我们下一步的研究重点。