Electro-optic adaptive eyeglass for correction of presbyopia

矫正老花眼的电光自适应眼镜

• 批准号: 7993737
• 负责人: Guoqiang Li
• 金额: $ 28.64万
• 依托单位: UNIVERSITY OF MISSOURI-ST. LOUIS
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7993737
• 关键词: Adopted; Area; Astigmatism; Automobile Driving; Boxing; Caliber; Caring; Clinical Research; Computers; Contrast Sensitivity; Devices; Distant; Dizziness; Electronics; Elements; Eye; Eyeglasses; Feedback; Goals; Human; Intraocular lens implant device; Light; Manuals; Measures; Methods; Mono-S; Myopia; Ophthalmologist; Optics; Patients; Performance; Phase; Population; Presbyopia; Quality of life; Reaction Time; Reading; Refractive Errors; Research; Scanning; System; Techniques; Time; Vision; Visual Acuity; Visual impairment; adaptive optics; age related; bioimaging; cost; design; gaze; improved; lens; light weight; liquid crystal; meetings; novel; novel strategies; operation; practical application; prototype; public health relevance; simulation; visual performance; voltage

DESCRIPTION (provided by applicant): Presbyopia is an age-related loss of accommodation of the human eye that manifests itself as inability to shift focus from distant to near objects. More than 90% of the people over 45 need correction of presbyopia. The conventional corrective lenses (bifocal, trifocal) have been around for more than 200 years and have some drawbacks. They have a limited field of view for each vision task, requiring user to gaze down to accomplish near vision and in some cases causing dizziness and discomfort. Some users need three different eyeglasses for reading, computer, and driving. Progressive lenses cause some distortion. Recently we have demonstrated switchable diffractive liquid crystal (LC) lens with binary ON and OFF states. In the proposed project, our goal is to develop a tunable, low-cost electro-optic lens with continuous focusing powers and high optical performance for near-, intermediate-, and distance vision. The whole aperture with the same power is used for each vision task. Such a device may have revolutionary impact on the field of vision care. Existing LC lenses have an aperture of 10-15 mm, and the power can only be switched between plano and 1 diopter (D) (or 2D). The driver box is 4W4W2 cm3, which is bulky. They are not suitable for practical ophthalmic applications. In this study, we will develop a novel, high performance, cost-effective varifocal LC lens with a compact electronic driver and controller. The focusing power of the lens can be continuously tuned from plano to +4D by applied voltages. This range covers the typical add powers needed for presbyopes, and it allows almost all patients to use the same lens. We will fabricate lenses with an aperture around 40mm, which satisfies the requirement for practical applications. The light efficiency will be close to 100%. These three specifications have not been met before. We will design a novel closed-loop driver circuit with good reliability and high power efficiency. In addition, we will develop a minicontroller that allows change of the focus power by simply pressing a button, which is practical and reliable; in the second phase of this project, we will develop a prototype of the eyeglass that allows autofocus function. The size of the driver will be only 5W5W2 mm3. Clinical studies will be performed to assess how the wearers function and perceive the new spectacles. This kind of lens is promising to become an alternative of conventional area division multi-focal spectacle lenses used by presbyopes. They may have the potential of revolutionizing the field of presbyopia correction. The new eyeglass will significantly improve the quality of life for a large population. Applications can be extended to fields where varifocal lens elements with low operation voltages, relatively large diameters and fast response time are desirable. For example, a single lens of this kind can be used as a new phoropter to measure the refractive errors and visual acuity and for rapid depth scanning in three-dimensional biomedical imaging. Correction of low vision with high quality optics in the periphery will also have high impact. This would be our next focus of research. PUBLIC HEALTH RELEVANCE: The proposed electro-optic adaptive eyeglass allows correction of near-, intermediate-, and distance vision. The lens has high diffraction efficiency, larger aperture, large tunable range, high optical quality, good response time, and low driving voltages. The focusing power can be continuously tuned by the applied voltages. The cost can be comparable or lower than progressive lenses. This kind of lens is promising to replace conventional area-division multi-focal spectacle lenses used by presbyopes. They have the potential of revolutionizing the field of presbyopia correction. Needlessly to say, the new eyeglass will significantly improve the quality of life for a large portion of the population. Applications can be extended to fields where varifocal lens elements with low operation voltages, relatively large diameters and fast response time are desirable. For example, a single lens of this kind can be used as a new phoropter to measure the refractive errors and visual acuity. The current phoropters are bulky and require the ophthalmologist/technician to manually adjust the add lenses, which is also time consuming. The new phoropter is compact, light weight, and easy to use. Correction of low vision with high quality optics in the periphery will also have high impact. This would be our next focus of research.

描述(申请人提供)：老花眼是一种与年龄相关的人眼调节能力的丧失，表现为无法将焦点从远处的物体转移到近距离的物体。超过90%的45岁以上的人需要矫正老花眼。传统的矫正镜片(双焦、三焦)已有200多年的历史，但也存在一些缺陷。他们对每个视觉任务都有有限的视野，需要用户向下凝视才能完成近视，在某些情况下会导致头晕和不适。一些用户需要三种不同的眼镜来阅读、电脑和驾驶。渐进式镜片会造成一些失真。最近，我们展示了具有二元开启和关闭状态的可切换衍射液晶(LC)透镜。在拟议的项目中，我们的目标是开发一种可调谐的、低成本的电光透镜，具有连续的聚焦功率和高的光学性能，用于近、中、远视觉。每个视觉任务都使用相同功率的整个光圈。这样的设备可能会对视力护理领域产生革命性的影响。现有的LC透镜的光圈为10-15毫米，只能在平面和1屈光度(D)(或2D)之间切换。驱动器盒为4W4W2厘米，体积较大。它们不适合实际的眼科应用。在这项研究中，我们将开发一种新型的、高性能、高性价比的变焦LC透镜，它具有紧凑的电子驱动器和控制器。透镜的焦距可以通过外加电压从平坦到+4D连续调谐。这一范围涵盖了老花眼所需的典型增加倍数，它允许几乎所有患者使用相同的镜片。我们将制作口径在40 mm左右的透镜，满足实际应用的要求。光效将接近100%。这三种规格以前都没有达到过。我们将设计一种新型的闭环驱动电路，具有良好的可靠性和高功率效率。此外，我们将开发一种微型控制器，只需按一下按钮就可以改变对焦功率，实用可靠；在这个项目的第二阶段，我们将开发一种具有自动对焦功能的眼镜原型。驱动器的大小将只有5W5W2mm3。将进行临床研究，以评估佩戴者的功能和对新眼镜的感知。这种镜片有望成为老人家使用的传统面分式多焦镜的替代品。它们可能会给老花眼矫正领域带来革命性的变化。这种新型眼镜将显著提高广大人口的生活质量。应用可以扩展到需要具有低操作电压、相对较大直径和快速响应时间的变焦透镜元件的领域。例如，这种类型的单个透镜可以作为一种新的屈光度来测量屈光不正和视力，并用于三维生物医学成像中的快速深度扫描。用高质量的周边光学矫正低视力也将产生很大的影响。这将是我们下一个研究的重点。 与公共健康相关：拟议的电光自适应眼镜允许矫正近、中、远视力。该透镜具有衍射效率高、口径大、调谐范围大、光学质量高、响应时间长、驱动电压低等特点。聚焦功率可以通过施加的电压连续调节。成本可以与渐进式镜片相当或更低。这种镜片有望取代传统的老人家使用的面分式多焦眼镜镜片。它们有可能给老视矫正领域带来革命性的变化。不用说，这种新型眼镜将显著提高大部分人的生活质量。应用可以扩展到需要具有低操作电压、相对较大直径和快速响应时间的变焦透镜元件的领域。例如，这种类型的单个透镜可以作为一种新的验光镜来测量屈光不正和视力。目前的验光仪很笨重，需要眼科医生/技师手动调整增加的镜片，这也很耗时。这款新型触摸屏结构紧凑、重量轻、使用方便。用高质量的周边光学矫正低视力也将产生很大的影响。这将是我们下一个研究的重点。