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Synthesis and Nanoformulation Core

Synthesis and Nanoformulation Core
合成和纳米制剂核心
批准号：
8554598
负责人：
SHANTU G AMIN
金额：
$15.06万
依托单位：
PENNSYLVANIA STATE UNIV HERSHEY MED CTR
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
项目状态：
已结题
起止时间：
2013-09-10 至 2018-08-31
来源：
https://reporter.nih.gov/project-details/8554598
关键词：
ADME StudyAnalytical ChemistryBiologicalCeramidesChemical AgentsChemicalsDrug FormulationsEncapsulatedIndividualLiposomesMetabolismMolecularN-caproylsphingosineRadiolabeledSKI geneSphingolipidsTamoxifenTechniquesanalogbaseexperiencegalactosylgalactosylglucosylceramidaseinhibitor/antagonistkinase inhibitormembernanoformulationnanoliposomenew therapeutic targetnovelprogramsradiotracerresearch studysphingosine kinase

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中文摘要
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英文摘要
The Synthesis and Nanoformulation Core (SNC) will supply ceramide analogs, acid ceramidase (AC) inhibitors, sphingosine kinase inhibitors, and tamoxifen metabolites essential to the members of this Program Project. In addition, the Core will also provide liposomal formulations of C6-ceramide derivatives, acid ceramidase inhibitors, sphingosine kinase inhibitor SKI-178, and tamoxifen metabolites to the Projects 1, 2, 3, and 4, respectively. Furthermore, the Core will also synthesize [^H] AC inhibitors and [^
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Targeting Aldehyde Dehydrogenase for Cancer Prevention
Targeting Aldehyde Dehydrogenase for Cancer Prevention
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CORE--ORGANIC SYNTHESIS FACILITY
  • 批准号：
    6605471
  • 项目类别：
  • 资助金额：
    $24.29万
  • 财政年份：
    2002
  • 负责人：
    SHANTU G AMIN
  • 依托单位：
    INSTITUTE FOR CANCER PREVENTION
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