Insulin-regulated aminopeptidase, glucose and memory

我们之前已经证明，IRAP的抑制剂可以改善正常和记忆受损动物的记忆任务表现，目前正在开发以IRAP为靶点的新的记忆丧失治疗方法。在这项研究中，我们将研究IRAP的生理作用及其与细胞内蛋白的关系。所获得的知识将为大脑如何处理记忆提供洞察力，并确认IRAP抑制剂作为治疗记忆缺陷的药物的适用性。

We have previously shown that inhibitors of IRAP improve performance in memory tasks in normal and memory impaired animals and are currently developing new treatments for memory loss using IRAP as a target. In this study, we will investigate the physiological roles of IRAP and its association with intracellular proteins. The knowledge obtained will provide insights of how the brain process memory and confirm the suitability of IRAP inhibitors as drugs for treating memory deficits.