Transdisciplinary Training In Cardiovascular Research

心血管研究的跨学科培训

• 批准号: 8608216
• 负责人: CATARINA I. KIEFE
• 金额: $ 19.86万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8608216
• 关键词: Cardiovascular system; Research; Training

We propose a new transdisciplinary cardiovascular sciences training program at the University of Massachusetts Medical School (UMMS) that will encompass the full spectrum of research from basic to implementation science. We will provide skills and experiences that position our trainees to uncover new knowledge that can be translated and implemented into the clinical arena for societal benefit; and inspire basic research based on human needs. This application is a collaborative effort between the Division of Cardiovascular Medicine (in the Department of Medicine) and the Department of Quantitative Health Sciences, and will involve multiple UMMS campus-wide resources. Traditionally, research training has been fragmented, with basic, clinical, and translational efforts often performed in isolation. Current challenges to improve efficiency in research and health care delivery mandate new paradigms. In this context, collaboration between bench and non-bench scientists has led to "team science" as an increasing necessity to meet these challenges. For this reason, our current application is transdisciplinary - a term describing investigators that work together to expand beyond discipline-based concepts, theories, and methods as a means to address a common research topic. Thus, this proposal will offer trainees a novel mentoring scheme by a priori establishing mentorship teams that break boundaries between individual disciplines. The overarching goal of the proposed T32 program is to build a cardiovascular training infrastructure for individuals who will be both independent investigators and team scientists. Each trainee will have the access to expertise from the basic, clinical/translational, public health, and implementation science arenas, and mentors from the T0/T1 and T2+ ends of the spectrum to provide a unique perspective on both the importance and the application of research results. This Program will include collaboration with highly successful scientists, independent research experiences, and novel academic programs. We have a Masters of Science in Clinical Investigation (MSCI) program for clinician-postdoctoral trainees and multiple PhD programs in the Graduate School of Biomedical Sciences for pre-doctoral trainees. This breadth of mentors, scientific disciplines, and academic programs offers the flexibility to individualize each trainee's experience while providing a strong methodological foundation. Each trainee will identify a major research focus, design and complete a research project in close collaboration with an experienced lead mentor and team, and will submit the results for peer-reviewed publication. Consistent with our transdisciplinary approach, our proposed program also includes early mentor training via mentoring teams across the continuum of faculty levels and disciplinary perspectives. The aims of our program are to: i) Establish a cardiovascular research training program across basic, clinical, and population health disciplines geared towards translating research into effective clinical practice and policy, as well as generating new questions spanning the entire spectrum of cardiovascular disease (CVD) research; ii) Recruit pre-and post- doctoral trainees resulting in a diverse trainee pool with respect to sociodemographic characteristics, clinical background, and disciplinary perspective; iii) Provide trainees with the individual mentoring, academic training, and technical skills necessary to ensure their success as independent investigators as well as contributors to team science; and iv) Provide "hands on" research experience within transdisciplinary teams that builds on the strengths of the current environment of linkages between UMMS Departments, Centers, and Institutes. This program represents an interdepartmental joint effort. It will be co-directed by John F. Keaney, Jr., MD, Chief of Cardiovascular Medicine in the Department of Medicine (DOM) at UMMS and Catarina Kiefe, MD, PhD, Chair of the UMMS Department of Quantitative Health Sciences (QHS). These co- Directors are leaders in T0/T1 and T2+ translational research, respectively. The successful implementation of this program will greatly enhance the research environment at UMMS and position our graduates to the be researchers of tomorrow.!

我们在加州大学提出了一个新的跨学科心血管科学培训计划 马萨诸塞州医学院(UMMS)将涵盖从基础到 实施科学。我们将提供技能和经验，使我们的学员能够发现 可转化并应用于临床领域以造福社会的新知识；以及 激发基于人类需求的基础研究。此应用程序是 心血管内科(内科)和 定量健康科学，并将涉及多个UMMS校园范围的资源。 传统上，研究培训一直是零散的，基础、临床和翻译工作往往 孤立地执行的。当前在提高研究和医疗保健提供效率方面的挑战 要求建立新的范式。在这方面，长椅和非长椅科学家之间的合作导致了 将“团队科学”作为应对这些挑战的日益必要的手段。因此，我们目前 应用程序是跨学科的-这个术语描述的是合作扩展到更远的研究人员 以学科为基础的概念、理论和方法，作为解决共同研究主题的手段。 因此，这项建议将通过先验地建立导师关系来为学员提供一种新颖的导师方案 打破各个学科之间界限的团队。拟议的T32的首要目标是 该计划是为既独立又独立的个人建立心血管训练基础设施 调查人员和团队科学家。每个受训人员都将有机会从基本的、 临床/翻译、公共卫生和实施科学领域，以及来自T0/T1的导师 和T2+系列的两端，提供了关于重要性和 研究成果的应用。 该计划将包括与非常成功的科学家合作，独立研究 体验和新奇的学术项目。我们有临床研究的理学硕士学位 (MSCI)临床医生-博士后实习生项目和研究生院的多个博士项目 面向博士前实习生的生物医学科学专业。导师的广度，科学学科，以及 学术课程提供了灵活性，使每个学员的体验个性化，同时提供 扎实的方法论基础。每个实习生将确定一个主要的研究重点、设计和 与经验丰富的首席导师和团队密切合作完成研究项目，并将 将结果提交给同行评议的出版物。与我们的跨学科方法一致，我们的 拟议的计划还包括通过指导团队进行的早期指导培训 教师水平和学科观点。 我们计划的目标是：i)建立一个涵盖基础、 临床和人口健康学科致力于将研究转化为有效的临床 实践和政策，以及在整个范围内产生新的问题 心血管疾病(CVD)研究；ii)招募博士后和博士后实习生，导致不同的 关于社会人口学特征、临床背景和学科的实习生集合 观点；三)为受训者提供个人指导、学术培训和技术技能 确保他们作为独立调查人员和团队贡献者取得成功所必需的 科学；以及四)在跨学科团队内提供“亲身实践”的研究经验 当前UMMS部门、中心和中心之间的联系环境的优势 研究所。 这项计划代表了部门间的共同努力。该片将由小约翰·F·基尼联合执导， 医学博士，UMMS和卡塔琳娜大学医学部(DOM)心血管内科主任 基夫，医学博士，密歇根大学定量健康科学部(QHS)主任。这些共同的- 导演分别是T0/T1和T2+翻译研究的领导者。成功者 该计划的实施将极大地改善UMMS的研究环境和职位 我们的毕业生将成为未来的研究人员。