Transdisciplinary Training In Cardiovascular Research

心血管研究的跨学科培训

• 批准号: 9309037
• 负责人: CATARINA I. KIEFE
• 金额: $ 35.43万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9309037
• 关键词: Cardiovascular system; Research; Training

DESCRIPTION (provided by applicant): We propose a new transdisciplinary cardiovascular sciences training program at the University of Massachusetts Medical School (UMMS) that will encompass the full spectrum of research from basic to implementation science. We will provide skills and experiences that position our trainees to uncover new knowledge that can be translated and implemented into the clinical arena for societal benefit; and inspire basic research based on human needs. This application is a collaborative effort between the Division of Cardiovascular Medicine (in the Department of Medicine) and the Department of Quantitative Health Sciences, and will involve multiple UMMS campus-wide resources. Traditionally, research training has been fragmented, with basic, clinical, and translational efforts often performed in isolation. Current challenges to improve efficiency in research and health care delivery mandate new paradigms. In this context, collaboration between bench and non-bench scientists has led to "team science" as an increasing necessity to meet these challenges. For this reason, our current application is transdisciplinary - a term describing investigators that work together to expand beyond discipline-based concepts, theories, and methods as a means to address a common research topic. Thus, this proposal will offer trainees a novel mentoring scheme by a priori establishing mentorship teams that break boundaries between individual disciplines. The overarching goal of the proposed T32 program is to build a cardiovascular training infrastructure for individuals who will be both independent investigators and team scientists. Each trainee will have the access to expertise from the basic, clinical/translational, public health, and implementation science arenas, and mentors from the T0/T1 and T2+ ends of the spectrum to provide a unique perspective on both the importance and the application of research results. This Program will include collaboration with highly successful scientists, independent research experiences, and novel academic programs. We have a Masters of Science in Clinical Investigation (MSCI) program for clinician-postdoctoral trainees and multiple PhD programs in the Graduate School of Biomedical Sciences for pre-doctoral trainees. This breadth of mentors, scientific disciplines, and academic programs offers the flexibility to individualize each trainee's experience while providing a strong methodological foundation. Each trainee will identify a major research focus, design and complete a research project in close collaboration with an experienced lead mentor and team, and will submit the results for peer-reviewed publication. Consistent with our transdisciplinary approach, our proposed program also includes early mentor training via mentoring teams across the continuum of faculty levels and disciplinary perspectives. The aims of our program are to: i) Establish a cardiovascular research training program across basic, clinical, and population health disciplines geared towards translating research into effective clinical practice and policy, as wel as generating new questions spanning the entire spectrum of cardiovascular disease (CVD) research; ii) Recruit pre-and post- doctoral trainees resulting in a diverse trainee pool with respect to sociodemographic characteristics, clinical background, and disciplinary perspective; iii) Provide trainees with the individual mentoring, academic training, and technical skills necessary to ensure their success as independent investigators as well as contributors to team science; and iv) Provide "hands on" research experience within transdisciplinary teams that builds on the strengths of the current environment of linkages between UMMS Departments, Centers, and Institutes. This program represents an interdepartmental joint effort. It will be co-directed by John F. Keaney, Jr., MD, Chief of Cardiovascular Medicine in the Department of Medicine (DOM) at UMMS and Catarina Kiefe, MD, PhD, Chair of the UMMS Department of Quantitative Health Sciences (QHS). These co- Directors are leaders in T0/T1 and T2+ translational research, respectively. The successful implementation of this program will greatly enhance the research environment at UMMS and position our graduates to the be researchers of tomorrow.

描述（由申请人提供）：我们在马萨诸塞州医学院（UMMS）提出了一个新的跨学科心血管科学培训计划，该计划将涵盖从基础科学到实施科学的全方位研究。我们将提供技能和经验，使我们的学员能够发现新的知识，这些知识可以转化并应用于临床竞技场，以造福社会;并激发基于人类需求的基础研究。该应用程序是心血管医学部（医学系）和定量健康科学部之间的合作努力，并将涉及多个UMMS校园范围内的资源。传统上，研究培训是分散的，基础，临床和翻译工作往往是孤立进行的。当前提高研究和医疗保健提供效率的挑战要求新的范式。在这种情况下，实验室和非实验室科学家之间的合作导致“团队科学”成为应对这些挑战的日益必要的手段。出于这个原因，我们目前的应用程序是跨学科的-一个术语描述的研究人员共同努力，以扩大超越学科为基础的概念，理论和方法，作为一种手段，以解决一个共同的研究课题。因此，这项建议将为学员提供一个新的指导计划，先验建立导师团队，打破个别学科之间的界限。T32计划的总体目标是为独立研究者和团队科学家建立心血管训练基础设施。每个学员都将获得来自基础，临床/转化，公共卫生和实施科学领域的专业知识，以及来自T0/T1和T2+两端的导师，以提供对研究成果的重要性和应用的独特视角。该计划将包括与非常成功的科学家合作，独立的研究经验和新颖的学术计划。我们有一个临床研究科学硕士（MSCI）计划的临床医生，博士后学员和多个博士课程在生物医学科学研究生院的博士前学员。导师，科学学科和学术课程的这种广度提供了灵活性，以个性化每个学员的经验，同时提供了强大的方法论基础。每位学员将确定一个主要的研究重点，与经验丰富的主要导师和团队密切合作，设计和完成一个研究项目，并将结果提交同行评审出版。与我们的跨学科方法相一致，我们提出的计划还包括通过指导团队在教师水平和学科观点的连续体早期导师培训。我们的计划的目的是：i）建立一个跨基础，临床和人口健康学科的心血管研究培训计划，旨在将研究转化为有效的临床实践和政策，以及产生跨越心血管疾病（CVD）研究的整个频谱的新问题;二）招聘博士前和博士后学员，从而在社会人口特征、临床背景和学科观点方面形成多样化的学员库; iii）为学员提供个人指导，学术培训和必要的技术技能，以确保他们作为独立调查人员以及团队科学的贡献者取得成功; iv）在跨学科团队中提供“动手”研究经验，该团队建立在UMMS部门，中心和研究所之间联系的当前环境的优势之上。这个项目是一个跨部门的共同努力。它将由约翰·F。小基尼医学博士，UMMS医学系（DOM）心血管内科主任和卡塔里纳Kiefe，医学博士，博士，UMMS定量健康科学系（QHS）主任。这些共同主任分别是T0/T1和T2+转化研究的领导者。该计划的成功实施将大大提高UMMS的研究环境，并将我们的毕业生定位为明天的研究人员。