The Psychobiology of Trauma and Resilience Across the Lifespan

描述(由申请者提供)：本申请旨在为在蒙特利尔(2010年11月4日至6日)、洛杉矶(2012年11月1日至3日)和待定地点(2014年11月1日至3日)举行的国际创伤应激研究学会(ISTSS)第26届、第28届和第30届年会提供资金。我们将复制我们目前由NIMH资助的会议赠款中使用的成功模式。每次会议都有解决重要创伤应激问题的基础科学和临床科学的核心科学规划。儿童虐待、人际暴力、灾难、恐怖主义和战争等潜在创伤性事件的发生率很高，接触潜在创伤性事件会增加患创伤后应激障碍、抑郁症、药物使用障碍和实施暴力的风险。会议计划将解决更好地进行创伤应激研究和将临床研究转化为临床实践的障碍，其中包括：1)所研究的创伤应激类型分散；2)缺乏整合创伤应激研究的整合，纳入遗传、分子、行为、心理和公共健康层面的分析和观点；3)由于在生命的后期暴露于创伤后应激障碍，未能考虑到童年经历的创伤应激对创伤后应激障碍风险的发育影响；4)基础科学研究向临床研究、临床研究向临床和公共卫生实践的转化很差。具体目标是：1)组织年度会议，让研究、临床实践和政策受众参与讨论对创伤后应激障碍和相关疾病的风险、复原力、预防和治疗的遗传、分子、行为、心理和社会影响，以努力鼓励更好的研究和改善护理的发展；2)整合来自不同角度和分析水平的知识，以提高科学知识和获得科学信息的临床实践；以及3)通过《创伤应激杂志》的年度特别栏目向科学界传播有关关键会议主题和演示的信息。在P.I.和一个项目协调委员会的指导下，2010年、2012年和2014年年会将有20%的内容专门讨论这些问题。将选择主旨演讲者、全体演讲者和其他演讲者，以确保有足够的此类节目。示范演示文稿将在ISTSS网站上进行总结，每年将在JTS上发表一个以这些文稿为基础的特别版面。协调委员会将确保该方案包括妇女和传统上代表性不足的种族/少数民族。将获得与会者的调查反馈、媒体报道的数据以及发表在JTS特别版块上的文章的引用数据。注：与NIMH关于会议赠款的新政策一致，我们将使用额外的赠款资金来实现完全可持续的年度会议，其中纳入了赠款可能带来的计划增强，因此不需要额外申请NIMH会议赠款资金。

DESCRIPTION (provided by applicant): This application seeks funding for scientific presentations at the 26th, 28th, and 30th Annual Meetings of the International Society for Traumatic Stress Studies (ISTSS) to be held in Montreal (November 4-6, 2010), Los Angeles (November 1-3, 2012) and a site to be determined (November, 2014). We will replicate the successful model used in our current NIMH-funded conference grant. Each meeting has a core of scientific programming of basic and clinical science addressing important traumatic stress issues. The prevalence of exposure to potentially traumatic events (PTEs) such as child maltreatment, interpersonal violence, disasters, terrorism, and war is high, and exposure to PTEs increases risk of PTSD, depression, substance use disorders and perpetration of violence. Programming at the meetings will address barriers to better traumatic stress research and translation of clinical research to clinical practice that include: 1) fragmentation with respect to the types of PTEs studied; 2) lack of integration of traumatic stress research that incorporates genetic, molecular, behavioral, psychological, and public health levels of analysis and perspective; 3) failure to consider the developmental impact of PTEs experienced during childhood on risk for PTSD given exposure to PTEs occurring at later points during the lifespan; and 4) poor translation of basic science research to clinical research and of clinical research to clinical and public health practice. Specific aims are to: 1) organize annual meetings that engage research, clinical practice, and policy audiences in discussions about genetic, molecular, behavioral, psychological, and social influences on risk, resilience, prevention, and treatment of PTSD and related disorders in an effort to encourage development of better research and improved care; 2) integrate knowledge from these different perspectives and levels of analysis to improve scientific knowledge and scientifically informed clinical practice; and 3) disseminate information about key meeting themes and presentations to the scientific community via annual special sections in the Journal of Traumatic Stress. Under the direction of the P.I. and a Project Coordinating Committee, 20% of the content of the 2010, 2012, and 2014 Annual Meetings will be devoted to these issues. Keynote speakers, plenary speakers, and other presentations will be selected to insure that there is adequate programming of this type. Exemplary presentations will be summarized on the ISTSS website, and a special section based on these presentations will be published in JTS each year. The Coordinating Committee will insure that the program includes women and traditionally underrepresented racial/ethnic minorities. Survey feedback from meeting participants, data on media coverage, and citation data on articles published in Special Section of the JTS will be obtained. Note: Consistent with the new NIMH policy on conference grants, we will use the additional grant funding to achieve a fully sustainable annual meeting that incorporates program enhancements made possible by the grant so that no additional requests for NIMH conference grant funding will be necessary.