The Psychobiology of Trauma and Resilience Across the Lifespan

描述（由申请人提供）：本申请寻求在第26届、第28届和第30届国际创伤应激研究学会（ISTSS）年会上的科学报告的资金，该年会将在蒙特利尔（2010年11月4日至6日）、洛杉矶（2012年11月1日至3日）和待定地点（2014年11月）举行。我们将复制我们目前NIMH资助的会议补助金中使用的成功模式。每次会议都有一个基础和临床科学的核心科学方案，处理重要的创伤压力问题。暴露于潜在创伤性事件（PTE），如虐待儿童，人际暴力，灾难，恐怖主义和战争的患病率很高，暴露于PTE会增加PTSD，抑郁症，物质使用障碍和暴力行为的风险。会议的规划将解决更好的创伤应激研究和临床研究转化为临床实践的障碍，包括：1）所研究的PTE类型的碎片化; 2）缺乏创伤应激研究的整合，包括遗传，分子，行为，心理和公共卫生水平的分析和观点; 3）未能考虑儿童时期经历的PTE对PTSD风险的发育影响，因为在生命后期暴露于PTE;以及4）基础科学研究向临床研究以及临床研究向临床和公共卫生实践的转化不良。具体目标是：1）组织年会，让研究、临床实践和政策受众参与讨论遗传、分子、行为、心理和社会对PTSD和相关疾病的风险、恢复力、预防和治疗的影响，以鼓励更好的研究和改善护理; 2）从这些不同的角度和分析水平整合知识，以提高科学知识和科学知情的临床实践; 3）通过《创伤压力杂志》的年度专题部分向科学界传播有关关键会议主题和报告的信息。在私家侦探的指导下。和项目协调委员会，2010年、2012年和2014年年会的20%内容将专门讨论这些问题。将选择主旨发言人、全体会议发言人和其他演讲，以确保有足够的此类节目。将在ISTS网站上对示范性发言进行总结，每年将在JTS上发表基于这些发言的特别部分。协调委员会将确保该方案包括妇女和传统上代表性不足的少数种族/族裔。将获得与会者的调查反馈、媒体报道数据以及JTS特别部分发表的文章的引用数据。注意事项：与新的NIMH会议赠款政策一致，我们将使用额外的补助金资金来实现完全可持续的年度会议，其中包括由补助金提供的计划增强功能，因此不需要额外的NIMH会议补助金资金请求。

DESCRIPTION (provided by applicant): This application seeks funding for scientific presentations at the 26th, 28th, and 30th Annual Meetings of the International Society for Traumatic Stress Studies (ISTSS) to be held in Montreal (November 4-6, 2010), Los Angeles (November 1-3, 2012) and a site to be determined (November, 2014). We will replicate the successful model used in our current NIMH-funded conference grant. Each meeting has a core of scientific programming of basic and clinical science addressing important traumatic stress issues. The prevalence of exposure to potentially traumatic events (PTEs) such as child maltreatment, interpersonal violence, disasters, terrorism, and war is high, and exposure to PTEs increases risk of PTSD, depression, substance use disorders and perpetration of violence. Programming at the meetings will address barriers to better traumatic stress research and translation of clinical research to clinical practice that include: 1) fragmentation with respect to the types of PTEs studied; 2) lack of integration of traumatic stress research that incorporates genetic, molecular, behavioral, psychological, and public health levels of analysis and perspective; 3) failure to consider the developmental impact of PTEs experienced during childhood on risk for PTSD given exposure to PTEs occurring at later points during the lifespan; and 4) poor translation of basic science research to clinical research and of clinical research to clinical and public health practice. Specific aims are to: 1) organize annual meetings that engage research, clinical practice, and policy audiences in discussions about genetic, molecular, behavioral, psychological, and social influences on risk, resilience, prevention, and treatment of PTSD and related disorders in an effort to encourage development of better research and improved care; 2) integrate knowledge from these different perspectives and levels of analysis to improve scientific knowledge and scientifically informed clinical practice; and 3) disseminate information about key meeting themes and presentations to the scientific community via annual special sections in the Journal of Traumatic Stress. Under the direction of the P.I. and a Project Coordinating Committee, 20% of the content of the 2010, 2012, and 2014 Annual Meetings will be devoted to these issues. Keynote speakers, plenary speakers, and other presentations will be selected to insure that there is adequate programming of this type. Exemplary presentations will be summarized on the ISTSS website, and a special section based on these presentations will be published in JTS each year. The Coordinating Committee will insure that the program includes women and traditionally underrepresented racial/ethnic minorities. Survey feedback from meeting participants, data on media coverage, and citation data on articles published in Special Section of the JTS will be obtained. Note: Consistent with the new NIMH policy on conference grants, we will use the additional grant funding to achieve a fully sustainable annual meeting that incorporates program enhancements made possible by the grant so that no additional requests for NIMH conference grant funding will be necessary.