Administrative Core

行政核心将负责本计划的所有管理工作。这里提出的计划包含3个独立但相互关联的项目和2个科学核心，将开发3种不同的策略，以提供能够转录抑制和指导HIV-1或CCR 5趋化因子共受体切除的非编码RNA到HIV-1感染的细胞或HIV-1感染的免疫细胞。行政核心将通过以下方式发挥作用：监督整个项目的财政、行政和法律的责任;促进不同研究人员及其各自项目之间的互动;并负责确认所有研究都以最佳方式进行。 道德的方式。因此，行政核心的作用是该方案成功的必要条件。 行政核心的具体目标是： (1)协调项目的行政和财务要求。 (2)监督和促进项目的科学进展。 (3)监督项目内每个项目成果的传播和共享。

The administrative core will be responsible for all administration of this program. The program proposed here contains 3 independent yet linked projects and 2 scientific cores that will develop 3 different strategies to deliver non-coding RNAs capable of transcriptionally suppressing and directing the excising of HIV-1 or the CCR5 chemokine co-receptor to either HIV-1 infected cells or those immune cells targeted for infection by HIV-1. The administrative core will function by: Overseeing the fiscal, administrative, and legal responsibilities for the entire program; fostering interactions between the different investigators and their respective projects; and assuming responsibility for confirming that all research is conducted in an optimal and ethical manner. As such the role of the administrative core is integral to the success of this program. The specific aims of the administrative core are: (1) Coordinate administrative and fiscal requirements of the program. (2) Supervise and foster the scientific progress of the program. (3) Oversee the dissemination and sharing of the results from each project within the program.