Neural Correlates of the Mirror Neuron System

镜像神经元系统的神经相关性

• 批准号: 8701315
• 负责人: Nathan A Fox
• 金额: $ 21.76万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8701315
• 关键词: 7 year old; Adult; Age; Age-Months; Animals; Behavior; Behavior assessment; Behavioral; Brain; Cells; Child; Childhood; Code; Cognitive; Cognitive Science; Development; Electrodes; Electroencephalogram; Electroencephalography; Elements; Ethology; Frequencies; Functional Magnetic Resonance Imaging; Goals; Human; Infant; Instruction; Investigation; Knowledge; Laboratories; Life; Link; Location; Macaca mulatta; Maryland; Measurement; Methods; Motor; Neonatal; Neurosciences; Newborn Infant; Pattern; Perception; Play; Process; Property; Reporting; Research; Research Personnel; Role; Sampling; Scalp structure; Social Behavior; Stimulus; System; Testing; Time; Universities; Videotape; Visual attention; Work; awake; base; cognitive neuroscience; comparative; developmental psychology; infancy; interest; mirror neuron; mirror neuron system; neuroimaging; neuromechanism; neuron development; neurophysiology; nonhuman primate; programs; relating to nervous system; research study; response; skills; social; social cognition

PROJECT SUMMARY (See Instructions): A fundamental issue in cognitive neuroscience is how the brain is able to encode others' actions and intentions. In this perspective one of the most important advances of our knowledge on how these processes can take place in the cortex is the discovery of mirror neurons. The main conceptual breakthrough open by their discovery is that perceptual and motor processes share a common code. The proposed research will investigate, with non-invasive electroencephalography methods, the emergence of the MN system in infancy and young children. It will compare the EEG activity depicted by specific frequency bands in infants with that of children and adults in which the MNs has been widely studied. Acquisition of EEG will be combined with a careful behavioral assessment of subjects in order to test the hypothesis that MNs are at the basis of specific matching behaviors that are important landmarks in the development of perception action relations. We will as well, carry out experiments in non-human primates to identify these EEG rhythms in infant Rhesus Macaque and to link, for the first time, single cell recordings of mirror neurons to the ongoing EEG.

项目总结(见说明)： 认知神经科学的一个基本问题是大脑如何能够对他人的行为和意图进行编码。从这个角度来看，我们关于这些过程如何在大脑皮层发生的知识最重要的进展之一是发现了镜像神经元。主要的概念突破是由 他们的发现是，知觉和运动过程共享一个共同的代码。这项拟议的研究将使用非侵入性脑电图方法，调查婴儿和幼儿MN系统的出现。它将比较婴儿特定频段所描述的脑电活动与 在儿童和成人中，MNS已被广泛研究。EEG的获得将与对受试者的仔细行为评估相结合，以检验MN是基于特定匹配行为的假设，而特定匹配行为是知觉-行动关系发展的重要标志。我们会 此外，在非人类灵长类动物身上进行实验，以识别婴儿猕猴的脑电节律，并首次将镜像神经元的单细胞记录与正在进行的脑电联系起来。