Trajectories of Behavioral Inhibition and Risk for Anxiety

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The parent grant, Trajectories of behavioral inhibition and risk for anxiety (U01MH093349), examines the developmental pathways from early fearful temperament, Behavioral Inhibition (BI), to anxiety emerging during late adolescence. Although BI is one of the best early predictors for later anxiety, not all children with a history of BI go on to develop clinically significant anxiety, making it critical to identify the mechanisms that differentiate adolescents who struggle from those who adapt. To understand variability in outcomes, the parent grant examines how specific internal (e.g., reactive vs proactive cognitive control) and external (e.g., supportive friendships) factors, assessed during mid-adolescence (age 15), serve to exacerbate or mitigate responses to social challenges. Finally, the parent grant examines the link between response to social challenges at age 18 and the development of psychopathology by late adolescence (age 18), within a large sample of adolescents. Specifically, social interactions between the target participants and unfamiliar peers are observed, information regarding social relationships is obtained, and psychiatric status is evaluated. This administrative supplement requests funds for subject compensation so that we may conduct the social interactions, administer questionnaires regarding social relationships and evaluate psychiatric status on-line as opposed to in the lab.